Performance of the Mood Disorder Questionnaire (MDQ) according to bipolar subtype and symptom severity

Abstract Objective To evaluate the performance of the French version of the Mood Disorder Questionnaire (MDQ) in patients attending a general psychiatric outpatient service as well as whether MDQ scores are independent of patient mood state at time of completion. Method 183 patients completed the MD...

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Bibliographic Details
Published in:	European psychiatry Vol. 24; no. 5; pp. 341 - 344
Main Authors:	Gervasoni, Nicola, Weber Rouget, Béatrice, Miguez, Mélissa, Dubuis, Vesselin, Bizzini, Vera, Gex-Fabry, Marianne, Bondolfi, Guido, Aubry, Jean-Michel
Format:	Journal Article
Language:	English
Published:	Paris Elsevier SAS 01-06-2009 Elsevier
Subjects:	Adult Biological and medical sciences Bipolar disorder Bipolar Disorder - classification Bipolar Disorder - diagnosis Bipolar Disorder - psychology Depression Depressive Disorder - diagnosis Depressive Disorder - psychology Diagnosis Diagnosis, Differential Female Humans Hypomania Internal Medicine Male Medical sciences Middle Aged Personality Inventory - statistics & numerical data Psychiatry Psychology. Psychoanalysis. Psychiatry Psychometrics - statistics & numerical data Psychometrics. Diagnostic aid systems Psychopathology. Psychiatry Questionnaires Reproducibility of Results Techniques and methods Young Adult Bipolar disorder Depression Diagnosis Hypomania Questionnaires Human Mood disorder Foreign language version Questionnaire Internal consistency Psychometrics Test reliability Intertrial interval Test validation Symptomatology French Follow up study Severity score Subtype Predictive validity
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Summary:	Abstract Objective To evaluate the performance of the French version of the Mood Disorder Questionnaire (MDQ) in patients attending a general psychiatric outpatient service as well as whether MDQ scores are independent of patient mood state at time of completion. Method 183 patients completed the MDQ and were assessed with the MADRS and YMRS scales, before being interviewed with the SCID (time 1). MDQ, MADRS and YMRS assessment was repeated four to six weeks later (time 2). Results According to the SCID, 44 patients were suffering from bipolar spectrum disorder and 102 from unipolar disorder (37 patients dropped out). The MDQ provided high specificity (83.3%). Sensitivity was 63.6%, with better identification of bipolar I (85.0%) than bipolar II patients (45.8%). In the whole sample, test-retest reliability was satisfactory (kappa = 0.64). Modest correlations were observed between the number of endorsed MDQ items and YMRS scores at time 1 (Spearman r = 0.19; p = 0.021) and time 2 (r = 0.26; p = 0.002). Conclusions Despite some fluctuations over time and a discrete influence of symptom severity, the screening algorithm can be used reliably, whether in the acute or remission phase of a depressive episode.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0924-9338 1778-3585
DOI:	10.1016/j.eurpsy.2008.12.008