Search Results - "Biunno, Ida"

New Challenges for Biobanks: Accreditation to the New ISO 20387:2018 Standard Specific for Biobanks by De Blasio, Pasquale, Biunno, Ida

“…Background: The emergence of “multi-omics” and “multi-parametric” types of analysis based on a high number of biospecimens enforces the use of a great number…”
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Trehalose to cryopreserve human pluripotent stem cells by Ntai, Aikaterini, La Spada, Alberto, De Blasio, Pasquale, Biunno, Ida

“…The successful exploitation of human pluripotent stem cells (hPSCs) for research, translational or commercial reasons requires the implementation of a simple…”
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Human sample authentication in biomedical research: comparison of two platforms by Manjunath, Harshitha Shobha, James, Nicola, Mathew, Rebecca, Al Hashmi, Muna, Silcock, Lee, Biunno, Ida, De Blasio, Pasquale, Manickam, Chidambaram, Tomei, Sara

“…Samples used in biomedical research are often collected over years, in some cases from subjects that may have died and thus cannot be retrieved in any way. The…”
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Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients by Di Buduo, Christian A, Laurent, Pierre-Alexandre, Zaninetti, Carlo, Lordier, Larissa, Soprano, Paolo M, Ntai, Aikaterini, Barozzi, Serena, La Spada, Alberto, Biunno, Ida, Raslova, Hana, Bussel, James B, Kaplan, David L, Balduini, Carlo L, Pecci, Alessandro, Balduini, Alessandra

“…Thrombocytopenic disorders have been treated with the Thrombopoietin-receptor agonist Eltrombopag. Patients with the same apparent form of thrombocytopenia may…”
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ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis by Basso-Valentina, Francesca, Donada, Alessandro, Manchev, Vladimir T, Lisetto, Manuel, Balayn, Nathalie, Martin, Jean Edouard, Muller, Delphine, Oyarzun, Cecilia Paola Marin, Duparc, Hélène, Arkoun, Brahim, Cumin, Alessandro, Faivre, Lionel, Droin, Nathalie, Biunno, Ida, Pecci, Alessandro, Balduini, Alessandra, Debili, Najet, Antony-Debré, Iléana, Marty, Caroline, Vainchenker, William, Plo, Isabelle, Favier, Remi, Raslova, Hana

“…Sustained ANKRD26 expression associated with germline ANKRD26 mutations causes thrombocytopenia 2 (THC2), an inherited platelet disorder associated with a…”
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The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity by Camnasio, Stefano, Carri, Alessia Delli, Lombardo, Angelo, Grad, Iwona, Mariotti, Caterina, Castucci, Alessia, Rozell, Björn, Riso, Pietro Lo, Castiglioni, Valentina, Zuccato, Chiara, Rochon, Christelle, Takashima, Yasuhiro, Diaferia, Giuseppe, Biunno, Ida, Gellera, Cinzia, Jaconi, Marisa, Smith, Austin, Hovatta, Outi, Naldini, Luigi, Di Donato, Stefano, Feki, Anis, Cattaneo, Elena

“…Abstract Neuronal disorders, like Huntington's disease (HD), are difficult to study, due to limited cell accessibility, late onset manifestations, and low…”
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SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling by Diaferia, Giuseppe R, Cirulli, Vincenzo, Biunno, Ida

“…SEL1L, a component of the endoplasmic reticulum associated degradation (ERAD) pathway, has been reported to regulate the (i) differentiation of the pancreatic…”
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Delineating the cytogenomic and epigenomic landscapes of glioma stem cell lines by Baronchelli, Simona, Bentivegna, Angela, Redaelli, Serena, Riva, Gabriele, Butta, Valentina, Paoletta, Laura, Isimbaldi, Giuseppe, Miozzo, Monica, Tabano, Silvia, Daga, Antonio, Marubbi, Daniela, Cattaneo, Monica, Biunno, Ida, Dalprà, Leda

“…Glioblastoma multiforme (GBM), the most common and malignant type of glioma, is characterized by a poor prognosis and the lack of an effective treatment, which…”
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Additional congeners of the macrolide neaumycin: structure revision and biological activity by Simone, Matteo, Maffioli, Sonia I, Tocchetti, Arianna, Tretter, Stefano, Cattaneo, Monica, Biunno, Ida, Gaspari, Eleonora, Donadio, Stefano

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Deficiency of Suppressor Enhancer Lin12 1 Like (SEL1L) in Mice Leads to Systemic Endoplasmic Reticulum Stress and Embryonic Lethality by Francisco, Adam B., Singh, Rajni, Li, Shuai, Vani, Anish K., Yang, Liu, Munroe, Robert J., Diaferia, Giuseppe, Cardano, Marina, Biunno, Ida, Qi, Ling, Schimenti, John C., Long, Qiaoming

“…Stress in the endoplasmic reticulum (ER) plays an important causal role in the pathogenesis of several chronic diseases such as Alzheimer, Parkinson, and…”
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Down-modulation of SEL1L, an Unfolded Protein Response and Endoplasmic Reticulum-associated Degradation Protein, Sensitizes Glioma Stem Cells to the Cytotoxic Effect of Valproic Acid by Cattaneo, Monica, Baronchelli, Simona, Schiffer, Davide, Mellai, Marta, Caldera, Valentina, Saccani, Gloria Jotti, Dalpra, Leda, Daga, Antonio, Orlandi, Rosaria, DeBlasio, Pasquale, Biunno, Ida

“…Valproic acid (VPA), an histone deacetylase inhibitor, is emerging as a promising therapeutic agent for the treatments of gliomas by virtue of its ability to…”
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Correction: SEL1L Regulates Adhesion, Proliferation and Secretion of Insulin by Affecting Integrin Signaling by Diaferia, Giuseppe R., Cirulli, Vincenzo, Biunno, Ida

“…G. R. Diaferia was the recipient of a Postdoctoral fellowship from the Juvenile Diabetes Research Foundation. V. Cirulli was supported by an American Diabetes…”
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SEL1L plays a major role in human malignant gliomas by Mellai, Marta, Annovazzi, Laura, Boldorini, Renzo, Bertero, Luca, Cassoni, Paola, De Blasio, Pasquale, Biunno, Ida, Schiffer, Davide

“…Suppressor of Lin‐12‐like (C. elegans) (SEL1L) participates in the endoplasmic reticulum‐associated protein degradation pathway, malignant transformation and…”
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Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells by Cattaneo, Monica, Lotti, Lavinia Vittoria, Martino, Simone, Alessio, Massimo, Conti, Antonio, Bachi, Angela, Mariani-Costantini, Renato, Biunno, Ida

“…We describe here two novel endogenous variants of the human endoplasmic reticulum (ER) cargo receptor SEL1LA, designated p38 and p28. Biochemical and RNA…”
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In vitro anticancer drug test: A new method emerges from the model of glioma stem cells by Riva, Gabriele, Baronchelli, Simona, Paoletta, Laura, Butta, Valentina, Biunno, Ida, Lavitrano, Marialuisa, Dalprà, Leda, Bentivegna, Angela

“…Glioblastoma multiforme (GBM) is a grade IV astrocytoma and the most common malignant brain tumor. Current therapies provide a median survival of 12-15 months…”
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Functional Characterization of Two Secreted SEL1L Isoforms Capable of Exporting Unassembled Substrate by Cattaneo, Monica, Lotti, Lavinia Vittoria, Martino, Simone, Cardano, Marina, Orlandi, Rosaria, Mariani-Costantini, Renato, Biunno, Ida

“…SEL1L-A, a transmembrane glycoprotein residing in the endoplasmic reticulum (ER), is a component of the ER-associated degradation (ERAD) pathway. Alternative…”
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SEL1L a multifaceted protein playing a role in tumor progression by Biunno, Ida, Cattaneo, Monica, Orlandi, Rosaria, Canton, Cristina, Biagiotti, Laura, Ferrero, Stefano, Barberis, Massimo, Pupa, Serenella M., Scarpa, Aldo, Ménard, Sylvie

“…Since the cloning in 1997 of SEL1L, the human ortholog of the sel‐1 gene of C. elegans, most studies have focused on its role in cancer progression and have…”
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SEL1L Affects Human Pancreatic Cancer Cell Cycle and Invasiveness through Modulation of PTEN and Genes Related to Cell-Matrix Interactions by Cattaneo, Monica, Fontanella, Enrico, Canton, Cristina, Delia, Domenico, Biunno, Ida

“…Previously, it was reported that SEL1L is able to decrease the aggressive behavior of human pancreatic tumor cells both in vitro and in vivo. To gain insights…”
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SEL1L and Squamous Cell Carcinoma of the Esophagus by GRANELLI, Paola, CATTANEO, Monica, FERRERO, Stefano, BOTTIGLIERI, Luca, BOSARI, Silvano, FICHERA, Giuseppe, BIUNNO, Ida

“…The gene SEL1L is involved both in human breast and pancreatic cancer progression. It is located on 14q24.3–31, a region known to be lost in invasive cancer of…”
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The Application of the Tissue Microarray (TMA) Technology to Analyze Cerebral Organoids by Biunno, Ida, Paiola, Emanuela, De Blasio, Pasquale

“…“Multi-Omics” technologies have contributed greatly to the understanding of various diseases by enabling researchers to accurately and rapidly investigate the…”
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