Search Results - "Bissell, M.J"
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Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes
Published in Cold Spring Harbor Symposia on Quantitative Biology (2005)“…It is now widely accepted that elements of the cellular and tissue microenvironment are crucial regulators of cell behavior in culture and homeostasis in vivo,…”
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Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and in Vivo by Integrin Blocking Antibodies
Published in The Journal of cell biology (07-04-1997)“…In a recently developed human breast cancer model, treatment of tumor cells in a 3-dimensional culture with inhibitory β1-integrin antibody or its Fab…”
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370 The metastasis-promoting protein, S100A4, regulates mammary branching morphogenesis
Published in European journal of cancer supplements (2010)Get full text
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Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1987)“…When primary mouse mammary epithelial cells are cultured on plastic, they rapidly lose their ability to synthesize and secrete most milk proteins even in the…”
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The microstructure of laminin-111 compensates for dystroglycan loss in mammary epithelial cells in downstream expression of milk proteins
Published in Biomaterials (01-10-2019)“…Laminin-111 (Ln-1), an extracellular matrix (ECM) glycoprotein found in the basement membrane of mammary gland epithelia, is essential for lactation. In…”
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Modelling molecular mechanisms of breast cancer and invasion: lessons from the normal gland
Published in Biochemical Society transactions (01-02-2007)“…The interplay between genes and environment is complex, particularly when it comes to cancer. Studies on breast cancer cells have shown that environmental…”
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Matrix Metalloproteinase Stromelysin-1 Triggers a Cascade of Molecular Alterations That Leads to Stable Epithelial-to-Mesenchymal Conversion and a Premalignant Phenotype in Mammary Epithelial Cells
Published in The Journal of cell biology (29-12-1997)“…Matrix metalloproteinases (MMPs) regulate ductal morphogenesis, apoptosis, and neoplastic progression in mammary epithelial cells. To elucidate the direct…”
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Expression of Rous sarcoma virus-derived retroviral vectors in the avian blastoderm: potential as stable genetic markers
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1991)“…Retroviruses are valuable tools in studies of embryonic development, both as gene expression vectors and as cell lineage markers. In this study early chicken…”
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Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways
Published in Development (Cambridge) (01-01-1996)“…Postlactational involution of the mammary gland is characterized by two distinct physiological events: apoptosis of the secretory, epithelial cells undergoing…”
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Disruption of 3D Tissue Integrity Facilitates Adenovirus Infection by Deregulating the Coxsackievirus and Adenovirus Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (18-02-2003)“…The human coxsackievirus and adenovirus receptor (CAR) represents the primary cellular site of adenovirus attachment during infection. An understanding of the…”
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Tissue Phenotype Depends on Reciprocal Interactions between the Extracellular Matrix and the Structural Organization of the Nucleus
Published in Proceedings of the National Academy of Sciences - PNAS (08-12-1998)“…What determines the nuclear organization within a cell and whether this organization itself can impose cellular function within a tissue remains unknown. To…”
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Multi-faceted regulation of cell differentiation by extracellular matrix
Published in The FASEB journal (01-06-1993)“…Extracellular matrix (ECM) is an intricate network composed of an array of macromolecules, the importance of which is becoming increasingly apparent. The ECM…”
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Extracellular Matrix-Dependent Tissue-Specific Gene Expression in Mammary Epithelial Cells Requires both Physical and Biochemical Signal Transduction
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-1994)“…Extracellular matrix (ECM) profoundly influences the growth and differentiation of the mammary gland epithelium, both in culture and in vivo. Utilizing a…”
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Expression of Autoactivated Stromelysin-1 in Mammary Glands of Transgenic Mice Leads to a Reactive Stroma During Early Development
Published in The American journal of pathology (01-08-1998)“…Extracellular matrix and extracellular matrix-degrading matrix metalloproteinases play a key role in interactions between the epithelium and the mesenchyme…”
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Controlled microaspiration for high-pressure freezing: a new method for ultrastructural preservation of fragile and sparse tissues for TEM and electron tomography
Published in Journal of microscopy (Oxford) (01-05-2008)“…High-pressure freezing is the preferred method to prepare thick biological specimens for ultrastructural studies. However, the advantages obtained by this…”
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Simultaneous classification and relevant feature identification in high-dimensional spaces: application to molecular profiling data
Published in Signal processing (01-04-2003)“…Molecular profiling technologies monitor many thousands of transcripts, proteins, metabolites or other species concurrently in a biological sample of interest…”
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Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1
Published in Molecular and Cellular Biology (01-06-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis
Published in The Journal of cell biology (09-02-2005)Get full text
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Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis
Published in The Journal of cell biology (09-02-2005)Get full text
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