Search Results - "Bitla, Aparna R"

Effect of Rosuvastatin on Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Prospective Interventional Study by Thej, M Keerthi, Bitla, Aparna R, Rao, PVLNSrinivasa, Sachan, Alok

“…Introduction: Diabetes Mellitus (DM) is an established risk factor for Cardiovascular Disease (CVD). Oxidative Stress (OS) and inflammation are linked to CVD…”
Get full text

Attenuation of Oxidative Stress, Interleukin-6, High-Sensitivity C-Reactive Protein, Plasminogen Activator Inhibitor-1, and Fibrinogen with Oral Vitamin D Supplementation in Patients with T2DM having Vitamin D Deficiency by Pasupuleti, Pullaiah, Suchitra, M.M., Bitla, Aparna R., Sachan, Alok

“…Abstract Objectives Type 2 diabetes mellitus (T2DM) associated with oxidative stress and inflammation causes endothelial dysfunction, which promotes…”
Get full text

Serum Adenosine Deaminase as Inflammatory Marker in Rheumatoid Arthritis by Vinapamula, Kiranmayi S, Pemmaraju, Srinivasarao V L N, Bhattaram, Siddartha Kumar, Bitla, Aparna R, Manohar, Suchitra M

“…Rheumatoid arthritis (RA) is a prototypical inflammatory joint disease. The degree of inflammation is reflected in the extent of joint damage, which further…”
Get full text

Adipokines and their Relation to Endothelial Dysfunction in Patients with Chronic Kidney Disease by Ambarkar, Madhusudan, Pemmaraju, Srinivasarao V L N, Gouroju, Sivakrishna, Manohar, Suchitra M, Bitla, Aparna R, Yajamanam, Naresh, Vishnubhotla, Sivakumar

“…Chronic Kidney Disease (CKD) patients are at high risk of cardiovascular diseases (CVDs). Reduced nitric oxide (NO) bioavailability is a key element in…”
Get full text

Utility of saliva as a sample to assess renal function and estimated glomerular filtration rate by Yajamanam, Naresh, Bitla, Aparna R., Vinapamula, Kiranmayi S., Sivakumar, V., Rao, P. V. L. N. Srinivas

“…Diagnosis of renal diseases by assessing renal parameters in saliva. Biochemical investigations using serum form important component of monitoring patients…”
Get full text

Study of contrast-induced oxidative stress in nondiabetic patients undergoing coronary angiography by Vishnubhotla, Sivakumar, Rajasekhar, D., Vinapamula, Kiranmayi S., Bitla, Aparna R., Srinivasa Rao, P. V. L. N., Manda, Prasanth, Jeyaseelan, L.

“…Administration of iodinated contrast media is associated with serious compli- cations such as acute kidney injury (AKI). Oxidative stress is implicated as a…”
Get full text

Simultaneous determination of arginine, citrulline, and asymmetric dimethylarginine in plasma by reverse-phase high-performance liquid chromatography by Rao, P V L N Srinivasa, Bitla, Aparna R

“…Arginine, citrulline and asymmetric dimethylarginine (ADMA) are three molecules in the nitric oxide (NO) pathway which provide useful information about…”
Get full text

Evaluation of the effectiveness of critical result notification protocol of biochemistry laboratory at a tertiary care hospital by Thota, Silpa, Bitla, Aparna R.

“…Objectives: Critical value reporting is an essential aspect of laboratory medicine, ensuring prompt communication of life-threatening results to clinicians for…”
Get full text

In silico trials to design potent inhibitors against matrilysin (MMP-7) by Katari, Sudheer Kumar, Pasala, Chiranjeevi, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Umamaheswari, Amineni

“…The study deals with structure-based rational drug design against the chief zinc-rely endopeptidase called matrilysin (MMP-7) that is involved in inflammatory…”
Get full text

Epitope-driven common subunit vaccine design against H. pylori strains by Pasala, Chiranjeevi, Chilamakuri, Chandra Sekhar Reddy, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Amineni, Umamaheswari

“…The developing potent vaccine is a pre-emptive strategy to tackle drug abuses and maladies of multidrug-resistant Helicobacter pylori strains. Ongoing vaccine…”
Get full text

In silico probing exercises, bioactive-conformational and dynamic simulations strategies for designing and promoting selective therapeutics against Helicobacter pylori strains by Pasala, Chiranjeevi, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Amineni, Umamaheswari

“…A myriad of drug-resistant strains of Helicobacter pylori and adverse drug-reactions create a big-barrier in the treatment, thereby demanding novel…”
Get full text

Integration of core hopping, quantum-mechanics, molecular mechanics coupled binding-energy estimations and dynamic simulations for fragment-based novel therapeutic scaffolds against Helicobacter pylori strains by Pasala, Chiranjeevi, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Aparna, R. Bitla, Amineni, Umamaheswari

“…[Display omitted] •Experimental inhibitors were utilized for shape-screening using in-house library.•Substitutability endpoints of new scaffolds were…”
Get full text

Factor V Leiden mutation is not a predisposing factor for acute coronary syndromes by Himabindu, G, Rajasekhar, D, Latheef, K, Sarma, P.V.G.K, Vanajakshamma, V, Chaudhury, Abhijit, Bitla, Aparna R

“…Abstract Background The prevalence of Coronary artery disease (CAD) in India has increased considerably over the past few years and could become the number one…”
Get full text

The effect of l-carnitine supplementation on lipid parameters, inflammatory and nutritional markers in maintenance hemodialysis patients by Rao, P. V. L. N. Srinivas, Bitla, Aparna Rajeshwar Rao, Suchitra, M. M., Ashalatha, V. L., Sailaja, E., Rao, Ambarkar Madhusudhana, Sivakumar, V., Reddy, V. Sheshadri

“…Protein energy malnutrition and inflammation are common and usually concurrent in maintenance hemodialysis (MHD) patients. Carnitine, a small molecule involved…”
Get full text

Correction to: Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus by Naresh, Sriram, Bitla, Aparna R., Rao, P. V. L. N. Srinivasa, Sachan, Alok, Amancharla, Yadagiri Lakshmi

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus by Naresh, Sriram, Bitla, Aparna R., Rao, P. V. L. N. Srinivasa, Sachan, Alok, Amancharla, Yadagiri Lakshmi

“…Purpose High-density lipoprotein (HDL) undergoes structural and functional modification in patients with type 2 diabetes mellitus (T2DM). There are limited…”
Get full text

An in silico study: Novel targets for potential drug and vaccine design against drug resistant H. pylori by Pasala, Chiranjeevi, Chilamakuri, Chandra Sekhar Reddy, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Umamaheswari, Amineni

“…Gastric cancer risk and adverse ramifications by augmented multi-drug resistance (MDR) of Helicobacter pylori are alarming serious health concern. Combating…”
Get full text

GW27-e0531 Single nucleotide polymorphism of Methylenetetrahydrofolate reductase (MTHFR) gene and its relationship with serum Homocysteine levels in young Coronary artery disease patients of South-India by Kasala, Latheef, Durgaprasad, Rajasekhar, Velam, Vanajakshamma, PVGK, Sarma, Bitla, Aparna R, Chaudhury, Abhijit, Pakala, Vasudeva Chetty

“…[...]MTHFR 677 C >T polymorphism can be a possible genetic risk factor for premature coronary artery disease in South-Indian ethnic population…”
Get full text

Hierarchical-Clustering, Scaffold-Mining Exercises and Dynamics Simulations for Effectual Inhibitors Against Lipid-A Biosynthesis of Helicobacter pylori by Pasala, Chiranjeevi, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Amineni, Umamaheswari

“…Introduction Treatment failures of standard regimens and new strains egression are due to the augmented drug resistance conundrum. These confounding factors…”
Get full text

Assessment of serum microRNA-21 and miRNA-205 as diagnostic markers for stage I and II breast cancer in Indian population by Rama, Kanchi, Bitla, Aparna R, Hulikal, Narendra, Yootla, Mutheeswaraiah, Yadagiri, Lakshmi Amancharla, Asha, T, Manickavasagam, M, Srinivasa Rao, Pvln

“…Current markers (carcinoembryonic antigen [CEA] and carbohydrate antigen 15-3 [CA15-3]) lack sensitivity in diagnosis of breast cancer. The aberrantly…”
Get full text