Search Results - "Bisegna, R"
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Evaluation of widely used models for predicting BRCA1 and BRCA2 mutations
Published in Journal of medical genetics (01-04-2004)“…[...]all models except the Myriad Tables overestimated mutation probabilities in the highest risk group Overall, two of the Mendelian models (Brcapro and a…”
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Reducing breast cancer incidence in familial breast cancer: overlooking the present panorama
Published in Annals of oncology (01-01-2004)“…Familial breast cancer, whether associated or not with particular other breast cancer features (male, early onset, bilateral breast cancer), determines a wide…”
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Prognostic value of p53 molecular status in high-risk primary breast cancer
Published in Annals of oncology (01-05-2003)“…Background: Mutations in the p53 gene are the most common genetic alterations in human primary breast carcinoma and these mutations are often associated with…”
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Immunologic Mechanisms Mediate Benefits of Lutenizing Hormone-Releasing Hormone (LH-RH) in High Risk Premenopausal Breast Cancer Patients (HR-Pre-BC)
Published in Cancer research (Chicago, Ill.) (15-12-2009)“…Abstract Background: Systematic reviews have found that LH-RH agonists are effective in the treatment of premenopausal women with early breast cancer. In an…”
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Multicenter phase II study of sequential chemotherapy, radiotherapy, and immunotherapy in locally advanced pancreatic (Pa) and biliary tree (Bt) adenocarcinoma (ADK)
Published in Journal of clinical oncology (20-05-2009)“…Abstract only 3047 Background: The aim of this study was to evaluate the activity and toxicity of a multistep, sequential treatment including induction…”
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Total estrogen blockade (TEB) plus adjuvant chemotherapy in high-risk estrogen receptor-positive (ER+) premenopausal breast cancer: Long term results of an ovarian protection study
Published in Journal of clinical oncology (20-05-2008)“…Abstract only…”
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Immunotherapy in Patients with Less than Complete Response to Chemotherapy
Published in Anticancer research (01-02-2009)“…Background: Patients with metastatic solid tumors (MST) with less than a complete response to chemotherapy (L-CR), a depressed immune system and elevated serum…”
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Maintenance Immunotherapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Published in Journal of immunotherapy (1997) (01-05-2008)“…The purpose of this study was to determine the efficacy and safety of a maintenance immunotherapy regimen administered to patients with recurrent/metastatic…”
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Evidence of a founder mutation of BRCA1 in a highly homogeneous population from southern Italy with breast/ovarian cancer
Published in Human mutation (01-08-2001)“…Several genes have been involved in the pathogenesis of hereditary breast/ovarian cancer (BOC), but mutations in the BRCA1 gene are by far the most recurrent…”
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Different expressivity of BRCA1 and BRCA2: analysis of 179 Italian pedigrees with identified mutation
Published in Breast cancer research and treatment (01-09-2003)“…Mutations in BRCA1 and BRCA2 show different expressivity with respect to cancer risk, and allelic heterogeneity may be present in both genes. We collected 179…”
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Can analysis of the molecular status of the p53 gene contribute to improving the therapeutic strategy for breast carcinoma?
Published in Tumori (01-07-2003)“…The occurrence of mutations in the p53 tumor suppressor gene is a specific and recurring genetic event in solid tumors. P53 plays a pivotal role in multiple…”
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