Search Results - "Bitla, Aparna"

In silico trials to design potent inhibitors against matrilysin (MMP-7) by Katari, Sudheer Kumar, Pasala, Chiranjeevi, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Umamaheswari, Amineni

“…The study deals with structure-based rational drug design against the chief zinc-rely endopeptidase called matrilysin (MMP-7) that is involved in inflammatory…”
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Oxidative stress in relation to obesity in breast cancer by Sateesh, R, Rao Bitla, Aparna, Budugu, Sandya, Mutheeswariah, Y, Narendra, H, Phaneedra, B, Lakshmi, A

“…PURPOSE: Breast carcinoma is one of the most common neoplasms in women and is a leading cause of cancer-related deaths worldwide. Obesity-induced chronic…”
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Epitope-driven common subunit vaccine design against H. pylori strains by Pasala, Chiranjeevi, Chilamakuri, Chandra Sekhar Reddy, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Amineni, Umamaheswari

“…The developing potent vaccine is a pre-emptive strategy to tackle drug abuses and maladies of multidrug-resistant Helicobacter pylori strains. Ongoing vaccine…”
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In silico probing exercises, bioactive-conformational and dynamic simulations strategies for designing and promoting selective therapeutics against Helicobacter pylori strains by Pasala, Chiranjeevi, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Amineni, Umamaheswari

“…A myriad of drug-resistant strains of Helicobacter pylori and adverse drug-reactions create a big-barrier in the treatment, thereby demanding novel…”
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Effect of Rosuvastatin on Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Prospective Interventional Study by Thej, M Keerthi, Bitla, Aparna R, Rao, PVLNSrinivasa, Sachan, Alok

“…Introduction: Diabetes Mellitus (DM) is an established risk factor for Cardiovascular Disease (CVD). Oxidative Stress (OS) and inflammation are linked to CVD…”
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Intercellular adhesion molecule-1 is a surrogate biomarker for subclinical atherosclerosis in Type 2 diabetes mellitus by Sasikala, Thallapaneni, M Manohar, Suchitra, Rr Bitla, Aparna, Sarala, S, Vaikkakara, Suresh

“…We aimed to investigate biomarkers of inflammation, oxidative stress as surrogate markers of subclinical atherosclerosis in patients with Type 2 diabetes…”
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A Study of Oxidative Stress, Inflammation, and Endothelial Dysfunction in Diabetic and Nondiabetic Chronic Kidney Disease Pre-Dialysis Patients by Koppara, Naveen Kumar, Medooru, Kusuma Kumari, Yadagiri, Lakshmi Amancharla, Vishnubotla, Siva Kumar, Rapur, Ram, Bitla, Aparna R

“…Oxidative stress, inflammation, and endothelial dysfunction represent a key triad for the development and progression of atherosclerosis. Due to chronic…”
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Correction to: Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus by Naresh, Sriram, Bitla, Aparna R., Rao, P. V. L. N. Srinivasa, Sachan, Alok, Amancharla, Yadagiri Lakshmi

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus by Naresh, Sriram, Bitla, Aparna R., Rao, P. V. L. N. Srinivasa, Sachan, Alok, Amancharla, Yadagiri Lakshmi

“…Purpose High-density lipoprotein (HDL) undergoes structural and functional modification in patients with type 2 diabetes mellitus (T2DM). There are limited…”
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Attenuation of Oxidative Stress, Interleukin-6, High-Sensitivity C-Reactive Protein, Plasminogen Activator Inhibitor-1, and Fibrinogen with Oral Vitamin D Supplementation in Patients with T2DM having Vitamin D Deficiency by Pasupuleti, Pullaiah, Suchitra, M.M., Bitla, Aparna R., Sachan, Alok

“…Abstract Objectives  Type 2 diabetes mellitus (T2DM) associated with oxidative stress and inflammation causes endothelial dysfunction, which promotes…”
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An in silico study: Novel targets for potential drug and vaccine design against drug resistant H. pylori by Pasala, Chiranjeevi, Chilamakuri, Chandra Sekhar Reddy, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Umamaheswari, Amineni

“…Gastric cancer risk and adverse ramifications by augmented multi-drug resistance (MDR) of Helicobacter pylori are alarming serious health concern. Combating…”
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GW27-e0531 Single nucleotide polymorphism of Methylenetetrahydrofolate reductase (MTHFR) gene and its relationship with serum Homocysteine levels in young Coronary artery disease patients of South-India by Kasala, Latheef, Durgaprasad, Rajasekhar, Velam, Vanajakshamma, PVGK, Sarma, Bitla, Aparna R, Chaudhury, Abhijit, Pakala, Vasudeva Chetty

“…[...]MTHFR 677 C >T polymorphism can be a possible genetic risk factor for premature coronary artery disease in South-Indian ethnic population…”
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Hierarchical-Clustering, Scaffold-Mining Exercises and Dynamics Simulations for Effectual Inhibitors Against Lipid-A Biosynthesis of Helicobacter pylori by Pasala, Chiranjeevi, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Bitla, Aparna R., Amineni, Umamaheswari

“…Introduction Treatment failures of standard regimens and new strains egression are due to the augmented drug resistance conundrum. These confounding factors…”
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Assessment of serum microRNA-21 and miRNA-205 as diagnostic markers for stage I and II breast cancer in Indian population by Rama, Kanchi, Bitla, Aparna R, Hulikal, Narendra, Yootla, Mutheeswaraiah, Yadagiri, Lakshmi Amancharla, Asha, T, Manickavasagam, M, Srinivasa Rao, Pvln

“…Current markers (carcinoembryonic antigen [CEA] and carbohydrate antigen 15-3 [CA15-3]) lack sensitivity in diagnosis of breast cancer. The aberrantly…”
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Evaluation of protein oxidation and its association with lipid peroxidation and thyrotropin levels in overt and subclinical hypothyroidism by Haribabu, A., Reddy, V. Seshadri, Pallavi, Ch, Bitla, Aparna R., Sachan, Alok, Pullaiah, P., Suresh, V., Rao, P. V. L. N. Srinivasa, Suchitra, M. M.

“…Both overt (OHT) and subclinical hypothyroid (SHT) disorders have been found to be associated with increased oxidative stress (OXS). Excess thyrotropin…”
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Evaluation of the effectiveness of critical result notification protocol of biochemistry laboratory at a tertiary care hospital by Thota, Silpa, Bitla, Aparna R.

“…Background Critical value reporting is an essential aspect of laboratory medicine, ensuring prompt communication of life-threatening results to clinicians for…”
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Plasma osteopontin levels in patients with acute kidney injury requiring dialysis: a study in a tertiary care institute in South India by Varalakshmi, Boreddy, Kiranmyai, V. S., Aparna, Bitla, Ram, Rapur, Rao, P. V. L. N. Srinivas, Kumar, Vishnubotla Siva

“…Purpose Osteopontin (OPN) is evolving as a novel biomarker of injury, overall survival and renal outcome in critically ill patients with acute kidney injury…”
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Association of single nucleotide polymorphisms of adiponectin and leptin genes with breast cancer by Geriki, Sarvari, Bitla, Aparna R., SrinivasaRao, P. V. L. N., Hulikal, Narendra, Yootla, Mutheeswaraiah, Sachan, Alok, Amancharla Yadagiri, Lakshmi, Asha, T., Manickavasagam, M., Kannan, T., Kumari, Aruna P.

“…Single nucleotide polymorphisms (SNPs) in adiponectin gene [rs1501299 (+276G/T) and rs266729 (−11377C/G)] and one SNP of leptin gene [rs7799039 (−2548G/A)] are…”
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Utility of saliva as a sample to assess renal function and estimated glomerular filtration rate by Yajamanam, Naresh, Bitla, Aparna R., Vinapamula, Kiranmayi S., Sivakumar, V., Rao, P. V. L. N. Srinivas

“…Diagnosis of renal diseases by assessing renal parameters in saliva. Biochemical investigations using serum form important component of monitoring patients…”
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Study of contrast-induced oxidative stress in nondiabetic patients undergoing coronary angiography by Vishnubhotla, Sivakumar, Rajasekhar, D., Vinapamula, Kiranmayi S., Bitla, Aparna R., Srinivasa Rao, P. V. L. N., Manda, Prasanth, Jeyaseelan, L.

“…Administration of iodinated contrast media is associated with serious compli- cations such as acute kidney injury (AKI). Oxidative stress is implicated as a…”
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