Search Results - "Bjorksten, Andrew R."

Junctional membrane Ca2+ dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation by Cully, Tanya R., Choi, Rocky H., Bjorksten, Andrew R., Stephenson, D. George, Murphy, Robyn M., Launikonis, Bradley S.

“…We used the nanometer-wide tubules of the transverse tubular (t)-system of human skeletal muscle fibers as sensitive sensors for the quantitative monitoring of…”
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Comparative Plasma and Cerebrospinal Fluid Pharmacokinetics of Paracetamol After Intravenous and Oral Administration by Langford, Roger A., Hogg, Malcolm, Bjorksten, Andrew R., Williams, Daryl L., Leslie, Kate, Jamsen, Kris, Kirkpatrick, Carl

“…We compared plasma and cerebrospinal fluid (CSF) pharmacokinetics of paracetamol after intravenous (IV) and oral administration to determine dosing regimens…”
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N-acetylcysteine attenuates the decline in muscle Na+,K+-pump activity and delays fatigue during prolonged exercise in humans by McKenna, Michael J., Medved, Ivan, Goodman, Craig A., Brown, Malcolm J., Bjorksten, Andrew R., Murphy, Kate T., Petersen, Aaron C., Sostaric, Simon, Gong, Xiaofei

“…Reactive oxygen species (ROS) have been linked with both depressed Na + ,K + -pump activity and skeletal muscle fatigue. This study investigated N…”
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Generation of Adrenal Chromaffin-like Cells from Human Pluripotent Stem Cells by Abu-Bonsrah, Kwaku Dad, Zhang, Dongcheng, Bjorksten, Andrew R., Dottori, Mirella, Newgreen, Donald F.

“…Adrenomedullary chromaffin cells are catecholamine (CA)-producing cells originating from trunk neural crest (NC) via sympathoadrenal progenitors (SAPs). We…”
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Dexmedetomidine and meperidine additively reduce the shivering threshold in humans by DOUFAS, Anthony G, LIN, Chun-Ming, SULEMAN, Mohammad-Irfan, LIEM, Edwin B, LENHARDT, Rainer, MORIOKA, Nobutada, AKCA, Ozan, SHAH, Yunus M, BJORKSTEN, Andrew R, SESSLER, Daniel I

“…Hypothermia might prove to be therapeutically beneficial in stroke victims; however, even mild hypothermia provokes vigorous shivering. Meperidine and…”
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Induction speed is not a determinant of propofol pharmacodynamics by DOUFAS, Anthony G, BAKHSHANDEH, Maryam, BJORKSTEN, Andrew R, SHAFER, Steven L, SESSLER, Daniel I

“…Evidence suggests that the rate at which intravenous anesthetics are infused may influence their plasma-effect site equilibration. The authors used five…”
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Effects of intravenous N-acetylcysteine infusion on time to fatigue and potassium regulation during prolonged cycling exercise by Medved, Ivan, Brown, Malcolm J, Bjorksten, Andrew R, McKenna, Michael J

“…1 Muscle, Ions and Exercise Group, School of Human Movement, Recreation and Performance, Centre for Rehabilitation, Exercise and Sport Science, Victoria…”
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Meperidine decreases the shivering threshold twice as much as the vasoconstriction threshold by KURZ, A, IKEDA, T, SESSLER, D. I, LARSON, M. D, BJORKSTEN, A. R, DECHERT, M, CHRISTENSEN, R

“…Meperidine administration is a more effective treatment for shivering than equianalgesic doses of other opioids. However, it remains unknown whether meperidine…”
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Peritumoural glutamate correlates with post-operative seizures in supratentorial gliomas by Neal, Andrew, Yuen, Tanya, Bjorksten, Andrew R., Kwan, Patrick, O’Brien, Terence J., Morokoff, Andrew

“…To examine the impact of glutamate on post-operative seizures and survival in a cohort of patients with grade II to IV supratentorial glioma. A retrospective…”
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Junctional membrane Ca 2+ dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation by Cully, Tanya R, Choi, Rocky H, Bjorksten, Andrew R, Stephenson, D George, Murphy, Robyn M, Launikonis, Bradley S

“…We used the nanometer-wide tubules of the transverse tubular (t)-system of human skeletal muscle fibers as sensitive sensors for the quantitative monitoring of…”
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Mild Core Hypothermia and Anesthetic Requirement for Loss of Responsiveness During Propofol Anesthesia for Craniotomy by Leslie, Kate, Bjorksten, Andrew R., Ugoni, Antony, Mitchell, Peter

“…Mild hypothermia may be induced during neurosurgery for brain protection. However, its effect on propofol requirement has not been defined. Accordingly, we…”
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The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells by Ching, Jared, Amiridis, Stephanie, Stylli, Stanley S, Bjorksten, Andrew R, Kountouri, Nicole, Zheng, Thomas, Paradiso, Lucy, Luwor, Rodney B, Morokoff, Andrew P, O'Brien, Terence J, Kaye, Andrew H

“…Glioma cells release glutamate through expression of system xc-, which exchanges intracellular glutamate for extracellular cysteine. Lack of the excitatory…”
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Automated responsiveness test (ART) predicts loss of consciousness and adverse physiologic responses during propofol conscious sedation by DOUFAS, Anthony G, BAKHSHANDEH, Maryam, BJORKSTEN, Andrew R, GREIF, Robert, SESSLER, Daniel I

“…The authors evaluated a device designed to provide conscious sedation with propofol (propofol-air), or propofol combined with 50% nitrous oxide (N2O;…”
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Absorption characteristics of epidural levobupivacaine with adrenaline and clonidine in children by Chalkiadis, George A., Abdullah, Farah, Bjorksten, Andrew R., Clarke, Alexander, Cortinez, Luis I., Udayasiri, Sonal, Anderson, Brian J.

“…Summary Aim To determine if the addition of adrenaline, clonidine, or their combination altered the pharmacokinetic profile of levobupivacaine administered via…”
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Buspirone and Meperidine Synergistically Reduce the Shivering Threshold by Mokhtarani, Masoud, Mahgoub, Adel N., Morioka, Nobutada, Doufas, Anthony G., Dae, Michael, Shaughnessy, Thomas E., Bjorksten, Andrew R., Sessler, Daniel I.

“…Mild hypothermia (i.e., 34°C) may prove therapeutic for patients with stroke, but it usually provokes shivering. We tested the hypothesis that the combination…”
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Automated Responsiveness Monitor to Titrate Propofol Sedation by Doufas, Anthony G., Morioka, Nobutada, Mahgoub, Adel N., Bjorksten, Andrew R., Shafer, Steven L., Sessler, Daniel I.

“…In previous studies, we showed that failure to respond to automated responsiveness monitor (ARM) precedes potentially serious sedation-related adversities…”
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Mild Hypothermia Alters Propofol Pharmacokinetics and Increases the Duration of Action of Atracurium by Leslie, Kate, Sessler, Daniel I., Bjorksten, Andrew R., Moayeri, Azita

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Nitrous Oxide and Anesthetic Requirement for Loss of Response to Command During Propofol Anesthesia by Karalapillai, Dharshi, Leslie, Kate, Umranikar, Abhay, Bjorksten, Andrew R.

“…The blood concentration associated with loss of response (LOR) to command in 50% of subjects (CP50LOR) is an important measure of anesthetic potency. We…”
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Propofol linearly reduces the vasoconstriction and shivering thresholds by MATSUKAWA, T, KURZ, A, SESSLER, D. I, BJORKSTEN, A. R, MERRIFIELD, B, CHENG, C

“…Skin temperature is best kept constant when determining response thresholds because both skin and core temperatures contribute to thermoregulatory control. In…”
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Alfentanil slightly increases the sweating threshold and markedly reduces the vasoconstriction and shivering thresholds by KURZ, A, GO, J. C, SESSLER, D. I, KAER, K, LARSON, M. D, BJORKSTEN, A. R

“…Hypothermia is common in surgical patients and victims of major trauma; it also results from environmental exposure and drug abuse. In most cases, hypothermia…”
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