Search Results - "Biswal, Jayashree"
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Investigation of vital pathogenic target orotate phosphoribosyltransferases (OPRTase) from Thermus thermophilus HB8: Phylogenetic and molecular modeling approach
Published in Gene (01-06-2016)“…Biosynthesis pathways of pyrimidine and purine are shown to play an important role in regular cellular activities. The biosynthesis can occur either through de…”
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Small peptide inhibitor from the sequence of RUNX3 disrupts PAK1–RUNX3 interaction and abrogates its phosphorylation-dependent oncogenic function
Published in Oncogene (26-08-2021)“…P21 Activated Kinase 1 (PAK1) is an oncogenic serine/threonine kinase known to play a significant role in the regulation of cytoskeleton and cell morphology…”
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Gamma radiation induced synthesis of gold nanoparticles in aqueous polyvinyl pyrrolidone solution and its application for hydrogen peroxide estimation
Published in Radiation physics and chemistry (Oxford, England : 1993) (01-02-2012)“…Gold nanoparticles (Au nps) have been synthesized in aqueous solution of polyvinyl pyrrolidone (PVP) by gamma radiolysis from HAuCl 4·3H 2O precursor and in…”
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WaterMap and Molecular Dynamic Simulation-Guided Discovery of Potential PAK1 Inhibitors Using Repurposing Approaches
Published in ACS omega (19-10-2021)“…p21-Activated kinase 1 (PAK1) is positioned at the nexus of several oncogenic signaling pathways. Currently, there are no approved inhibitors for disabling the…”
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Evaluation of anti-wear properties of automobile lubricant with different additives using thin layer activation technique
Published in Journal of radioanalytical and nuclear chemistry (01-09-2020)“…Thin layer activation technique (TLA) has been used for measurement of wear rate of disc gears under lubricated condition. A synthetic base lubricant was…”
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Investigation of effect of an amine inhibitor on corrosion of carbon steel by using thin layer activation technique
Published in Journal of radioanalytical and nuclear chemistry (01-03-2020)“…In the present investigation, thin layer activation technique has been employed to study the effectiveness of an amine derivative compound, namely…”
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Short aspect ratio gold nanorods prepared using gamma radiation in the presence of cetyltrimethyl ammonium bromide (CTAB) as a directing agent
Published in Radiation physics and chemistry (Oxford, England : 1993) (01-04-2010)“…The synthesis of short aspect ratio gold nanorods using gamma radiation method by incorporating cetyltrimethyl ammonium bromide (CTAB) as a directing agent is…”
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Discovery of potent Camkk1 kinase inhibitors through e-pharmacophore and molecular screening approaches
Published in Journal of biomolecular structure & dynamics (13-04-2022)“…Diabetes is recognized as a major health problem and according to WHO estimates global prevalence of diabetes is expected to increase from 171 million in 2000…”
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Designing of potent anti-diabetic molecules by targeting SIK2 using computational approaches
Published in Molecular diversity (01-06-2023)“…Diabetes mellitus (DM) is one of the major health problems worldwide. WHO have estimated that 439 million people may have DM by the year 2030. Several classes…”
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Methods of preparation of microparticles for radioactive particle tracking experiments
Published in Applied radiation and isotopes (01-02-2021)“…Radioactive particle tracking (RPT) technique is a relatively newer technique for the characterization of flow of process materials (liquids, solids) in…”
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Preparation and characterization of cobalt-60 glass microspheres for radioactive particle tracking applications
Published in Applied radiation and isotopes (01-07-2022)“…The current work describes development and optimization of a process for preparation of cobalt-60 glass microspheres. These microspheres have potential for…”
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Evaluation of green inhibitors for corrosion control of bronze by using thin layer activation method
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01-08-2024)“…•Ascorbic acid, citric acid and oxalic acid have been evaluated for corrosion inhibition of bronze in acidic environment.•Thin layer activation technique is…”
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Investigation of translation initiation factor through protein-protein interactions and molecular dynamics approaches
Published in Molecular simulation (24-07-2023)“…A crucial biological process that involves both transcription and translation is protein synthesis. While, the translation mechanism endures protein synthesis…”
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Investigation of flow dynamics of molten glass in different solar glass production units using radiotracer method
Published in Applied radiation and isotopes (01-03-2023)“…A radiotracer investigation was previously carried out to characterize the flow of the molten glass and to identify the cause of poor quality of the glass…”
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Structural insights on binding mechanism of CAD complexes (CPSase, ATCase and DHOase)
Published in Journal of biomolecular structure & dynamics (13-06-2021)“…Pyrimidine biosynthetic pathway enzymes constitute an important target for the development of antitumor drugs. To understand the role of binding mechanisms…”
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Mixing efficacy and residence time distribution measurement in heavy water upgradation plant using radiotracer
Published in Nuclear engineering and technology (01-10-2024)Get full text
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Identification of Pak1 inhibitors using water thermodynamic analysis
Published in Journal of biomolecular structure & dynamics (02-01-2020)“…p21-activated kinases (Paks) play an integral component in various cellular diverse processes. The full activation of Pak is dependent upon several serine…”
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Evaluation of inhibition effect of poly vinyl pyrrolidone on corrosion of bronze in simulated acid rain using thin layer activation technique
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (15-09-2021)“…•Corrosion rate of bronze was measured in acidic solution using TLA method.•Poly vinyl pyrrolidone (PVP) was identified as a corrosion inhibitor.•The corrosion…”
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A microfluidic route for synthesis of scandium oxide microspheres, their characterization and neutron activation
Published in Applied radiation and isotopes (01-05-2024)“…Radioactive scandium-46 microspheres have applications in mapping flow in a chemical reactor through a technique known as radioactive particle tracking (RPT)…”
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Computational screening of potential inhibitors targeting MurF of Brugia malayi Wolbachia through multi-scale molecular docking, molecular dynamics and MM-GBSA analysis
Published in Molecular and biochemical parasitology (01-11-2021)“…•Lymphatic filariasis is a vector borne parasitic disease that infects human lymphatic system by nematode Brugia malayi.•Peptidoglycan biosynthesis pathway…”
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