Search Results - "Blair, Eric"

The Cajal body protein p80-coilin forms a complex with the adenovirus L4-22K protein and facilitates the nuclear export of adenovirus mRNA by White, Laura, Erbay, Bilgi, Blair, G Eric

“…The architecture of sub-nuclear structures of eucaryotic cells is often changed during the infectious cycle of many animal and plant viruses. Cajal bodies…”
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Viruses and Cajal Bodies: A Critical Cellular Target in Virus Infection? by Lettin, Lucy, Erbay, Bilgi, Blair, G Eric

“…Nuclear bodies (NBs) are dynamic structures present in eukaryotic cell nuclei. They are not bounded by membranes and are often considered biomolecular…”
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Merkel Cell Polyomavirus Small T Antigen Targets the NEMO Adaptor Protein To Disrupt Inflammatory Signaling by Griffiths, David A, Abdul-Sada, Hussein, Knight, Laura M, Jackson, Brian R, Richards, Kathryn, Prescott, Emma L, Peach, A Howard S, Blair, G Eric, Macdonald, Andrew, Whitehouse, Adrian

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MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer by Morgan, Ethan L, Patterson, Molly R, Ryder, Emma L, Lee, Siu Yi, Wasson, Christopher W, Harper, Katherine L, Li, Yigen, Griffin, Stephen, Blair, G Eric, Whitehouse, Adrian, Macdonald, Andrew

“…Human papillomaviruses (HPV) are a major cause of malignancy worldwide. They are the aetiological agents of almost all cervical cancers as well as a sub-set of…”
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High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors by WETHERILL, Laura F, HOLMES, Kristopher K, GRIFFIN, Stephen, MACDONALD, Andrew, VEROW, Mark, MÜLLER, Marietta, HOWELL, Gareth, HARRIS, Mark, FISHWICK, Colin, STONEHOUSE, Nicola, FOSTER, Richard, BLAIR, G. Eric

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Impact of Human Adenovirus Type 3 Dodecahedron on Host Cells and Its Potential Role in Viral Infection by FENDER, Pascal, HALL, Kathryn, SCHOEHN, Guy, BLAIR, G. Eric

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The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes by Richards, Kathryn H., Wasson, Christopher W., Watherston, Oliver, Doble, Rosella, Eric Blair, G., Wittmann, Miriam, Macdonald, Andrew

“…High-risk human papillomaviruses (HPV) are the etiological pathogen of cervical and a number of ano-genital cancers. How HPVs overcome the significant barriers…”
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Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness by Nwogu, Nnenna, Boyne, James R, Dobson, Samuel J, Poterlowicz, Krzysztof, Blair, G Eric, Macdonald, Andrew, Mankouri, Jamel, Whitehouse, Adrian

“…Merkel cell carcinoma (MCC) is an aggressive skin cancer with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) is recognised…”
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Human papillomavirus E7 oncoprotein increases production of the anti-inflammatory interleukin-18 binding protein in keratinocytes by Richards, Kathryn H, Doble, Rosella, Wasson, Christopher W, Haider, Mohammed, Blair, G Eric, Wittmann, Miriam, Macdonald, Andrew

“…Human papillomavirus (HPV) can successfully evade the host immune response to establish a persistent infection. We show here that expression of the E7…”
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Unity and diversity in the human adenoviruses: exploiting alternative entry pathways for gene therapy by Hall, Kathryn, Blair Zajdel, Maria E, Blair, G Eric

“…Human Ads (adenoviruses) have been extensively utilized for the development of vectors for gene transfer, as they infect many cell types and do not integrate…”
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Novel impedimetric immunosensor for the detection and quantitation of Adenovirus using reduced antibody fragments immobilized onto a conducting copolymer surface by Caygill, Rebecca L., Hodges, Christopher S., Holmes, Joanne L., Higson, Séamus P.J., Blair, G. Eric, Millner, Paul A.

“…► Whole Adenovirus and fiber proteins were produced; fibers were used to make IgG. ► IgG were reduced to half-antibody fragments, purified using HPLC and…”
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An RNA aptamer provides a novel approach for the induction of apoptosis by targeting the HPV16 E7 oncoprotein by Nicol, Clare, Cesur, Özlem, Forrest, Sophie, Belyaeva, Tamara A, Bunka, David H J, Blair, G Eric, Stonehouse, Nicola J

“…Human papillomavirus 16 (HPV16) is a high-risk DNA tumour virus, which is a major causative agent of cervical cancer. Cellular transformation is associated…”
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Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells by Meyers, Jennifer Hartt, Justement, J Shawn, Hallahan, Claire W, Blair, Eric T, Sun, Yongming A, O'Shea, M Angeline, Roby, Gregg, Kottilil, Shyam, Moir, Susan, Kovacs, Colin M, Chun, Tae-Wook, Fauci, Anthony S

“…Plasmacytoid dendritic cells (pDCs) are important mediators of innate immunity that act mainly through secretion of interferon (IFN)-alpha. Previous studies…”
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CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells by Orchard-Webb, David J, Lee, Thong Chuan, Cook, Graham P, Blair, G Eric

“…Deregulated expression of the transmembrane glycoprotein CDCP1 (CUB domain-containing protein-1) has been detected in several cancers including colon, lung,…”
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Gene Profiling in the Livers of Wild-type and PPARα-Null Mice Exposed to Perfluorooctanoic Acid by Rosen, Mitchell B., Abbott, Barbara D., Wolf, Douglas C., Corton, J. Christopher, Wood, Carmen R., Schmid, Judith E., Das, Kaberi P., Zehr, Robert D., Blair, Eric T., Lau, Christopher

“…Health concerns have been raised because perfluorooctanoic acid (PFOA) is commonly found in the environment and can be detected in humans. In rodents, PFOA is…”
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The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Enhances E1A Functional Activity by Dallaire, Frédéric, Schreiner, Sabrina, Blair, G Eric, Dobner, Thomas, Branton, Philip E, Blanchette, Paola

“…Human adenovirus (Ad) E1A proteins have long been known as the central regulators of virus infection as well as the major source of adenovirus oncogenic…”
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The role of Cajal bodies in the expression of late phase adenovirus proteins by James, Nicola J, Howell, Gareth J, Walker, John H, Blair, G. Eric

“…Abstract Cajal bodies (CBs) are subnuclear structures involved in RNA metabolism. Here we show that, following infection of HeLa cells by adenovirus type 5…”
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Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins by GEORGOPOULOS, Nikolaos T, PROFFITT, Joanne L, BLAIR, G. Eric

“…We have examined the possibility that the E7 proteins of the high-risk human papillomavirus (HPV) type 16 and 18 and the oncogenic adenovirus (Ad) type 12 E1A…”
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The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F by Dallaire, Frédéric, Schreiner, Sabrina, Blair, G Eric, Dobner, Thomas, Branton, Philip E, Blanchette, Paola

“…The human adenovirus E4orf6/E1B55K E3 ubiquitin ligase is well known to promote viral replication by degrading an increasing number of cellular proteins that…”
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Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing by Scott, Gina B, Bowles, Paul A, Wilson, Erica B, Meade, Josephine L, Low, Boon Chuan, Davison, Adam, Blair, G Eric, Cook, Graham P

“…Cytotoxic lymphocytes eliminate infected cells and tumours via the perforin-mediated delivery of pro-apoptotic serine proteases known as granzymes. Granzyme B…”
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