Search Results - "Bissell, M. J"
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Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis
Published in Integrative biology (Cambridge) (01-03-2017)“…Hyaluronan, CD44 and the Receptor for Hyaluronan-Mediated Motility (RHAMM, gene name HMMR) regulate stem cell differentiation including mesenchymal progenitor…”
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Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction
Published in Physiological reviews (01-01-1996)“…Reciprocal interactions between epithelium and mesenchyme mediate crucial aspects of embryonic development and direct the coordinated organogenesis, correct…”
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The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells
Published in Development (Cambridge) (01-08-2001)“…The mammary gland develops its adult form by a process referred to as branching morphogenesis. Many factors have been reported to affect this process. We have…”
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Disruption of 3D Tissue Integrity Facilitates Adenovirus Infection by Deregulating the Coxsackievirus and Adenovirus Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (18-02-2003)“…The human coxsackievirus and adenovirus receptor (CAR) represents the primary cellular site of adenovirus attachment during infection. An understanding of the…”
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Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones
Published in Endocrine-related cancer (01-06-2000)“…The changes in tissue architecture that accompany the development of breast cancer have been the focus of investigations aimed at developing new cancer…”
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Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and in Vivo by Integrin Blocking Antibodies
Published in The Journal of cell biology (07-04-1997)“…In a recently developed human breast cancer model, treatment of tumor cells in a 3-dimensional culture with inhibitory β1-integrin antibody or its Fab…”
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Phenotypic Reversion or Death of Cancer Cells by Altering Signaling Pathways in Three-Dimensional Contexts
Published in JNCI : Journal of the National Cancer Institute (02-10-2002)“…Background: We previously used a three-dimensional (3D) reconstituted basement membrane (rBM) assay to demonstrate that tumorigenic HMT-3522 T4–2 human breast…”
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Extracellular Matrix-Dependent Tissue-Specific Gene Expression in Mammary Epithelial Cells Requires both Physical and Biochemical Signal Transduction
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-1994)“…Extracellular matrix (ECM) profoundly influences the growth and differentiation of the mammary gland epithelium, both in culture and in vivo. Utilizing a…”
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Interaction with Basement Membrane Serves to Rapidly Distinguish Growth and Differentiation Pattern of Normal and Malignant Human Breast Epithelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1992)“…Normal human breast epithelial cells show a high degree of phenotypic plasticity in monolayer culture and express many traits that otherwise characterize tumor…”
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Control of Mammary Epithelial Differentiation: Basement Membrane Induces Tissue-Specific Gene Expression in the Absence of Cell-Cell Interaction and Morphological Polarity
Published in The Journal of cell biology (01-12-1991)“…Functional differentiation in mammary epithelia requires specific hormones and local environmental signals. The latter are provided both by extracellular…”
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Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix
Published in Science (American Association for the Advancement of Science) (10-02-1995)“…Apoptosis (programmed cell death) plays a major role in development and tissue regeneration. Basement membrane extracellular matrix (ECM), but not fibronectin…”
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Suppression of Apoptosis by Basement Membrane Requires Three-Dimensional Tissue Organization and Withdrawal from The Cell Cycle
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-1996)“…The basement membrane (BM) extracellular matrix induces differentiation and suppresses apoptosis in mammary epithelial cells, whereas cells lacking BM lose…”
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Tumor Plasticity Allows Vasculogenic Mimicry, a Novel Form of Angiogenic Switch: A Rose by Any Other Name?
Published in The American journal of pathology (01-09-1999)Get full text
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Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1
Published in Molecular and Cellular Biology (01-06-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The microstructure of laminin-111 compensates for dystroglycan loss in mammary epithelial cells in downstream expression of milk proteins
Published in Biomaterials (01-10-2019)“…Laminin-111 (Ln-1), an extracellular matrix (ECM) glycoprotein found in the basement membrane of mammary gland epithelia, is essential for lactation. In…”
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Multi-faceted regulation of cell differentiation by extracellular matrix
Published in The FASEB journal (01-06-1993)“…Extracellular matrix (ECM) is an intricate network composed of an array of macromolecules, the importance of which is becoming increasingly apparent. The ECM…”
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The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay
Published in Biochemistry and cell biology (01-01-1996)“…The extracellular matrix (ECM) is a dominant regulator of tissue development and homeostasis. "Designer microenvironments" in culture and in vivo model systems…”
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Functional culture models to study mechanisms governing apoptosis in normal and malignant mammary epithelial cells
Published in Journal of mammary gland biology and neoplasia (01-04-1999)“…Mammary tissue homeostasis depends upon dynamic interactions between the epithelial cells, their microenvironment (including the basement membrane and the…”
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Laminin Mediates Tissue-Specific Gene Expression in Mammary Epithelia
Published in The Journal of cell biology (01-05-1995)“…Tissue-specific gene expression in mammary epithelium is dependent on the extracellular matrix as well as hormones. There is good evidence that the basement…”
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Rescue of Mammary Epithelial Cell Apoptosis and Entactin Degradation by a Tissue Inhibitor of Metalloproteinases-1 Transgene
Published in The Journal of cell biology (01-12-1996)“…We have used transgenic mice overexpressing the human tissue inhibitor of metalloproteinases (TIMP)-1 gene under the control of the ubiquitous β-actin…”
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