Search Results - "Blackwell, G J"

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation by Flower, R J, Blackwell, G J

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GLUCOCORTICOIDS INDUCE THE FORMATION AND RELEASE OF ANTI‐INFLAMMATORY AND ANTI‐PHOSPHOLIPASE PROTEINS INTO THE PERITONEAL CAVITY OF THE RAT by BLACKWELL, G.J., CARNUCCIO, ROSA, ROSA, M., FLOWER, R.J., LANGHAM, C.S.J., PARENTE, L., PERSICO, PAOLA, RUSSELL‐SMITH, N.C., STONE, D.

“…1 Dexamethasone and hydrocortisone induce the release of anti‐phospholipase proteins into the peritoneal cavities of rats. 2 Adrenocorticotropic hormone (ACTH)…”
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Reduction by prostacyclin of acetaminophen-induced liver toxicity in the mouse by Guarner, F, Boughton-Smith, N K, Blackwell, G J, Moncada, S

“…The effect of prostacyclin on acetaminophen-induced liver injury has been investigated in the mouse. Two structurally unrelated thromboxane synthetase…”
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Specificity and inhibition of glucocorticoid‐induced macrocortin secretion from rat peritoneal macrophages by Blackwell, Geoffrey J.

“…1 The secretion of the phospholipase A2‐inhibitor macrocortin and the binding of dexamethasone were studied in suspensions of rat peritoneal macrophages. 2…”
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Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism by Armstrong, J. M, Blackwell, G. J, Flower, R. J, McGiff, J. C, Mullane, K. M, Vane, J. R

“…Noradrenaline releases prostaglandins in the kidney, and in rats these augment rather than reduce vasoconstriction produced by the amine. Homogenates of…”
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Stimulation and inhibition of secretion by phorbol myristate acetate in different cell types by Blackwell, G J, Bonser, R W, Dawson, J, Garland, L G

“…In washed human platelets and in HL60 granulocytes phorbol myristate acetate (PMA, 1-2000nM) synergised with threshold concentrations of secretogogues to…”
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Synthesis and PAF antagonist activity of some 2,5-diaryltetrahydrofurans incorporating PAF-like functional groups by Smith, S, Blackwell, G.J., Demaine, D.A., Garland, L.G., Hodson, H.F., Hyde, R.M., Parke, A.J., Rose, V.S., Sawyer, D.A., Tilling, L

“…This paper describes the synthesis and structure-activity relationships of a series of 2,5-diaryltetrahydrofurans, as specific and potent antagonists at the…”
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Anti-inflammatory steroids induce biosynthesis of a phospholipase A 2 inhibitor which prevents prostaglandin generation by FLOWER, R. J, BLACKWELL, G. J

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1-phenyl-3-pyrazolidone: an inhibitor of cyclo-oxygenase and lipoxygenase pathways in lung and platelets by Blackwell, G J, Flower, R J

“…1-phenyl-3-pyrazolidone (phenidone) is a commercially available reagent used in the photographic industry. When tested as an inhibitor of arachidonic acid…”
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Peptides incorporating electrophilic glutamine analogues as potential transglutaminase inhibitors by Doyle, P M, Harris, C J, Carter, K R, Simpkin, D S, Bailey-Smith, P, Stone, D, Russell, L, Blackwell, G J

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RAPID REDUCTION OF PROSTAGLANDIN 15‐HYDROXY DEHYDROGENASE ACTIVITY IN RAT TISSUES AFTER TREATMENT WITH PROTEIN SYNTHESIS INHIBITORS by BLACKWELL, G.J., FLOWER, R.J., VANE, J.R.

“…1 The capacity of rat kidneys to metabolize prostaglandins is rapidly lost when de novo protein synthesis is reduced by cycloheximide and puromycin. Enzyme…”
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Metabolic and cellular profile of wether goats: protein fractions and lactate dehydrogenase isoenzymes- reference values by Blackwell, J G, Libby, D W

“…Blood serum concentrations of electrolytes; mineral, serum protein, and biochemical components; serum lactate dehydrogenase (LDH) activity; and blood cellular…”
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Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids by Blackwell, Geoffrey J, Carnuccio, Rosa, Rosa, Massimo Di, Flower, Roderick J, Parente, Luca, Persico, Paola

“…Anti-inflammatory glucocorticoids inhibit prostaglandin (PG) biosynthesis by preventing arachidonic acid release from phospholipids rather than inhibiting the…”
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Chronic lead poisoning (chronic plumbism) in a ewe by Blackwell, J G

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Lightning incriminated in the sudden death of 18 steers by Blackwell, J G

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Some characteristics of the prostaglandin synthesizing system in rabbit kidney microsomes by Blackwell, G J, Flower, R J, Vane, J R

“…The prostaglandin synthesizing system in rabbit kidney microsomes was characterised using a radiometric assay. Three prostaglandins (F2alpha, E2 and D2) were…”
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ON THE PREPARATION OF HIGHLY PURIFIED SLOW REACTING SUBSTANCE OF ANAPHYLAXIS (SRS‐A) FROM BIOLOGICAL EXTRACTS by BLACKWELL, G.J., BURKA, J.F., FLOWER, R.J., TORKINGTON, P.

“…1 Very highly purified (> 100,000 u/mg) slow reacting substance of anaphylaxis (SRS‐A) has been prepared by reversed phase high pressure liquid chromatographic…”
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Suppression of arachidonate oxidation by glucocorticoid-induced antiphospholipase peptides by Blackwell, G J, Carnuccio, R, Di Rosa, M, Flower, R J, Ivanyi, J, Langham, C S, Parente, L, Persico, P, Wood, J

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A RAPID METHOD FOR THE ESTIMATION OF PROSTAGLANDIN 15‐HYDROXYDEHYDROGENASE ACTIVITY AND ITS APPLICATION TO PHARMACOLOGY by BLACKWELL, G.J., FLOWER, R.J.

“…1 A novel double‐isotope assay for prostaglandin 15‐hydroxydehydrogenase (PGDH) is described. 2 The assay is simple, rapid, precise, completely specific for…”
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Inhibition of phospholipase by Blackwell, G J, Flower, R J

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