Search Results - "Black, Gillian"
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Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients
Published in PloS one (23-07-2012)“…Although tuberculosis (TB) causes more deaths than any other pathogen, most infected individuals harbor the pathogen without signs of disease. We explored the…”
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Metabolite changes in blood predict the onset of tuberculosis
Published in Nature communications (06-12-2018)“…New biomarkers of tuberculosis (TB) risk and disease are critical for the urgently needed control of the ongoing TB pandemic. In a prospective multisite study…”
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Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: preliminary report
Published in BMC pulmonary medicine (16-05-2009)“…Interferon gamma release assays, including the QuantiFERON TB Gold In Tube (QFT) have been shown to be accurate in diagnosing Mycobacterium tuberculosis…”
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T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection
Published in Nature medicine (01-01-2023)“…Antigen-specific, MHC-restricted αβ T cells are necessary for protective immunity against Mycobacterium tuberculosis , but the ability to broadly study these…”
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Steps Toward Engagement Integrity: Learning From Participatory Visual Methods in Marginalized South African Communities
Published in Frontiers in public health (27-06-2022)“…Community engagement and involvement have been increasingly recognized as an ethical and valuable component of health science research over the past two…”
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Using hand maps to understand how intersecting inequalities affect possibilities for community safety in Cape Town
Published in Community development journal (01-01-2020)“…Abstract Knowledge about what builds and what blocks pathways to accountability in South African townships could be strengthened by better understanding the…”
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Confluency: Development of an Interactive Mobile Art Exhibit and Resource on Water Justice in South Africa and Canada
Published in Health promotion practice (19-11-2024)“…Water justice—equitable, reliable access to clean, sufficient water, and the knowledge and mechanisms related to its management—is a key global social justice…”
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Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area
Published in PloS one (05-06-2012)“…Recent interferon gamma (IFN-γ)-based studies have identified novel Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens as diagnostic…”
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Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis
Published in The Journal of experimental medicine (23-11-2009)“…Approximately 20% of persons living in areas hyperendemic for tuberculosis (TB) display persistent lack of tuberculin skin test (TST) reactivity and appear to…”
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Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa
Published in PloS one (10-09-2013)“…Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to…”
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Reflections on the ethics of participatory visual methods to engage communities in global health research
Published in Problemi di bioetica (01-01-2018)“…There is a growing body of literature describing conceptual frameworks for working with participatory visual methods (PVM). Through a global health lens, this…”
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Identification of a Major Locus, TNF1, That Controls BCG-Triggered Tumor Necrosis Factor Production by Leukocytes in an Area Hyperendemic for Tuberculosis
Published in Clinical infectious diseases (01-10-2013)“…Background. Tumor necrosis factor (TNF) is a key immune regulator of tuberculosis resistance, as exemplified by the highly increased risk of tuberculosis…”
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Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
Published in BMC infectious diseases (20-01-2012)“…Confirming tuberculosis (TB) disease in suspects in resource limited settings is challenging and calls for the development of more suitable diagnostic tools…”
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Serologic diagnosis of tuberculosis by combining Ig classes against selected mycobacterial targets
Published in The Journal of infection (01-12-2014)“…Summary Introduction Accurate, simple and cost-effective diagnostic tests are needed for diagnosis of active tuberculosis (TB). Serodiagnosis is attractive as…”
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Medroxyprogesterone acetate alters Mycobacterium bovis BCG-induced cytokine production in peripheral blood mononuclear cells of contraceptive users
Published in PloS one (08-09-2011)“…Most individuals latently infected with Mycobacterium tuberculosis (M.tb) contain the infection by a balance of effector and regulatory immune responses. This…”
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An evaluation of commercial fluorescent bead-based luminex cytokine assays
Published in PloS one (02-07-2008)“…The recent introduction of fluorescent bead-based technology, allowing the measurement of multiples analytes in a single 25-50 microl sample has revolutionized…”
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High Heritability of Antimycobacterial Immunity in an Area of Hyperendemicity for Tuberculosis Disease
Published in The Journal of infectious diseases (01-01-2010)“…Human antimycobacterial immunity is a critical component of tuberculosis (TB) pathogenesis that is often used to infer the presence of TB infection. We report…”
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BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: A preliminary investigation in a South African population
Published in Progress in neuro-psychopharmacology & biological psychiatry (10-01-2013)“…We evaluated the role that selected variants in serotonin transporter (5-HTT), dopamine receptor 2 (DRD2) and brain-derived neurotrophic factor (BDNF) genes…”
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Immunogenicity of Novel DosR Regulon-Encoded Candidate Antigens of Mycobacterium tuberculosis in Three High-Burden Populations in Africa
Published in Clinical and Vaccine Immunology (01-08-2009)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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