Search Results - "Bithia, R."

Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach by Udhaya Kumar, S, Thirumal Kumar, D, Bithia, R, Sankar, Srivarshini, Magesh, R, Sidenna, Mariem, George Priya Doss, C, Zayed, Hatem

“…Familial hypercholesterolemia (FH) is one of the major risk factor for the progression of atherosclerosis and coronary artery disease. This study focused on…”
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Mutational landscape of K-Ras substitutions at 12th position-a systematic molecular dynamics approach by S, Udhaya Kumar, R, Bithia, D, Thirumal Kumar, Doss, C. George Priya, Zayed, Hatem

“…K-Ras is a small GTPase and acts as a molecular switch by recruiting GEFs and GAPs, and alternates between the inert GDP-bound and the dynamic GTP-bound forms…”
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Unraveling the intricate physiological processes dysregulated in CHD-affected and Dan-Lou tablet-treated individuals by Datta, Ankur, George, Neethu, Koppolu, Tejaswini, Kumar. S, Udhaya, Bithia, R., Zayed, Hatem, Doss. C, George Priya

“…Coronary heart disease (CHD), a multifactorial cardiovascular condition, arises from the accumulation of atherosclerotic plaque in the coronary arteries,…”
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Computational screening and structural analysis of Gly201Arg and Gly201Asp missense mutations in human cyclin-dependent kinase 4 protein by Thirumal Kumar, D, Shaikh, Nishaat, Bithia, R, Karthick, V, George Priya Doss, C, Magesh, R

“…The regulatory proteins, cyclins, and cyclin-dependent kinases (CDKs) control the cell cycle progression. CDK4 gene mutations are associated with certain…”
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Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach by Udhaya Kumar, S, Kamaraj, Balu, Varghese, Rinku Polachirakkal, Preethi, V Anu, Bithia, R, George Priya Doss, C

“…An increase in the fast blood glucose (FBG) levels has been linked to an increased risk of developing a chronic condition, type 2 diabetes (T2D). The mutation…”
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Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome by Thirumal Kumar, D, Udhaya Kumar, S, Nishaat Laeeque, Ahmed Shaikh, Apurva Abhay, Shivalkar, Bithia, R, Magesh, R, Kumar, Maignana, Zayed, Hatem, George Priya Doss, C

“…Blau syndrome (BS), which affects the eyes, skin, and joints, is an autosomal dominant genetic inflammatory disorder. BS is caused by mutations in the NOD2…”
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