Search Results - "Black, R.M."

Biomonitoring of Exposure to Chemical Warfare Agents: A Review by Noort, D., Benschop, H.P., Black, R.M.

“…In this report an overview of the methods currently available for detection of exposure to a number of chemical warfare agents (CWA), i.e., sulfur mustard,…”
Get full text

The Inflammation-Based Index Can Predict Response and Improve Patient Selection in NETs Treated With PRRT: A Pilot Study by Black, James R M, Atkinson, Stephen R, Singh, Amal, Evans, Joanne, Sharma, Rohini

“…Abstract Background Peptide receptor radionuclide therapy (PRRT) is an effective treatment of certain patients with metastatic neuroendocrine tumors (NETs)…”
Get full text

Nanopatterned Titanium Implants Accelerate Bone Formation In Vivo by Greer, Andrew I.M, Goriainov, Vitali, Kanczler, Janos, Black, Cameron R.M, Turner, Lesley-Anne, Meek, Robert M.D, Burgess, Karl, MacLaren, Ian, Dalby, Matthew J, Oreffo, Richard O.C, Gadegaard, Nikolaj

“…Accelerated de novo formation of bone is a highly desirable aim of implants targeting musculoskeletal injuries. To date, this has primarily been addressed by…”
Get full text

DEXAMETHASONE HAS MINIMAL EFFECT ON INTRATISSUE PROTEOME IN HUMAN OSTEOCHONDRAL PTOA MODEL by Black, R.M., Lindblom, K., Chubinskaya, S., Grodzinsky, A.J., Önnerfjord, P.

Get full text

Effects of disease and dexamethasone on human cartilage breakdown kinetics by Black, R.M., Wang, Y., Lorenzo, P., Chubinskaya, S., Grodzinsky, A.J., Önnerfjord, P.

Get full text

Genetic and non-genetic clonal diversity in cancer evolution by Black, James R. M., McGranahan, Nicholas

“…The observation and analysis of intra-tumour heterogeneity (ITH), particularly in genomic studies, has advanced our understanding of the evolutionary forces…”
Get full text

COVID-19: the case for health-care worker screening to prevent hospital transmission by Black, James R M, Bailey, Chris, Przewrocka, Joanna, Dijkstra, Krijn K, Swanton, Charles

Get full text

Age-related macular degeneration: genome-wide association studies to translation by Black, James R.M., Clark, Simon J.

“…In recent years, genome-wide association studies (GWAS), which are able to analyze the contribution to disease of genetic variations that are common within a…”
Get full text

Tracking Cancer Evolution through the Disease Course by Bailey, Chris, Black, James R M, Reading, James L, Litchfield, Kevin, Turajlic, Samra, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Swanton, Charles

“…During cancer evolution, constituent tumor cells compete under dynamic selection pressures. Phenotypic variation can be observed as intratumor heterogeneity,…”
Get more information

Cancer Research: The Lessons to Learn from COVID-19 by Bailey, Chris, Black, James R M, Swanton, Charles

“…The COVID-19 pandemic has caused widespread disruption of cancer clinical trials due to the restrictions on nonessential services and the reallocation of…”
Get more information

Case 12-1995: A 59-year-old diabetic man with acute renal failure and a pulmonary infiltrate by Black, R.M, Meehan, S.M

“…Presentation of Case A 59-year-old man was admitted to the hospital because of possible pneumonia and acute renal failure. He had a 17-year history of…”
Get full text

Decoding the interplay between genetic and non-genetic drivers of metastasis by Karras, Panagiotis, Black, James R. M., McGranahan, Nicholas, Marine, Jean-Christophe

“…Metastasis is a multistep process by which cancer cells break away from their original location and spread to distant organs, and is responsible for the vast…”
Get full text

Clinical implications of heterogeneity in PD-L1 immunohistochemical detection in hepatocellular carcinoma: the Blueprint-HCC study by Pinato, David J., Mauri, Francesco A., Spina, Paolo, Cain, Owen, Siddique, Abdul, Goldin, Robert, Victor, Stephane, Pizio, Corinna, Akarca, Ayse U., Boldorini, Renzo L., Mazzucchelli, Luca, Black, James R. M., Shetty, Shishir, Marafioti, Teresa, Sharma, Rohini

“…Programmed cell death ligand-1 immunohistochemical detection (PD-L1 IHC) is a putative predictor of response to PD-1/PD-L1-targeted checkpoint inhibitors…”
Get full text

Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply by Black, James R M, Bailey, Chris, Przewrocka, Joanna, Dijkstra, Krijn K, Gandhi, Sonia, Gamblin, Steve, Barrell, Sam, Swanton, Charles

Get full text

Bone induction at physiological doses of BMP through localization by clay nanoparticle gels by Gibbs, D.M.R, Black, C.R.M, Hulsart-Billstrom, G, Shi, P, Scarpa, E, Oreffo, R.O.C, Dawson, J.I

“…Abstract Bone Morphogenic Protein 2 (BMP2) can induce ectopic bone. This ability, which first motivated the widespread application of BMP2 in fracture healing…”
Get full text

Abstract S12-02: Comprehensive meta-analysis of COVID-19 mortality rates for 22 cancer subtypes from the Reboot: COVID-Cancer Project, an interactive resource with aggregated data from 21,839 cancer patients by Duffy, Emily-Claire, Fan, Kelly, Advani, Shailesh, Bailey, Chris, Black, James R.M., Strauss, Ellie, Crittenden, Devon, Bhangdia, Thomas, Imbacuan, Allyson, Yang, Emily, Britt, Allison, Mangalath, Pradeep, Swanton, Charles, Kleiman, Laura B., Del Vecchio Fitz, Catherine

“…Abstract Introduction: The COVID-19 pandemic continues to disproportionately impact people with cancer. Mortality estimates among cancer patients vary and are…”
Get full text

COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA.1, BA.2, BA.4/5 or Delta associates with similar illness duration, symptom severity and viral kinetics, irrespective of vaccination history by Townsley, Hermaleigh, Gahir, Joshua, Russell, Timothy W, Greenwood, David, Carr, Edward J, Dyke, Matala, Adams, Lorin, Miah, Murad, Clayton, Bobbi, Smith, Callie, Miranda, Mauro, Mears, Harriet V, Bailey, Chris, Black, James R M, Fowler, Ashley S, Crawford, Margaret, Wilkinson, Katalin, Hutchinson, Matthew, Harvey, Ruth, O'Reilly, Nicola, Kelly, Gavin, Goldstone, Robert, Beale, Rupert, Papineni, Padmasayee, Corrah, Tumena, Gilson, Richard, Caidan, Simon, Nicod, Jerome, Gamblin, Steve, Kassiotis, George, Libri, Vincenzo, Williams, Bryan, Gandhi, Sonia, Kucharski, Adam J, Swanton, Charles, Bauer, David L V, Wall, Emma C

“…SARS-CoV-2 variant Omicron rapidly evolved over 2022, causing three waves of infection due to sub-variants BA.1, BA.2 and BA.4/5. We sought to characterise…”
Get full text

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London by Bailey, Chris, Sanderson, Theo, Townsley, Hermaleigh, Goldman, Jacki, Black, James R M, Young, George, Goldstone, Robert, Fowler, Ashley S, Ward, Sophia, Jackson, Deborah J, Cubitt, Laura, Dearing, Vicky, O'Neil, Olga, Crawford, Marg, Snell, Daniel, Finadis, Makis, Edwards, Amelia, Perez-Lloret, Jimena, Gahir, Joshua, Carr, Edward J, Riddell, Andy, Aitken, Jim, Ambrose, Karen, Sawyer, Chelsea, O'Reilly, Nicola, Caidan, Simon, Wu, Mary Y, Walker, Philip A, Hindmarsh, Steve, Howell, Michael, Jordan, Andrew, Fleming, James, Houlihan, Catherine, Nastouli, Eleni, Moores, Rachel, Hsu, Desmond, Papineni, Padmasayee, Corrah, Tumena, Gilson, Richard, MacRae, James, Hubank, Michael, Van As, Nicholas, Turajlic, Samra, Beale, Rupert, Levi, Marcel, Barrell, Sam, Williams, Bryan, Gamblin, Steve, Nicod, Jerome, Gandhi, Sonia, Bauer, David L V, Wall, Emma C, Swanton, Charles

Get full text

Gene of the month: Axl by Brown, Matthew, Black, James R M, Sharma, Rohini, Stebbing, Justin, Pinato, David J

“…The interaction between Axl receptor tyrosine kinase and its main ligand Gas6 has been implicated in the progression of a wide number of malignancies. More…”
Get more information

Intra-tumoral heterogeneity in the expression of programmed-death (PD) ligands in isogeneic primary and metastatic lung cancer: Implications for immunotherapy by Pinato, David J., Shiner, Robert J., White, Solomon D. T., Black, James R. M., Trivedi, Pritesh, Stebbing, Justin, Sharma, Rohini, Mauri, Francesco A.

“…Purpose: There is inconclusive evidence to suggest the expression of programmed cell death (PD) ligand 1 (PD-L1) is a putative predictor of response to…”
Get full text