Search Results - "Bixler, A."

BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF by Thompson, Jeffrey S., Bixler, Sarah A., Qian, Fang, Vora, Kalpit, Scott, Martin L., Cachero, Teresa G., Hession, Catherine, Schneider, Pascal, Sizing, Irene D., Mullen, Colleen, Strauch, Kathy, Zafari, Mohammad, Benjamin, Christopher D., Tschopp, Jurg, Browning, Jeffrey L., Ambrose, Christine

“…B cell homeostasis has been shown to critically depend on BAFF, the B cell activation factor from the tumor necrosis factor (TNF) family. Although BAFF is…”
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BAFF selectively enhances the survival of plasmablasts generated from human memory B cells by Avery, Danielle T, Kalled, Susan L, Ellyard, Julia I, Ambrose, Christine, Bixler, Sarah A, Thien, Marilyn, Brink, Robert, Mackay, Fabienne, Hodgkin, Philip D, Tangye, Stuart G

“…The generation of Ig-secreting cells (ISCs) from memory B cells requires interactions between antigen-specific (Ag-specific) B cells, T cells, and dendritic…”
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BAFF selectively enhances the survival of plasmablasts generated from human memory B cells by Avery, Danielle T., Kalled, Susan L., Ellyard, Julia I., Ambrose, Christine, Bixler, Sarah A., Thien, Marilyn, Brink, Robert, Mackay, Fabienne, Hodgkin, Philip D., Tangye, Stuart G.

“…The generation of Ig-secreting cells (ISCs) from memory B cells requires interactions between antigen-specific (Ag-specific) B cells, T cells, and dendritic…”
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Sex-specific frontal-striatal connectivity differences among adolescents with externalizing disorders by Chai, Ya, Chimelis-Santiago, José R., Bixler, Kristy A., Aalsma, Matthew, Yu, Meichen, Hulvershorn, Leslie A.

“…•Boys had higher impulsivity scores than girls with externalizing disorders.•Boys showed greater ventromedial prefrontal-ventral striatal connectivity than…”
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User-Guided Enhancements to a Technology-Facilitated Resilience Program to Address Opioid Risks Following Traumatic Injury in Youth: Qualitative Interview Study by Adams, Zachary W, Marriott, Brigid R, Karra, Swathi, Linhart-Musikant, Elizabeth, Raymond, Jodi L, Fischer, Lydia J, Bixler, Kristina A, Bell, Teresa M, Bryan, Eric A, Hulvershorn, Leslie A

“…Youth with traumatic injury experience elevated risk for behavioral health disorders, yet posthospital monitoring of patients' behavioral health is rare. The…”
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Accuracy of noncycloplegic retinoscopy, retinomax autorefractor, and SureSight vision screener for detecting significant refractive errors by Kulp, Marjean Taylor, Ying, Gui-Shuang, Huang, Jiayan, Maguire, Maureen, Quinn, Graham, Ciner, Elise B, Cyert, Lynn A, Orel-Bixler, Deborah A, Moore, Bruce D

“…To evaluate, by receiver operating characteristic (ROC) analysis, the ability of noncycloplegic retinoscopy (NCR), Retinomax Autorefractor (Retinomax), and…”
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EC144 Is a Potent Inhibitor of the Heat Shock Protein 90 by Shi, Jiandong, Van de Water, Ryan, Hong, Kevin, Lamer, Ryan B, Weichert, Kenneth W, Sandoval, Cristina M, Kasibhatla, Srinivas R, Boehm, Marcus F, Chao, Jianhua, Lundgren, Karen, Timple, Noelito, Lough, Rachel, Ibanez, Gerardo, Boykin, Christina, Burrows, Francis J, Kehry, Marilyn R, Yun, Theodore J, Harning, Erin K, Ambrose, Christine, Thompson, Jeffrey, Bixler, Sarah A, Dunah, Anthone, Snodgrass-Belt, Pamela, Arndt, Joseph, Enyedy, Istvan J, Li, Ping, Hong, Victor S, McKenzie, Andres, Biamonte, Marco A

“…Alkyne 40, 5-(2-amino-4-chloro-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methylpent-4-yn-2-ol (EC144), is a second…”
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Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF by Jacob, Chaim O, Pricop, Luminita, Putterman, Chaim, Koss, Michael N, Liu, Yi, Kollaros, Maria, Bixler, Sarah A, Ambrose, Christine M, Scott, Martin L, Stohl, William

“…Constitutive overexpression of B cell-activating factor belonging to the TNF family (BAFF) promotes development of systemic lupus erythematosus (SLE), and…”
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Cutting Edge: BAFF Regulates CD21/35 and CD23 Expression Independent of Its B Cell Survival Function by Gorelik, Leonid, Cutler, Anne H, Thill, Greg, Miklasz, Steven D, Shea, Dianna E, Ambrose, Christine, Bixler, Sarah A, Su, Lihe, Scott, Martin L, Kalled, Susan L

“…Herein we demonstrate that B cell-activating factor of the TNF family (BAFF), a B cell survival factor, also regulates CD21/35 and CD23 expression. BAFF…”
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Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog by Pepinsky, R. Blake, Zeng, Chenhui, Wen, Dingyi, Rayhorn, Paul, Baker, Darren P., Williams, Kevin P., Bixler, Sarah A., Ambrose, Christine M., Garber, Ellen A., Miatkowski, Konrad, Taylor, Frederick R., Wang, Elizabeth A., Galdes, Alphonse

“…During hedgehog biosynthesis, autocatalytic processing produces a lipid-modified amino-terminal fragment (residues 24–197 in the human Sonic hedgehog sequence)…”
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BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population by Thompson, J S, Schneider, P, Kalled, S L, Wang, L, Lefevre, E A, Cachero, T G, MacKay, F, Bixler, S A, Zafari, M, Liu, Z Y, Woodcock, S A, Qian, F, Batten, M, Madry, C, Richard, Y, Benjamin, C D, Browning, J L, Tsapis, A, Tschopp, J, Ambrose, C

“…The tumor necrosis factor (TNF) family member B cell activating factor (BAFF) binds B cells and enhances B cell receptor-triggered proliferation. We find that…”
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Effectiveness of safety training interventions for supervisors: A systematic review and narrative synthesis by Sinelnikov, Sergey, Bixler, Emily A., Kolosh, Alaina

“…A wealth of research demonstrates that work unit supervisors serve a critical function in protecting the safety and health of workers. A systematic review…”
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Cytologic differentiation of squamous elements in the pancreas by Bixler, Heather A., Castro, Michael J., Stewart III, Jimmie

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Comparison of Soluble Decoy IgG Fusion Proteins of BAFF-R and BCMA as Antagonists for BAFF by Pelletier, Marc, Thompson, Jeffrey S., Qian, Fang, Bixler, Sarah A., Gong, Dahai, Cachero, Teresa, Gilbride, Kevin, Day, Eric, Zafari, Mohammad, Benjamin, Chris, Gorelik, Leonid, Whitty, Adrian, Kalled, Susan L., Ambrose, Christine, Hsu, Yen-Ming

“…BAFF is considered a therapeutic target because dysregulated production of BAFF can induce systemic lupus erythematosus-like phenotype in mice, and elevated…”
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Comprehensive Workplace Policies and Practices Regarding Employee Opioid Use by Cooper, Rachael, Bixler, Emily A.

“…The workplace is a key environment to impact employees, families, and communities to prevent further opioid and substance misuse, addiction, and overdose…”
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Prescription opioid misuse among adolescents and emerging adults in the United States: A scoping review by Bonar, Erin E., Coughlin, Lara, Roche, Jessica S., Philyaw-Kotov, Meredith L., Bixler, Emily A., Sinelnikov, Sergey, Kolosh, Alaina, Cihak, Morgan J., Cunningham, Rebecca M., Walton, Maureen A.

“…The U.S. opioid epidemic is a critical public health problem. As substance use and misuse typically begin in adolescence and emerging adulthood, there is a…”
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Associations between Hyperopia and Other Vision and Refractive Error Characteristics by Kulp, Marjean Taylor, Ying, Gui-shuang, Huang, Jiayan, Maguire, Maureen, Quinn, Graham, Ciner, Elise B, Cyert, Lynn A, Orel-Bixler, Deborah A, Moore, Bruce D

“…PURPOSETo investigate the association of hyperopia greater than +3.25 diopters (D) with amblyopia, strabismus, anisometropia, astigmatism, and reduced…”
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Chemical deacylation reduces the adhesive properties of proteolipid protein and leads to decompaction of the myelin sheath by Bizzozero, Oscar A., Bixler, Heather A., Davis, Judi D., Espinosa, Araceli, Messier, Amber M.

“…Myelin proteolipid protein (PLP) contains thioester‐bound, long‐chain fatty acids which are known to influence the structure of the molecule. To gain further…”
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Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses by MILLER, G. T, HOCHMAN, P. S, MEIER, W, TIZARD, R, BIXLER, S. A, ROSA, M. D, WALLNER, B. P

“…Accessory cell surface molecules, such as T cell antigen CD2 and its ligand lymphocyte function-associated antigen 3 (LFA-3; CD58), are critical costimulatory…”
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Induced Fit Activation Mechanism of the Exceptionally Specific Serine Protease, Complement Factor D by Taylor, Frederick R, Bixler, Sarah A, Budman, Joe I, Wen, Dingyi, Karpusas, Michael, Ryan, Sarah T, Jaworski, Gary J, Safari-Fard, Abbas, Pollard, Stuart, Whitty, Adrian

“…We have investigated the mechanism by which the complement protease, Factor D, achieves its high specificity for the cleavage of Factor B in complex with…”
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