Search Results - "Bittner, G D"

The curious ability of polyethylene glycol fusion technologies to restore lost behaviors after nerve severance by Bittner, G.D., Sengelaub, D.R., Trevino, R.C., Peduzzi, J.D., Mikesh, M., Ghergherehchi, C.L., Schallert, T., Thayer, W.P.

“…Traumatic injuries to PNS and CNS axons are not uncommon. Restoration of lost behaviors following severance of mammalian peripheral nerve axons (PNAs) relies…”
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Polyethylene glycol-fused allografts produce rapid behavioral recovery after ablation of sciatic nerve segments by Riley, D.C., Bittner, G.D., Mikesh, M., Cardwell, N.L., Pollins, A.C., Ghergherehchi, C.L., Bhupanapadu Sunkesula, S.R., Ha, T.N., Hall, B.T.D., Poon, A.D., Pyarali, M., Boyer, R.B., Mazal, A.T., Munoz, N., Trevino, R.C., Schallert, T., Thayer, W.P.

“…Restoration of neuronal functions by outgrowths regenerating at ∼1 mm/day from the proximal stumps of severed peripheral nerves takes many weeks or months, if…”
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Robinson and madison have published no data on whether polyethylene glycol fusion repair prevents reinnervation accuracy in rat peripheral nerve by Bittner, G.D., Sengelaub, D.R., Trevino, R.C., Ghergherehchi, C.L., Mikesh, M.

“…Polyethylene glycol (PEG)-fusion technologies have been reported to rapidly, effectively, and permanently restore lost behavioral functions within days to…”
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Cellular mechanisms of plasmalemmal sealing and axonal repair by polyethylene glycol and methylene blue by Spaeth, C.S., Robison, T., Fan, J.D., Bittner, G.D.

“…Mammalian neurons and all other eukaryotic cells endogenously repair traumatic injury within minutes by a Ca2+‐induced accumulation of vesicles that interact…”
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Rapid, effective, and long-lasting behavioral recovery produced by microsutures, methylene blue, and polyethylene glycol after completely cutting rat sciatic nerves by Bittner, G.D., Keating, C.P., Kane, J.R., Britt, J.M., Spaeth, C.S., Fan, J.D., Zuzek, A., Wilcott, R.W., Thayer, W.P., Winograd, J.M., Gonzalez-Lima, F., Schallert, T.

“…Behavioral function lost in mammals (including humans) after peripheral nerve severance is slowly (weeks to years) and often poorly restored by 1–2‐mm/day,…”
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Neurite transection produces cytosolic oxidation, which enhances plasmalemmal repair by Spaeth, C.S., Fan, J.D., Spaeth, E.B., Robison, T., Wilcott, R.W., Bittner, G.D.

“…To survive, cells must rapidly repair (seal) plasmalemmal damage. Cytosolic oxidation has been shown to increase cell survival in some cases and produce cell…”
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Cyclosporin A Retards the Wallerian Degeneration of Peripheral Mammalian Axons by Sunio, Arisa, Bittner, George D.

“…The distal (anucleate) segments of mammalian peripheral axons typically undergo complete Wallerian degeneration within 1–3 days after severance from their cell…”
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Residual Free Calcium is not Responsible for Facilitation of Neurotransmitter Release by Blundon, Jay A., Wright, Sterling N., Brodwick, Malcolm S., Bittner, George D.

“…An increase in internal free calcium ([Ca2+]i) in the presynaptic terminal is often assumed to directly produce facilitation of neurotransmitter release. Using…”
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Presynaptic calcium-activated potassium channels and calcium channels at a crayfish neuromuscular junction by Blundon, J A, Wright, S N, Brodwick, M S, Bittner, G D

“…1. We used a two-microelectrode current clamp to investigate various characteristics of the Ca(2+)-activated K+ conductance [gK(Ca)] and Ca2+ conductance…”
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Rapid Morphological Fusion of Severed Myelinated Axons by Polyethylene Glycol by Krause, Todd L., Bittner, George D.

“…We are able to morphologically fuse the severed halves of an invertebrate-myelinated axon by application of polyethylene glycol (PEG) to closely apposed cut…”
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Calcium entry initiates processes that restore a barrier to dye entry in severed earthworm giant axons by Blanchette, Adam R, Ballinger, Martis L, Fishman, Harvey M, Bittner, George D

“…After severance, axons can restore structural barriers that are necessary for recovery of their electrical function. In earthworm myelinated axons, such a…”
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Effects of ethanol and other drugs on excitatory and inhibitory neurotransmission in the crayfish by Blundon, J A, Bittner, G D

“…1. Crayfish exposed to 434 mM ethanol (EtOH) showed signs of hyperactivity within 0.5-2 h, at which times crayfish hemolymph EtOH concentration had reached…”
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Medium weight neurofilament mRNA in goldfish Mauthner axoplasm by Weiner, Orion D., Zorn, Aaron M., Krieg, Paul A., Bittner, George D.

“…Although axons are generally considered to lack the ability to synthesize proteins, the Mauthner axon (M-axon) of the goldfish has been reported to contain…”
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Glia-to-axon communication: enrichment of glial proteins transferred to the squid giant axon by Sheller, R A, Tytell, M, Smyers, M, Bittner, G D

“…The transfer of newly synthesized proteins from the glial sheath into the axon is a well-documented process for the squid giant axon. In this study, we used a…”
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Calcium currents, transmitter release and facilitation of release at voltage-clamped crayfish nerve terminals by Wright, S N, Brodwick, M S, Bittner, G D

“…1. The presynaptic terminals at crayfish (Procambarus spp.) opener neuromuscular junctions were voltage clamped. Calcium currents were measured during (ICa)…”
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Plasmalemmal repair of severed neurites of PC12 cells requires Ca(2+) and synaptotagmin by Detrait, E R, Yoo, S, Eddleman, C S, Fukuda, M, Bittner, G D, Fishman, H M

“…Ca(2+) and synaptotagmin (a Ca(2+)-binding protein that regulates axolemmal fusion of synaptic vesicles) play essential roles in the repair of axolemmal damage…”
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Anomalies associated with dye exclusion as a measure of axolemmal repair in invertebrate axons by EDDLEMAN, C. S, SMYERS, M. E, LORE, A, FISHMAN, H. M, BITTNER, G. D

“…After axonal injury, dye exclusion is often used as a measure of the re-establishment of a structural barrier. We now report that this use of dye exclusion is…”
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Cooling of Peripheral Myelinated Axons Retards Wallerian Degeneration by Sea, Tia, Ballinger, Martis L., Bittner, George D.

“…The histological and ultrastructural status of intact and severed axons was examined in the ventral tail nerve of rats whose tails were maintained at 32, 23,…”
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Quantal Mechanism of Long-Term Synaptic Potentiation by Baxter, Douglas A., Bittner, George D., Brown, Thomas H.

“…Intracellular recordings were used to demonstrate the occurrence and to analyze the microphysiology of long-term synaptic potentiation (LTP) in the crayfish…”
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Phosphorylation of neurofilament proteins in isolated goldfish Mauthner axoplasm by Raabe, T D, Bittner, G D

“…The six neurofilament proteins (NFPs) in the goldfish Mauthner axon (M-axon) have molecular sizes of 235, 145, 123, 105, 80, and 60 kDa. To determine if NFPs…”
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