Search Results - "Biswas, Nidhan K."

The GenomeAsia 100K Project enables genetic discoveries across Asia by Wall, Jeffrey D, Stawiski, Eric W, Ratan, Aakrosh, Kim, Hie Lim, Kim, Changhoon, Gupta, Ravi, Suryamohan, Kushal

“…The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity of individuals in genomic datasets and led to reduced…”
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Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups by Maitra, Arindam, Biswas, Nidhan K., Amin, Kishore, Kowtal, Pradnya, Kumar, Shantanu, Das, Subrata, Sarin, Rajiv, Majumder, Partha P., Bagchi, I, Bairagya, B. B., Basu, A., Bhan, M. K., Chaturvedi, P., Das, D., D’Cruz, A., Dhar, R., Dutta, D., Ganguli, D., Gera, P., Gupta, T., Mahapatra, S., Mujawar, M. H. K., Mukherjee, S., Nair, S., Nikam, S., Nobre, M., Patil, A., Patra, S., Rama-Gowtham, M., Rao, T. S., Roy, B., Roychowdhury, B., Sarkar, D., Sarkar, S., Sarkar-Roy, N., Sutradhar, D.

“…Gingivo-buccal oral squamous cell carcinoma (OSCC-GB), an anatomical and clinical subtype of head and neck squamous cell carcinoma (HNSCC), is prevalent in…”
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SARS-CoV-2 mutation 614G creates an elastase cleavage site enhancing its spread in high AAT-deficient regions by Bhattacharyya, Chandrika, Das, Chitrarpita, Ghosh, Arnab, Singh, Animesh K., Mukherjee, Souvik, Majumder, Partha P., Basu, Analabha, Biswas, Nidhan K.

“…SARS-CoV-2 was first reported from China. Within three months, it evolved to 10 additional subtypes. Two evolved subtypes (A2 and A2a) carry a non-synonymous…”
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Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression by Singh, Richa, Das, Shreya, Datta, Sila, Mazumdar, Anjana, Biswas, Nidhan K, Maitra, Arindam, Majumder, Partha P, Ghose, Sandip, Roy, Bidyut, Galli, Alvaro

“…It is hypothesized that same driver gene mutations should be present in both oral leukoplakia and cancer tissues. So, we attempted to find out mutations at one…”
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Computational prediction of the molecular mechanism of statin group of drugs against SARS-CoV-2 pathogenesis by Ghosh, Dipanjan, Ghosh Dastidar, Debabrata, Roy, Kamalesh, Ghosh, Arnab, Mukhopadhyay, Debanjan, Sikdar, Nilabja, Biswas, Nidhan K., Chakrabarti, Gopal, Das, Amlan

“…Recently published clinical data from COVID-19 patients indicated that statin therapy is associated with a better clinical outcome and a significant reduction…”
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Multi-regional genomic and transcriptomic characterization of a melanoma-associated oral cavity cancer provide evidence for CASP8 alteration-mediated field cancerization by Chakravarty, Shouvik, Ghosh, Arnab, Das, Chitrarpita, Das, Subrata, Patra, Subrata, Maitra, Arindam, Ghose, Sandip, Biswas, Nidhan K

“…Precancerous and malignant tumours arise within the oral cavity from a predisposed "field" of epithelial cells upon exposure to carcinogenic stimulus. This…”
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Uracil as a biomarker for spatial pyrimidine metabolism in the development of gingivobuccal oral squamous cell carcinoma by Shaikh, Soni, Basu, Sangramjit, Bag, Swarnendu, Chatterjee, Ankita, Datta, Sourav, Banerjee, Devmalya, Manikantan, Kapila, Arun, Indu, Arun, Pattatheyil, Biswas, Nidhan K., Maitra, Arindam, Mishra, Deepak Kumar, Majumder, Partha P., Dhar, Harsh, Mukherjee, Geetashree

“…No biomarker has yet been identified that allows accurate diagnosis and prognosis of oral cancers. In this study, we investigated the presence of key…”
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MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2 by Sinha, Abarna, Ghosh, Abhisikta, Ghosh, Arnab, Mathai, Sonia, Bhaumik, Jaydip, Mukhopadhyay, Asima, Maitra, Arindam, Biswas, Nidhan K, Sengupta, Sharmila

“…MAL (T-lymphocyte maturation-associated protein) is highly downregulated in most cancers, including cervical cancer (CaCx), attributable to promoter…”
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Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival by Biswas, Nidhan K., Das, Subrata, Maitra, Arindam, Sarin, Rajiv, Majumder, Partha P.

“…The arachidonic acid metabolism (AAM) pathway promotes tumour progression. Chemical inhibitors of AAM pathway prolong post-treatment survival of cancer…”
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Application of Random Forest and data integration identifies three dysregulated genes and enrichment of Central Carbon Metabolism pathway in Oral Cancer by Mukhopadhyay, Srija, Ghosh, Sahana, Das, Debodipta, Arun, P, Roy, Bidyut, Biswas, Nidhan K, Maitra, Arindam, Majumder, Partha P

“…Studies of epigenomic alterations associated with diseases primarily focus on methylation profiles of promoter regions of genes, but not of other genomic…”
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Biological and clinical relevance of correlated expression levels of coding and long noncoding RNAs in HPV16 positive cervical cancers by Ghosh, Abhisikta, Sinha, Abarna, Ghosh, Arnab, Roy, Somrita, Mallick, Sumana, Kumar, Vinoth, Mathai, Sonia, Bhaumik, Jaydip, Mukhopadhyay, Asima, Sen, Saugata, Chandra, Aditi, Maitra, Arindam, Biswas, Nidhan K, Majumder, Partha P, Sengupta, Sharmila

“…Human papillomavirus (HPV) drives cervical cancer (CaCx) pathogenesis and viral oncoproteins jeopardize global gene expression in such cancers. In this study,…”
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A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients by Saha, Gourab, Singh, Richa, Mandal, Argha, Das, Subrata, Chattopadhyay, Esita, Panja, Prasun, Roy, Paromita, DeSarkar, Navonil, Gulati, Sumit, Ghatak, Supriyo, Ghosh, Shibajyoti, Banerjee, Sudeep, Roy, Bidyut, Ghosh, Saurabh, Chaudhuri, Dipankar, Arora, Neeraj, Biswas, Nidhan K, Sikdar, Nilabja

“…Pancreatic Ductal Adenocarcinoma (PDAC) is a cancer of the exocrine pancreas and 5-year survival rates remain constant at 7%. Along with PDAC, Periampullary…”
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Analysis of the whole transcriptome from gingivo-buccal squamous cell carcinoma reveals deregulated immune landscape and suggests targets for immunotherapy by Singh, Richa, De Sarkar, Navonil, Sarkar, Sumanta, Roy, Roshni, Chattopadhyay, Esita, Ray, Anindita, Biswas, Nidhan K, Maitra, Arindam, Roy, Bidyut

“…Gingivo-buccal squamous cell carcinoma (GBSCC) is one of the most common oral cavity cancers in India with less than 50% patients surviving past 5 years. Here,…”
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Upper respiratory tract microbiome profiles in SARS-CoV-2 Delta and Omicron infected patients exhibit variant specific patterns and robust prediction of disease groups by Nath, Shankha, Sarkar, Mousumi, Maddheshiya, Ankita, De, Debjit, Paul, Shouvik, Dey, Souradeep, Pal, Kuhu, Roy, Suman Kr, Ghosh, Ayan, Sengupta, Sharmila, Paine, Suman Kalyan, Biswas, Nidhan K, Basu, Analabha, Mukherjee, Souvik

“…The role of the upper respiratory tract (URT) microbiome in predicting lung health has been documented in several studies. The dysbiosis in COVID patients has…”
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Hedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clusters by Chandra, Vikas, Das, Tapojyoti, Gulati, Puneet, Biswas, Nidhan K, Rote, Sarang, Chatterjee, Uttara, Ghosh, Samarendra N, Deb, Sumit, Saha, Suniti K, Chowdhury, Anup K, Ghosh, Subhashish, Rudin, Charles M, Mukherjee, Ankur, Basu, Analabha, Dhara, Surajit

“…Hedgehog (Hh) signaling pathway is a valid therapeutic target in a wide range of malignancies. We focus here on glioblastoma multiforme (GBM), a lethal…”
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Mapinsights: deep exploration of quality issues and error profiles in high-throughput sequence data by Das, Subrata, Biswas, Nidhan K, Basu, Analabha

“…Abstract High-throughput sequencing (HTS) has revolutionized science by enabling super-fast detection of genomic variants at base-pair resolution…”
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Contrasting Distribution of SARS-CoV-2 Lineages across Multiple Rounds of Pandemic Waves in West Bengal, the Gateway of East and North-East States of India by Singh, Animesh K., Laskar, Rezwanuzzaman, Banerjee, Anindita, Mondal, Rajiv Kumar, Gupta, Bishal, Deb, Sonia, Dutta, Shreelekha, Patra, Subrata, Ghosh, Trinath, Sarkar, Sumanta, Ghosh, Shekhar, Bhattacharya, Sabyasachi, Roy, Debojyoti, Chakraborty, Ankita, Chowdhury, Meghna, Mahaptra, Surajit, Paul, Antara, Mazumder, Anup, Chowdhury, Aparna, Chatterjee, Shiv Sekhar, Sarkar, Arunabha, Ray, Raja, Pal, Kuhu, Jana, Angshuman, Barik, Goutam, Ganguly, Swagata, Chatterjee, Mitali, Majhi, Dipankar, Bandopadhyay, Bhaswati, Das, Saumitra, Maitra, Arindam, Biswas, Nidhan K.

“…The evolution of viral variants and their impact on viral transmission have been an area of considerable importance in this pandemic of severe acute…”
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Analysis of RNA sequences of 3636 SARS-CoV-2 collected from 55 countries reveals selective sweep of one virus type by Biswas, Nidhan, Majumder, Partha

“…Background & objectives: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus-2) is evolving with the progression of the pandemic. This study was aimed to…”
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Integrative analysis of genomic and transcriptomic data of normal, tumour, and co‐occurring leukoplakia tissue triads drawn from patients with gingivobuccal oral cancer identifies signatures of tumour initiation and progression by Ghosh, Arnab, Das, Chitrarpita, Ghose, Sandip, Maitra, Arindam, Roy, Bidyut, Majumder, Partha P., Biswas, Nidhan K.

“…A thickened, white patch — leukoplakia — in the oral cavity is usually benign, but sometimes (in ~9% of individuals) it progresses to malignant tumour. Because…”
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Unfurling the functional association between long intergenic noncoding RNAs (lincRNAs) and HPV16-related cervical cancer pathogenesis through weighted gene co-expression network analysis of differentially expressed lincRNAs and coding genes by Sinha, Abarna, Ghosh, Sahana, Ghosh, Abhisikta, Ghosh, Arnab, Mathai, Sonia, Bhaumik, Jaydip, Mukhopadhyay, Asima, Maitra, Arindam, Biswas, Nidhan K, Sengupta, Sharmila

“…Long intergenic noncoding RNAs (lincRNAs) do not overlap annotated coding genes and are located in intergenic regions, as opposed to antisense and…”
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