Acute pericarditis and severe acute respiratory syndrome coronavirus 2: Case report

•Pericarditis may be adominant manifestation of severe acute respiratory syndrome coronavirus 2 infection.•Pericarditis should be considered in the patient with chest pain, a normal coronary angiogram, and ST elevation on electrocardiogram.•Basic clinical tools in the setting of the coronavirus dise...

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Bibliographic Details
Published in:	International journal of infectious diseases Vol. 101; pp. 180 - 182
Main Authors:	Blagojevic, Nikola R., Bosnjakovic, Dragana, Vukomanovic, Vladan, Arsenovic, Srdjan, Lazic, Jelena Suzic, Tadic, Marijana
Format:	Journal Article
Language:	English
Published:	Canada Elsevier Ltd 01-12-2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases Elsevier
Subjects:	Case Report COVID-19 COVID-19 - complications COVID-19 - diagnosis COVID-19 - diagnostic imaging COVID-19 - virology Echocardiography Electrocardiography Hospitalization Humans Lung - diagnostic imaging Male Middle Aged Pericarditis Pericarditis - complications Pericarditis - diagnosis Pericarditis - diagnostic imaging Pericarditis - virology Pneumonia, Viral - diagnosis SARS-CoV-2 SARS-CoV-2 - genetics SARS-CoV-2 - isolation & purification SARS-CoV-2 - physiology Tomography, X-Ray Computed COVID-19 Pericarditis SARS-CoV-2
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Summary:	•Pericarditis may be adominant manifestation of severe acute respiratory syndrome coronavirus 2 infection.•Pericarditis should be considered in the patient with chest pain, a normal coronary angiogram, and ST elevation on electrocardiogram.•Basic clinical tools in the setting of the coronavirus disease 2019 epidemic should not be forgotten and may be of great help. We present the case of a 51-year-old patient with acute pericarditis as the dominant manifestation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patient was admitted to the emergency department during a coronavirus disease 2019 (COVID-19) outbreak with a suspected ST-elevation myocardial infarction. A coronary angiogram was normal. Real-time reverse transcriptase PCR for the detection of nucleic acid from SARS-CoV-2 in a nasopharyngeal swab was positive. Laboratory tests revealed an increased white blood cell count, with neutrophilia and lymphocytopenia, elevated level of C-reactive protein, borderline elevated erythrocyte sedimentation rate, and slightly elevated interleukin 6. Echocardiography showed a hyperechogenic pericardium posterolaterally with minimal localized pericardial effusion. A chest computed tomography scan showed a small zone of ground-glass opacity in the right lower lobe (classified as CO-RADS 3). In patients with chest pain, ST elevation on electrocardiogram, a normal coronary angiogram, and suspected COVID-19, we should think of pericarditis as an unusual presentation of SARS-CoV-2 infection.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Report-1
ISSN:	1201-9712 1878-3511 1878-3511
DOI:	10.1016/j.ijid.2020.09.1440