Search Results - "Bisht, Shilpa"
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Tissue-location-specific transcription programs drive tumor dependencies in colon cancer
Published in Nature communications (15-02-2024)“…Cancers of the same tissue-type but in anatomically distinct locations exhibit different molecular dependencies for tumorigenesis. Proximal and distal colon…”
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Oxidative stress and male infertility
Published in Nature reviews. Urology (01-08-2017)“…Key Points Male infertility is a complex lifestyle-related disorder Oxidative stress has adverse effects on the structural and functional integrity of sperm…”
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Oxidative Stress Induced Damage to Paternal Genome and Impact of Meditation and Yoga - Can it Reduce Incidence of Childhood Cancer?
Published in Asian Pacific journal of cancer prevention : APJCP (2016)“…Background: Sperm DNA damage is underlying aetiology of poor implantation and pregnancy rates but also affects health of offspring and may also result in…”
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Tobacco Use Increases Oxidative DNA Damage in Sperm - Possible Etiology of Childhood Cancer
Published in Asian Pacific journal of cancer prevention : APJCP (2015)“…Background: Cigarette smoking and tobacco chewing are common modes of consuming tobacco all over the world. Parents need to be aware that germ cell integrity…”
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Epigenetic dynamics of aging and cancer development: current concepts from studies mapping aging and cancer epigenomes
Published in Current opinion in oncology (01-03-2024)“…This review emphasizes the role of epigenetic processes as incidental changes occurring during aging, which, in turn, promote the development of cancer. Aging…”
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Oxidative stress: Major executioner in disease pathology, role in sperm DNA damage and preventive strategies
Published in Frontiers in bioscience (Scholar edition) (01-06-2017)“…Oxidative stress (OS) has been implicated in a wide array of diseases such as neurodegenerative disorders, autoimmune diseases, complex lifestyle diseases and…”
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Abstract 230: Deep learning embedding-based segmentation for morphological analysis in organoids
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: The organoid model is a useful tool for modeling the cellular microenvironment of the organ from which they are derived. Organoids…”
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Yoga: Impact on sperm genome and epigenome - clinical consequences
Published in Annals of Neurosciences (01-04-2019)Get full text
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Identification of novel genes by targeted exome sequencing in Retinoblastoma
Published in Ophthalmic genetics (01-12-2022)“…Retinoblastoma (RB) is initiated by mutation in both alleles of gene. However, few cases may occur even in the absence of mutation suggesting the role of genes…”
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Impact of yoga based lifestyle intervention on psychological stress and quality of life in the parents of children with retinoblastoma
Published in Annals of Neurosciences (01-04-2019)“…Childhood cancers are associated with a psychological burden to the parents and hence, decline their mental and physical health and overall quality of life…”
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Retinoblastoma Genetics
Published in Advances in ophthalmology and optometry (01-08-2020)Get full text
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Sperm methylome alterations following yoga‐based lifestyle intervention in patients of primary male infertility: A pilot study
Published in Andrologia (01-05-2020)“…A majority of the cases of primary male infertility are idiopathic with the underlying molecular mechanisms contributing to the pathophysiology as yet unknown…”
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Oxidative Stress and Polymorphism in MTHFR SNPs (677 and 1298) in Paternal Sperm DNA is Associated with an Increased Risk of Retinoblastoma in Their Children: A Case-Control Study
Published in Journal of pediatric genetics (Birmingham, Ala.) (01-09-2018)“…Sperm DNA is considered as the most vulnerable to oxidative stress-induced damage that also impairs global sperm DNA methylation leading to sperm-associated…”
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Protamines and their role in pathogenesis of male infertility
Published in Translational cancer research (01-06-2016)Get full text
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Tobacco Use Increases Oxidative DNA Damage in Sperm - Possible Etiology of Childhood Cancer
Published in Asian Pacific journal of cancer prevention : APJCP (04-11-2015)Get full text
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Sperm DNA damage in non-familial sporadic heritable retinoblastoma (NFSHRb)
Published in Clinical epidemiology and global health (2015)“…Loss of sperm DNA integrity hampers accurate transmission of genetic information to offspring, which may lead to childhood morbidity or even cancer. Sperm DNA…”
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Identification of novel genes by targeted exome sequencing in Retinoblastoma
Published in Ophthalmic Genetics: Special Issue: Festschrift: Dedicated to the life and work of A. Linn Murphree, MD (02-11-2022)“…Retinoblastoma (RB) is initiated by mutation in both alleles of RB1 gene. However, few cases may occur even in the absence of RB1 mutation suggesting the role…”
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Tobacco Use Increases Oxidative DNA Damage in Sperm - Possible Etiology of Childhood Cancer
Published in Asian Pacific journal of cancer prevention : APJCP (2015)“…Cigarette smoking and tobacco chewing are common modes of consuming tobacco all over the world. Parents need to be aware that germ cell integrity is vital for…”
Get more information
Journal Article