Search Results - "Björkman, S. Tracey"
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Review: The blood-brain barrier; protecting the developing fetal brain
Published in Placenta (Eastbourne) (01-06-2017)“…Abstract While placental function is fundamental to normal fetal development, the blood-brain barrier provides a second checkpoint critical to protecting the…”
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Cytoskeletal Anchoring of GLAST Determines Susceptibility to Brain Damage: AN IDENTIFIED ROLE FOR GFAP
Published in The Journal of biological chemistry (05-10-2007)“…Glial fibrillary acidic protein (GFAP) is an enigmatic protein; it currently has no unambiguously defined role. It is expressed in the cytoskeleton of…”
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3
Morphological changes in white matter astrocytes in response to hypoxia/ischemia in the neonatal pig
Published in Brain research (10-03-2010)“…Abstract White matter damage is a significant problem in the human pre-term baby. Damage to white matter is usually associated with injury or insults to babies…”
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Neonatal seizures and disruption to neurotransmitter systems
Published in Neural regeneration research (01-02-2017)“…Seizure disorders and epilepsies are well documented to be associated with long-term neurological and cognitive deficits in the adult and pediatric…”
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Hypoxic/ischemic models in newborn piglet : Comparison of constant FiO2 versus variable FiO2 delivery
Published in Brain research (19-07-2006)“…A comparison of a constant (continuous delivery of 4% FiO2) and a variable (initial 5% FiO2 with adjustments to induce low amplitude EEG (LAEEG) and…”
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Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain
Published in Journal of neuroinflammation (08-01-2019)“…The fetal brain is particularly vulnerable to intrauterine growth restriction (IUGR) conditions evidenced by neuronal and white matter abnormalities and…”
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Early evolution of glial morphology and inflammatory cytokines following hypoxic-ischemic injury in the newborn piglet brain
Published in Scientific reports (06-01-2023)“…Neuroinflammation is a hallmark of hypoxic-ischemic injury and can be characterized by the activation of glial cells and the expression of inflammatory…”
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Therapeutic potential to reduce brain injury in growth restricted newborns
Published in The Journal of physiology (01-12-2018)“…Brain injury in intrauterine growth restricted (IUGR) infants is a major contributing factor to morbidity and mortality worldwide. Adverse outcomes range from…”
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Ibuprofen Treatment Reduces the Neuroinflammatory Response and Associated Neuronal and White Matter Impairment in the Growth Restricted Newborn
Published in Frontiers in physiology (10-05-2019)“…Intrauterine growth restriction (IUGR) is a condition where the fetus does not achieve optimal growth, commonly caused by placental insufficiency. The chronic…”
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Editorial: Pathomechanisms and Treatments to Protect the Preterm, Fetal Growth Restricted and Neonatal Encephalopathic Brain
Published in Frontiers in neurology (09-09-2021)Get full text
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Identification and expression of a unique neonatal variant of the GABAA receptor α3 subunit
Published in Brain Structure and Function (01-03-2018)“…The GABA A receptor provides the majority of inhibitory neurotransmission in the adult central nervous system but in immature brain is responsible for much of…”
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Phosphorylation of GFAP is Associated with Injury in the Neonatal Pig Hypoxic-Ischemic Brain
Published in Neurochemical research (01-11-2012)“…Glial fibrillary acidic protein (GFAP) is an intermediate filament protein expressed in the astrocyte cytoskeleton that plays an important role in the…”
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Structural remodeling of gray matter astrocytes in the neonatal pig brain after hypoxia/ischemia
Published in Glia (15-01-2010)“…Astrocytes play a vital role in the brain; their structural integrity and sustained function are essential for neuronal viability, especially after injury or…”
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Review: Neuroinflammation in intrauterine growth restriction
Published in Placenta (Eastbourne) (01-06-2017)“…Abstract Disruption to the maternal environment during pregnancy from events such as hypoxia, stress, toxins, inflammation, and reduced placental blood flow…”
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Regional Expression of Dopamine D 1 and D 2 Receptor Proteins in the Cerebral Cortex of Asphyxic Newborn Infants
Published in Journal of child neurology (01-02-2009)“…Dopamine D 1 and D 2 receptor protein expression was examined by Western blotting in newborn infants dying from cerebral asphyxia between 31 and 42 weeks'…”
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Combined hypothermia and mesenchymal stem cells in animal models of neonatal hypoxic–ischaemic encephalopathy: a systematic review
Published in Pediatric research (01-07-2022)“…Background The objective of this study was to systematically review the literature to determine the effect of combined hypothermia (HTH) and mesenchymal stem…”
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Regional Expression of Dopamine D1 and D2 Receptor Proteins in the Cerebral Cortex of Asphyxic Newborn Infants
Published in Journal of child neurology (01-02-2009)“…Dopamine D1 and D2 receptor protein expression was examined by Western blotting in newborn infants dying from cerebral asphyxia between 31 and 42 weeks'…”
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Neonatal seizures are associated with redistribution and loss of GABAA α‐subunits in the hypoxic‐ischaemic pig
Published in Journal of neurochemistry (01-11-2016)“…Seizures are a common manifestation of hypoxic‐ischaemic brain injury in the neonate. In status epilepticus models alterations to GABAAR subunit expression…”
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19
Cytoskeletal Anchoring of GLAST Determines Susceptibility to Brain Damage
Published in The Journal of biological chemistry (05-10-2007)“…Glial fibrillary acidic protein (GFAP) is an enigmatic protein; it currently has no unambiguously defined role. It is expressed in the cytoskeleton of…”
Get full text
Journal Article -
20
Neonatal seizures are associated with redistribution and loss of GABA A α-subunits in the hypoxic-ischaemic pig
Published in Journal of neurochemistry (01-11-2016)“…Seizures are a common manifestation of hypoxic-ischaemic brain injury in the neonate. In status epilepticus models alterations to GABA R subunit expression…”
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