Search Results - "Bisgaard, Line S"
-
1
Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression – implications for atherosclerosis research
Published in Scientific reports (13-10-2016)“…Macrophages are heterogeneous and can polarize into specific subsets, e.g. pro-inflammatory M1-like and re-modelling M2-like macrophages. To determine if…”
Get full text
Journal Article -
2
The apoM/S1P Complex—A Mediator in Kidney Biology and Disease?
Published in Frontiers in medicine (14-10-2021)“…Kidney disease affects more than 10% of the population, can be both acute and chronic, and is linked to other diseases such as cardiovascular disease,…”
Get full text
Journal Article -
3
Liraglutide Reduces Both Atherosclerosis and Kidney Inflammation in Moderately Uremic LDLr-/- Mice
Published in PloS one (16-12-2016)“…Chronic kidney disease (CKD) leads to uremia. CKD is characterized by a gradual increase in kidney fibrosis and loss of kidney function, which is associated…”
Get full text
Journal Article -
4
Kidney derived apolipoprotein M and its role in acute kidney injury
Published in Frontiers in pharmacology (2024)“…Apolipoprotein M (apoM) is mainly expressed in liver and in proximal tubular epithelial cells in the kidney. In plasma, apoM associates with HDL particles via…”
Get full text
Journal Article -
5
Uremia does not affect neointima formation in mice
Published in Scientific reports (26-07-2017)“…Atherosclerotic cardiovascular disease is a major complication of chronic kidney disease (CKD). CKD leads to uremia, which modulates the phenotype of aortic…”
Get full text
Journal Article -
6
Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation and kidney biology
Published in Current opinion in lipidology (01-06-2019)“…In 2011, the crystal structure of apolipoprotein M (apoM) and its capacity to bind sphingosine-1-phosphate (S1P) was characterized. Since then, a variety of…”
Get full text
Journal Article -
7
The metabolic signature of cardiovascular disease and arterial calcification in patients with chronic kidney disease
Published in Atherosclerosis (01-06-2022)“…The relationship between chronic kidney disease (CKD) and cardiovascular events is well-established. Clinically recognised risk factors of cardiovascular…”
Get full text
Journal Article -
8
Uremia increases QRS duration after β‐adrenergic stimulation in mice
Published in Physiological reports (01-07-2018)“…Chronic kidney disease (CKD) and uremia increase the risk of heart disease and sudden cardiac death. Coronary artery disease can only partly account for this…”
Get full text
Journal Article -
9
Effect of atrial natriuretic peptide on lipolysis in the mouse heart
Published in Cardiovascular endocrinology (01-09-2014)“…Overweight is associated with triglyceride accumulation in cardiomyocytes, which can cause cardiac dysfunction. It is also associated with reduced synthesis…”
Get full text
Journal Article