Search Results - "Bitar, Khalil M"
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1
Aliskiren, exendin-4, and insulin: their impact on endothelin receptor subtype(s) regulation/binding in type 1 diabetic rat hearts
Published in Canadian journal of physiology and pharmacology (01-10-2013)“…This study focuses on the impact of aliskiren and (or) glucagon-like peptide-1 analogue on the binding affinity/regulation of endothelin-1 (ET-1) to its…”
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2
Kinetics of lipopolysaccharide clearance by Kupffer and parenchyma cells in perfused rat liver
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-08-2001)“…We studied the kinetics of [ 3H]lipopolysaccharide ([ 3H]LPS) (endotoxin) binding to Kupffer cells and hepatocytes at the level of the microtubular system…”
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3
Role of glucagon-like peptide-1 and its agonists on early prevention of cardiac remodeling in type 1 diabetic rat hearts
Published in General physiology and biophysics (01-03-2011)“…Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from intestinal L cells upon nutrients ingestion, and is currently used for treating diabetes…”
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4
Role of glucagon-like peptide-1 analogues on insulin receptor regulation in diabetic rat hearts
Published in Canadian journal of physiology and pharmacology (01-01-2010)“…This study focused on the regulation and affinity modulation of the insulin receptor of coronary endothelium and cardiomyocytes in nondiabetic and STZ-induced…”
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5
Effect of type-1 diabetes mellitus on the regulation of insulin and endothelin-1 receptors in rat hearts
Published in Canadian journal of physiology and pharmacology (01-02-2007)“…This project assesses the treatment role with insulin and (or) angiotensin II receptor subtype-1 (AT1-R) blocker (ARB) on insulin receptor and endothelin-1…”
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6
Effect of insulin and angiotensin II receptor subtype-1 antagonist on myocardial remodelling in rats with insulin-dependent diabetes mellitus
Published in Journal of hypertension (01-02-2005)“…To assess the role of insulin or an angiotensin II receptor antagonist (losartan), or both, in preventing cardiomyocyte damage in rats suffering from…”
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7
Cross-talk related to insulin and angiotensin II binding on myocardial remodelling in diabetic rat hearts
Published in Journal of the renin-angiotensin-aldosterone system (01-06-2007)“…This study focused on the regulation and affinity modulation of angiotensin II (Ang II) binding to its receptor subtypes (AT1- and AT2-receptor) in the…”
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8
Endothelin-1 receptor subtypes expression and binding in a perfused rat model of myocardial infarction
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (2003)“…Endothelin-1 (ET-1) pathophysiologic actions are mediated via binding with two receptor subtypes, ET A and ET B. Release of ET-1 from endocardial endothelial…”
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9
Endothelium and myocyte cellular insulin receptor alterations in a rat model of myocardial infarction
Published in Canadian journal of physiology and pharmacology (01-03-2003)“…Ischemic heart disease is considered to be one of the leading causes of death in adults. While extensive research on mechanisms contributing to the…”
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10
Characterization of insulin-resistance: role of receptor alteration in insulin-dependent diabetes mellitus, essential hypertension and cardiac hypertrophy
Published in European journal of pharmaceutical sciences (01-10-2000)“…Insulin-resistance is associated with a number of disease states such as diabetes, syndrome X, and hypertension. These situations may be coupled to…”
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11
Effect of systemic insulin and angiotensin II receptor subtype-1 antagonist on endothelin-1 receptor subtype(s) regulation and binding in diabetic rat heart
Published in Endothelium (New York, N.Y.) (01-09-2005)“…This study reports on the regulation and remodeling role of endothelin-1 (ET-1) and its receptor subtypes, ET(A)-Rs/ET(B)-Rs, at the coronary endothelium (CE)…”
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12
Angiotensin II binding and extracellular matrix remodelling in a rat model of myocardial infarction
Published in Journal of the renin-angiotensin-aldosterone system (01-12-2000)“…Clinical evidence points to a role for angiotensin II (Ang II) in the post-infarction remodelling of cardiac hypertrophy. The present study was designed to…”
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13
Assessment of Glucagon-Like Peptide-1 Analogue and Renin Inhibitor on the Binding and Regulation of GLP-1 Receptor in Type 1 Diabetic Rat Hearts
Published in Experimental diabetes research (01-01-2011)“…This study focuses on the effects of long-term renin-angiotensin system suppression and/or incretin mimetic therapies on the regulation and binding affinity of…”
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14
Binding and distribution of three prototype calcium channel blockers in perfused rat liver
Published in Molecular and cellular biochemistry (01-04-1997)“…This work represents a study of the binding and distribution of three different calcium channel blockers in the Sprague-Dawley rat liver, using an in situ…”
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15
Angiotensin II receptor subtypes regulation and affinity changes in treated IDDM rat hearts
Published in The FASEB journal (01-03-2006)“…Study focused on regulation and affinity of angiotensin II to its AT1‐Rs/AT2‐Rs at coronary endothelium (CE) and cardiomyocyte (CM) in normal and STZ‐induced…”
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16
Search for a parity-flavor-breaking phase in QCD with two flavors of Wilson fermions for β >~ 5.0
Published in Physical review. D, Particles and fields (01-09-1997)Get full text
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17
A new method to measure the chiral condensate in lattice QCD using Wilson fermions
Published in Physics letters. B (29-01-1998)“…Parity and flavor symmetry is not broken in QCD. Using this fact, we propose a new method to measure the chiral condensate in lattice QCD using Wilson fermions…”
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18
Study of the Nambu-Jona-Lasinio model on the lattice
Published in Physical review. D, Particles and fields (01-09-1994)“…We present our full analysis of the two flavor Nambu--Jona-Lasinio model with SU(2)[times]SU(2) chiral symmetry on the four-dimensional hypercubic lattice with…”
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19
Flavor—parity breaking in the NJL model with Wilson fermions
Published in Nuclear physics. Section B, Proceedings supplement (01-04-1995)“…The Nambu—Jona-Lasinio model is chirally symmetric. Addition of a Wilson term explicitly breaks this symmetry and leaves the model with a remaining…”
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20
Angiotensin II delivery and binding at the microvascular endothelium and cardiac myocyte surfaces in perfused rat hearts
Published in Journal of pharmaceutical sciences (01-11-1998)“…Peptide delivery toward its targets in an intact organ is equally as important as its routing from the systemic circulation to cell surface receptor sites. A…”
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