Search Results - "Bkhaitan, Majdi M."
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Proapoptotic Activity of Achillea membranacea Essential Oil and Its Major Constituent 1,8-Cineole against A2780 Ovarian Cancer Cells
Published in Molecules (Basel, Switzerland) (30-03-2020)“…Among the hundreds of reported species, (Labill.) DC. is one of the six that grow in Jordan. Many species of this genus are used in folk medicine to treat a…”
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2
Synthesis and in Vivo Lipid-Lowering Activity of Novel Imidazoles-5-carboxamide Derivatives in Triton-WR-1339-Induced Hyperlipidemic Wistar Rats
Published in Chemical & pharmaceutical bulletin (01-10-2018)“…A new series of imidazole-5-carboxamide derivatives were prepared and tested for their anti-hyperlipidemic activity in Triton-WR-1339-induced hyperlipidemic…”
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3
Molecular dynamics simulations reveal structural insights into inhibitor binding modes and mechanism of casein kinase II inhibitors
Published in Journal of biomolecular structure & dynamics (24-03-2019)“…Casein kinase-II, a member of protein kinase family, plays significant role in different cellular processes such as cell growth, differentiation,…”
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4
Identification of potent virtual leads and ADME prediction of isoxazolidine podophyllotoxin derivatives as topoisomerase II and tubulin inhibitors
Published in Journal of molecular graphics & modelling (01-05-2017)“…[Display omitted] •Different isoxazolidine podophyllotoxin analogues were designed and docked into tubulin and topoisomerase proteins.•The structural features…”
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Reprofiling of full‐length phosphonated carbocyclic 2′‐oxa‐3′‐aza‐nucleosides toward antiproliferative agents: Synthesis, antiproliferative activity, and molecular docking study
Published in Chemical biology & drug design (01-11-2017)“…A series of phosphonated carbocyclic 2′‐oxa‐3′‐aza‐nucleosides were synthesized via 1,3 dipolar cycloaddition and evaluated for their in vitro…”
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Preparation and biological evaluation of metronidazole derivatives with monoterpenes and eugenol
Published in Chemical biology & drug design (01-12-2018)“…Two series of metronidazole derivatives (ester derivatives and ether derivatives) were prepared reacting metronidazole and its acetic acid oxidized form with…”
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7
Atom and receptor based 3D QSAR models for generating new conformations from pyrazolopyrimidine as IL-2 inducible tyrosine kinase inhibitors
Published in Journal of molecular graphics & modelling (01-06-2017)“…[Display omitted] •The quantitative structure-activity relationship (QSAR) and molecular docking of pyrazolopyrimidines derivatives were investigated.•The…”
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Stability-indicating HPLC-DAD Method for Simultaneous Determination of Atorvastatin, Irbesartan, and Amlodipine in Bulk and Pharmaceutical Preparations
Published in Bulletin of the Korean Chemical Society (01-09-2015)“…The present study describes a convenient stability‐indicating HPLC‐DAD method for the separation and simultaneous determination of the drugs atorvastatin,…”
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9
Design and Synthesis of 4-O-Podophyllotoxin Sulfamate Derivatives as Potential Cytotoxic Agents
Published in Evidence-based complementary and alternative medicine (2021)“…4-O-Podophyllotoxin sulfamate derivatives were prepared using the natural lignan podophyllotoxin. The prepared compounds were afforded by reacting O-sulfonyl…”
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