Search Results - "Biserni, Andrea"
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Estrogen receptor β and the progression of prostate cancer: role of 5α-androstane-3β,17β-diol
Published in Endocrine-related cancer (01-09-2010)“…Prostate cancer (PC) develops in response to an abnormal activation of androgen receptor induced by circulating androgens and, in its initial stages, is…”
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In vivo imaging reveals selective peroxisome proliferator activated receptor modulator activity of the synthetic ligand 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886)
Published in Molecular pharmacology (01-05-2008)“…We report here the finding of a new pharmacological activity of a well known antagonist of peroxisome proliferator-activated receptors (PPARs). PPARs belong to…”
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3
The Conundrum of Estrogen Receptor Oscillatory Activity in the Search for an Appropriate Hormone Replacement Therapy
Published in Endocrinology (Philadelphia) (01-06-2011)“…Estrogen receptor transcriptional activity oscillates in time with a period and amplitude that are tissue-specific and only partially modulated by circulating…”
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4
A Novel Peroxisome Proliferator-Activated Receptor Responsive Element-Luciferase Reporter Mouse Reveals Gender Specificity of Peroxisome Proliferator-Activated Receptor Activity in Liver
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2007)“…There is a growing interest in peroxisome proliferator-activated receptors (PPARs) as major players in the regulation of lipid and carbohydrate metabolism…”
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An Innovative Method to Classify SERMs Based on the Dynamics of Estrogen Receptor Transcriptional Activity in Living Animals
Published in Molecular endocrinology (Baltimore, Md.) (01-04-2010)“…Using a mouse model engineered to measure estrogen receptor (ER) transcriptional activity in living organisms, we investigated the effect of long-term (21 d)…”
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Abstract 4319: A novel tool to study apoptosis in living mice
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…INTRODUCTION. The limitations of cellular models and xenograft for the identification of anti-neoplastic drugs are well known. The purpose of our study is to…”
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Techniques: Reporter mice – a new way to look at drug action
Published in Trends in pharmacological sciences (Regular ed.) (01-06-2004)“…During the past decade remarkable progress in molecular genetics and the possibility of manipulating cells so that the expression of genes can directly…”
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Cancer modeling: Modern imaging applications in the generation of novel animal model systems to study cancer progression and therapy
Published in The international journal of biochemistry & cell biology (01-01-2007)“…Cancer is the result of a series of genetic and epigenetic mutations that evolve over years even decades and lead to the transformed phenotype. Paradoxically,…”
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Profiling of drug action using reporter mice and molecular imaging
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2010)“…Reporter mice associated to molecular imaging represent a major asset for the study of the spatio-temporal effects of drugs in living animals. The field is…”
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10
Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol
Published in Endocrine-related cancer (01-09-2010)“…Prostate cancer (PC) develops in response to an abnormal activation of androgen receptor induced by circulating androgens and, in its initial stages, is…”
Get full text
Journal Article