Search Results - "Bithi, Nazmin"

Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner by Bithi, Nazmin, Link, Christopher, Henderson, Yoko O., Kim, Suzie, Yang, Jie, Li, Ling, Wang, Rui, Willard, Belinda, Hine, Christopher

“…Hydrogen sulfide (H 2 S) is a cytoprotective redox-active metabolite that signals through protein persulfidation (R-SS n H). Despite the known importance of…”
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Late-life intermittent fasting decreases aging-related frailty and increases renal hydrogen sulfide production in a sexually dimorphic manner by Henderson, Yoko O., Bithi, Nazmin, Link, Christopher, Yang, Jie, Schugar, Rebecca, Llarena, Natalia, Brown, J. Mark, Hine, Christopher

“…Global average life expectancy continues to rise. As aging increases the likelihood of frailty, which encompasses metabolic, musculoskeletal, and cognitive…”
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A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting by Henderson, Yoko O., Bithi, Nazmin, Yang, Jie, Link, Christopher, Zhang, Aili, Baron, Benjamin, Maina, Eran, Hine, Christopher

“…The global obesity pandemic coupled with ever-growing life expectancies equates to hundreds of millions of individuals with potentially longer but not…”
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Method validation of an inductively coupled plasma mass spectrometry (ICP-MS) assay for the analysis of magnesium, copper and zinc in red blood cells by Bithi, Nazmin, Ricks, Daniel, Walker, Brandon S., Law, Christian, Johnson-Davis, Kamisha L.

“…•ICP-MS method validation for the quantification of copper, magnesium and zinc elements in RBCs.•Retrospective data was analyzed, and non-parametric reference…”
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Trends in co-fractionation mass spectrometry: A new gold-standard in global protein interaction network discovery by Goel, Raghuveera Kumar, Bithi, Nazmin, Emili, Andrew

“…Co-fractionation mass spectrometry (CF-MS) uses biochemical fractionation to isolate and characterize macromolecular complexes from cellular lysates without…”
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Abstract 9410: Cardiovascular Disease Associated Metabolites TMA and TMAO Bind to Cystathionine Gamma-Lyase and Repress Its Enzymatic Production of Hydrogen Sulfide by Sharew, Betemariam, Kim, Suzie, Enders, Jacob, Bithi, Nazmin, Hine, Christopher

“…While the causative factors of smoking and hypertension leading to cardiovascular disease (CVD) are well understood, those involved with diet-induced CVD are…”
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Iron Catalyzed Hydrogen Sulfide and Its Prevalence during Oxidative Events in Sickle Cell Disease by Yang, Jie, Bithi, Nazmin, Link, Christopher, Saunthararajah, Yogenthiran, Hine, Christopher

“…In sickle cell disease (SCD), red blood cell (RBC) oxidation-reduction (redox) status is a critical determinant of hemolysis and RBC adhesion/vaso-occlusive…”
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Method validation of an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) assay for the analysis of Magnesium, Copper and Zinc in RBC by Bithi, Nazmin, Ricks, Daniel, Zuromski, Lauren M, Kish-Trier, Erik, Johnson-Davis, Kamisha L

“…Abstract Background Laboratory measurements of trace elements such as magnesium (Mg), copper (Cu) and zinc (Zn) in red blood cells (RBCs) are used to assess…”
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Severe consequences of a high-lipid diet include hydrogen sulfide dysfunction and enhanced aggression in glioblastoma by Silver, Daniel J, Roversi, Gustavo A, Bithi, Nazmin, Wang, Sabrina Z, Troike, Katie M, Neumann, Chase Ka, Ahuja, Grace K, Reizes, Ofer, Brown, J Mark, Hine, Christopher, Lathia, Justin D

“…Glioblastoma (GBM) remains among the deadliest of human malignancies, and the emergence of the cancer stem cell (CSC) phenotype represents a major challenge to…”
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Does Labetalol Trigger False Positive Drug Testing Results? by Bithi, Nazmin, Merrigan, Stephen D., McMillin, Gwendolyn A.

“…Labetalol, an α- and β-adrenergic antagonist used to treat hypertension in pregnancy has been blamed for causing false-positive amphetamine and methamphetamine…”
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Does Labetalol Trigger False Positive Drug Testing Results? by Bithi, Nazmin, Merrigan, Stephen D., McMillin, Gwendolyn A.

“…Labetalol, an α- and β-adrenergic antagonist used to treat hypertension in pregnancy has been blamed for causing false-positive amphetamine and methamphetamine…”
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Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex by Jonsson, William O, Margolies, Nicholas S, Mirek, Emily T, Zhang, Qian, Linden, Melissa A, Hill, Cristal M, Link, Christopher, Bithi, Nazmin, Zalma, Brian, Levy, Jordan L, Pettit, Ashley P, Miller, Joshua W, Hine, Christopher, Morrison, Christopher D, Gettys, Thomas W, Miller, Benjamin F, Hamilton, Karyn L, Wek, Ronald C, Anthony, Tracy G

“…Dietary sulfur amino acid restriction (SAAR) improves body composition and metabolic health across several model organisms in part through induction of the…”
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STEM-11. HYDROGEN SULFIDE FUNCTIONS AS A TUMOR SUPPRESSION IN GLIOBLASTOMA by Silver, Daniel J, Roversi, Gustavo, Bithi, Nazmin, Wang, Sabrina, Troike, Katie M, Neumann, Chase K, Ahuja, Grace, Reizes, Ofer, Brown, J Mark, Hine, Christopher, Lathia, Justin

“…Abstract Glioblastoma (GBM) cancer stem cells (CSCs) respond to a variety of stimuli within their immediate surroundings. However, little is known about the…”
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STEM-03. CONSUMPTION OF A HIGH-FAT DIET INHIBITS THE TUMOR SUPPRESSIVE ACTIVITY OF HYDROGEN SULFIDE, DRIVING CANCER STEM CELL ENRICHMENT AND DISEASE AGGRESSION IN GLIOBLASTOMA by Silver, Daniel, Roversi, Gustavo, Bithi, Nazmin, Troike, Katie, Neumann, Chase, Mark Brown, J, Hine, Christopher, Lathia, Justin

“…Abstract Glioblastoma (GBM) remains among the deadliest of human malignancies. Effective disease management is lacking due in part to the emergence of the…”
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Late-Onset Intermittent Fasting Decreases Aging-Related Frailty by Henderson, Yoko, Bithi, Nazmin, Link, Christopher, Yang, Jie, Hine, Christopher

“…Abstract Global average life expectancy continues to rise. As aging increases likelihoods of exhibiting geriatric syndromes (a.k.a. frailty), there is a need…”
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TAMI-12. CANCER STEM CELL ENRICHMENT AND METABOLIC SUBSTRATE ADAPTABILITY ARE DRIVEN BY HYDROGEN SULFIDE SUPPRESSION IN GLIOBLASTOMA by Silver, Daniel, Roversi, Gustavo, Bithi, Nazmin, Neumann, Chase K, Troike, Katie, Ahuja, Grace, Reizes, Ofer, Brown, J Mark, Hine, Christopher, Lathia, Justin

“…Abstract Glioblastoma (GBM) remains among the deadliest of human malignancies. The emergence of the cancer stem cell (CSC) phenotype represents a major…”
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Tissue Specific Protein Sulfhydration Profiling Under Dietary Restriction, Aging, and Neurooncological Disease by Bithi, Nazmin K

“…Aging and aging associated disorders like cardiovascular disease, glioblastoma multiform (GBM), neurodegeneration, and diabetes currently and increasingly…”
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ETMM-01. CANCER STEM CELL ENRICHMENT AND METABOLIC SUBSTRATE ADAPTABILITY ARE DRIVEN BY HYDROGEN SULFIDE SUPPRESSION IN GLIOBLASTOMA by Silver, Daniel J, Roversi, Gustavo A, Bithi, Nazmin, Neumann, Chase K A, Troike, Katie M, Ahuja, Grace K, Reizes, Ofer, Brown, J Mark, Hine, Christopher, Lathia, Justin D

“…Abstract Glioblastoma (GBM) remains among the deadliest of human malignancies. The emergence of the cancer stem cell (CSC) phenotype represents a major…”
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