Search Results - "Bittner, Stephen E"
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Effects of SC-56525, a Potent, Orally Active Renin Inhibitor, in Salt-Depleted and Renal Hypertensive Dogs
Published in Hypertension (Dallas, Tex. 1979) (01-07-1995)“…SC-56525 is a nanomolar inhibitor of plasma renin activity in human, cynomolgus monkey, dog, guinea pig, Yucatan micropig, and rabbit but is less active in…”
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2
Effects of a high-dose treatment of methamphetamine on caudate dopamine and anorexia in rats
Published in Pharmacology, biochemistry and behavior (01-04-1981)“…Dose-effect curves of d-methamphetamine (MA) on intake of sweetened condensed milk by rats were obtained before and after twice a day treatment for four days…”
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3
Simultaneous determination of ventricular function and systemic hemodynamics in the conscious rat
Published in Journal of pharmacological methods (01-05-1988)“…This study describes a method that utilizes a combination of the Millar transducer and Columbus thermistor in the conscious, spontaneously hypertensive rat and…”
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4
A new class of orally active glycol renin inhibitors containing phenyllactic acid at P3
Published in Biochemical and biophysical research communications (14-04-1989)“…We prepared a new series of renin inhibitors based on dipeptide glycols, replacing the P4-P3 subsites with an O-(N-morpholinocarbonyl)-3-L-phenyllactic acid…”
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5
Enhanced potency dipeptide glycol renin inhibitors: studies in vitro and in the conscious rhesus
Published in Biochemical and biophysical research communications (14-08-1987)“…We prepared a series of novel dipeptide amides of the formula Boc-Phe-Leu-X, where X is a 3-amino-3-alkyl-1,2-propanediol with lower alkyl substitutions at…”
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6
Dipeptide glycols: a new class of renin inhibitors
Published in Biochemical and biophysical research communications (15-10-1985)“…The discovery of a new class of novel renin inhibitors consisting of protected dipeptide amides derived from aminoglycols (Formula I) prompted a study of…”
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7
Cardiovascular effects of chronic high-dose atriopeptin III infusion in normotensive rats
Published in Toxicology and applied pharmacology (01-12-1987)“…Seventy-eight Sprague-Dawley rats received continuous intravenous infusions of either atriopeptin III (APIII), 60 micrograms/kg/hr, or distilled water vehicle…”
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