Search Results - "Blagodatskikh, Konstantin"

Fragmentation Through Polymerization (FTP): A new method to fragment DNA for next-generation sequencing by Ignatov, Konstantin B, Blagodatskikh, Konstantin A, Shcherbo, Dmitry S, Kramarova, Tatiana V, Monakhova, Yulia A, Kramarov, Vladimir M

“…Fragmentation of DNA is the very important first step in preparing nucleic acids for next-generation sequencing. Here we report a novel Fragmentation Through…”
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Improved DOP-PCR (iDOP-PCR): A robust and simple WGA method for efficient amplification of low copy number genomic DNA by Blagodatskikh, Konstantin A, Kramarov, Vladimir M, Barsova, Ekaterina V, Garkovenko, Alexey V, Shcherbo, Dmitriy S, Shelenkov, Andrew A, Ustinova, Vera V, Tokarenko, Maria R, Baker, Simon C, Kramarova, Tatiana V, Ignatov, Konstantin B

“…Whole-genome amplification (WGA) techniques are used for non-specific amplification of low-copy number DNA, and especially for single-cell genome and…”
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COVID-19 pandemic in Saint Petersburg, Russia: Combining population-based serological study and surveillance data by Barchuk, Anton, Skougarevskiy, Dmitriy, Kouprianov, Alexei, Shirokov, Daniil, Dudkina, Olga, Tursun-Zade, Rustam, Sergeeva, Mariia, Tychkova, Varvara, Komissarov, Andrey, Zheltukhina, Alena, Lioznov, Dmitry, Isaev, Artur, Pomerantseva, Ekaterina, Zhikrivetskaya, Svetlana, Sofronova, Yana, Blagodatskikh, Konstantin, Titaev, Kirill, Barabanova, Lubov, Danilenko, Daria

“…The COVID-19 pandemic in Russia has already resulted in 500,000 excess deaths, with more than 5.6 million cases registered officially by July 2021…”
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Genetic screening of an endemic mutation in the DYSF gene in an isolated, mountainous population in the Republic of Dagestan by Bardakov, Sergey N, Deev, Roman V, Isaev, Аrtur А, Khromov-Borisov, Nikita N, Kopylov, Evgeniy D, Savchuk, Мaria R, Pushkin, Maxim S, Presnyakov, Evgeniy V, Magomedova, Raisat M, Achmedova, Patimat G, Umakhanova, Zoya R, Kaimonov, Vladimir S, Musatova, Elizaveta V, Blagodatskikh, Konstantin А, Tveleneva, Aleksandra А, Sofronova, Yana V, Yakovlev, Ivan A

“…Dysferlinopathy has a high prevalence in relatively isolated ethnic groups where consanguineous marriages are characteristic and/or the founder effect exists…”
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A strong strand displacement activity of thermostable DNA polymerase markedly improves the results of DNA amplification by Ignatov, Konstantin B, Barsova, Ekaterina V, Fradkov, Arkady F, Blagodatskikh, Konstantin A, Kramarova, Tatiana V, Kramarov, Vladimir M

“…The sensitivity and robustness of various DNA detection and amplification techniques are to a large extent determined by the properties of the DNA polymerase…”
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The Detection of Cancer Epigenetic Traces in Cell-Free DNA by Koval, Anastasia P, Blagodatskikh, Konstantin A, Kushlinskii, Nikolay E, Shcherbo, Dmitry S

“…Nucleic acid fragments found in blood circulation originate mostly from dying cells and carry signs pointing to specific features of the parental cell types…”
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Combinations of PCR and Isothermal Amplification Techniques Are Suitable for Fast and Sensitive Detection of SARS-CoV-2 Viral RNA by Varlamov, Dmitriy A., Blagodatskikh, Konstantin A., Smirnova, Evgenia V., Kramarov, Vladimir M., Ignatov, Konstantin B.

“…The newly identified coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes coronavirus disease 2019 (COVID-19) and has affected…”
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AScall - Automatic Allele-Specific qPCR Analysis by Blagodatskikh, Konstantin, Romaniuk, Dmitrii, Malko, Dmitry

“…Minor histocompatibility antigens (MiHA) are critical elements for the immune response after allogeneic hematopoietic stem cell transplantation. They may cause…”
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Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial by Kudriavtsev, Aleksandr V, Vakhrusheva, Anna V, Kryuchkov, Nickolay A, Frolova, Maria E, Blagodatskikh, Konstantin A, Ivanishin, Taras V, Djonovic, Milana, Romanovskaya-Romanko, Ekaterina A, Kovalenko, Anton N, Lioznov, Dmitry A, Zubkova, Tatiana G, Teplykh, Svetlana V, Oseshnyuk, Rodion A, Stukova, Marina A, Isaev, Artur A, Krasilnikov, Igor V

“…COVID-19, being a life-threatening infection that evolves rapidly, remains a major public health concern calling for the development of vaccines with broad…”
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Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer by Koval, Anastasia P, Khromova, Alexandra S, Blagodatskikh, Konstantin A, Zhitnyuk, Yulia V, Shtykova, Yanina A, Alferov, Aleksandr A, Kushlinskii, Nikolay E, Shcherbo, Dmitry S

“…Cell-free DNA (cfDNA) testing is the core of most liquid biopsy assays. In particular, cfDNA fragmentation features could facilitate non-invasive cancer…”
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SARS-CoV-2 Subunit Virus-like Vaccine Demonstrates High Safety Profile and Protective Efficacy: Preclinical Study by Vakhrusheva, Anna V, Kudriavtsev, Aleksandr V, Kryuchkov, Nickolay A, Deev, Roman V, Frolova, Maria E, Blagodatskikh, Konstantin A, Djonovic, Milana, Nedorubov, Andrey A, Odintsova, Elena, Ivanov, Aleksandr V, Romanovskaya-Romanko, Ekaterina A, Stukova, Marina A, Isaev, Artur A, Krasilnikov, Igor V

“…Public health threat coming from a rapidly developing COVID-19 pandemic calls for developing safe and effective vaccines with innovative designs. This paper…”
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Algorithms for automated detection of hook effect-bearing amplification curves by Burdukiewicz, Michał, Spiess, Andrej-Nikolai, Blagodatskikh, Konstantin A., Lehmann, Werner, Schierack, Peter, Rödiger, Stefan

“…Amplification curves from quantitative Real-Time PCR experiments typically exhibit a sigmoidal shape. They can roughly be divided into a ground or baseline…”
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High DNA melting activity of extremophyte Eutrema salsugineum cold shock domain proteins EsCSDP1 and EsCSDP3 by Zlobin, Nikolai, Evlakov, Konstantin, Alekseev, Yakov, Blagodatskikh, Konstantin, Babakov, Aleksei, Taranov, Vasiliy

“…Plant cold shock domain proteins (CSDP) participate in maintenance of plant stress tolerance and in regulating their development. In the present paper we show…”
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Enabling reproducible real-time quantitative PCR research: the RDML package by Rödiger, Stefan, Burdukiewicz, Michal, Spiess, Andrej-Nikolai, Blagodatskikh, Konstantin

“…Reproducibility, a cornerstone of research, requires defined data formats, which include the setup and output of experiments. The real-time PCR data markup…”
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Fragmentation Through Polymerization by Ignatov, Konstantin B, Blagodatskikh, Konstantin A, Shcherbo, Dmitry S, Kramarova, Tatiana V, Monakhova, Yulia A, Kramarov, Vladimir M

“…Fragmentation of DNA is the very important first step in preparing nucleic acids for next-generation sequencing. Here we report a novel Fragmentation Through…”
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PCRedux: A Quantitative PCR Machine Learning Toolkit by Burdukiewicz, Michał, Spiess, Andrej-Nikolai, Rafacz, Dominik, Blagodatskikh, Konstantin, Rödiger, Stefan

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Improved DOP-PCR by Blagodatskikh, Konstantin A, Kramarov, Vladimir M, Barsova, Ekaterina V, Garkovenko, Alexey V, Shcherbo, Dmitriy S, Shelenkov, Andrew A, Ustinova, Vera V, Tokarenko, Maria R, Baker, Simon C, Kramarova, Tatiana V, Ignatov, Konstantin B

“…Whole-genome amplification (WGA) techniques are used for non-specific amplification of low-copy number DNA, and especially for single-cell genome and…”
Get full text

COVID-19 pandemic in Saint Petersburg, Russia: Combining population-based serological study and surveillance data by Anton Barchuk, Dmitriy Skougarevskiy, Alexei Kouprianov, Daniil Shirokov, Olga Dudkina, Rustam Tursun-zade, Mariia Sergeeva, Varvara Tychkova, Andrey Komissarov, Alena Zheltukhina, Dmitry Lioznov, Artur Isaev, Ekaterina Pomerantseva, Svetlana Zhikrivetskaya, Yana Sofronova, Konstantin Blagodatskikh, Kirill Titaev, Lubov Barabanova, Daria Danilenko

“…Background The COVID-19 pandemic in Russia has already resulted in 500,000 excess deaths, with more than 5.6 million cases registered officially by July 2021…”
Get full text