Search Results - "Bisceglie, Franco"
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Antiproliferative Activity and DNA Interaction Studies of a Series of N4,N4-Dimethylated Thiosemicarbazone Derivatives
Published in Molecules (Basel, Switzerland) (20-03-2023)“…The exploitation of bioactive natural sources to obtain new anticancer agents with novel modes of action may represent an innovative and successful strategy in…”
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New Stable Gallium(III) and Indium(III) Complexes with Thiosemicarbazone Ligands: A Biological Evaluation
Published in Molecules (Basel, Switzerland) (19-01-2024)“…The aim of this work is to explore a new library of coordination compounds for medicinal applications. Gallium is known for its various applications in this…”
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3
Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study
Published in Scientific reports (29-06-2020)“…Thiosemicarbazones (TSC) and their metal complexes display diverse biological activities and are active against multiple pathological conditions ranging from…”
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Modulation of Transcription Profile Induced by Antiproliferative Thiosemicarbazone Metal Complexes in U937 Cancer Cells
Published in Pharmaceutics (24-04-2023)“…Since the discovery of cisplatin, the search for metal-based compounds with therapeutic potential has been a challenge for the scientific community. In this…”
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5
Light Triggers the Antiproliferative Activity of Naphthalimide-Conjugated (η6-arene)ruthenium(II) Complexes
Published in International journal of molecular sciences (10-07-2022)“…We report the synthesis and characterization of three half-sandwich Ru(II) arene complexes [(η6-arene)Ru(N,N′)L][PF6]2 containing arene = p-cymene, N,N′ =…”
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Transient Adaptation of Toxoplasma gondii to Exposure by Thiosemicarbazone Drugs That Target Ribosomal Proteins Is Associated with the Upregulated Expression of Tachyzoite Transmembrane Proteins and Transporters
Published in International journal of molecular sciences (21-08-2024)“…Thiosemicarbazones and their metal complexes have been studied for their biological activities against bacteria, cancer cells and protozoa. Short-term in vitro…”
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A New Photoactivatable Ruthenium(II) Complex with an Asymmetric Bis-Thiocarbohydrazone: Chemical and Biological Investigations
Published in Molecules (Basel, Switzerland) (10-02-2021)“…The synthesis, photoactivation and biological activity of a new piano-stool Ru(II) complex is herein reported. The peculiarity of this complex is that its…”
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8
Thiosemicarbazone nano-formulation for the control of Aspergillus flavus
Published in Environmental science and pollution research international (01-06-2020)“…Nanoparticles are widely studied for applications in medical science. In recent years, they have been developed for agronomical purposes to target microbial…”
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Double Gamers-Can Modified Natural Regulators of Higher Plants Act as Antagonists against Phytopathogens? The Case of Jasmonic Acid Derivatives
Published in International journal of molecular sciences (17-11-2020)“…As key players in biotic stress response of plants, jasmonic acid (JA) and its derivatives cover a specific and prominent role in pathogens-mediated signaling…”
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10
Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus , Using Yeast as a Model System
Published in Molecules (Basel, Switzerland) (16-08-2019)“…Amongst the various approaches to contain aflatoxin contamination of feed and food commodities, the use of inhibitors of fungal growth and/or toxin…”
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Phyto-Beneficial Traits of Rhizosphere Bacteria: In Vitro Exploration of Plant Growth Promoting and Phytopathogen Biocontrol Ability of Selected Strains Isolated from Harsh Environments
Published in Plants (Basel) (17-01-2022)“…Beneficial interactions between plants and some bacterial species have been long recognized, as they proved to exert various growth-promoting and…”
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The AFLATOX ® Project: Approaching the Development of New Generation, Natural-Based Compounds for the Containment of the Mycotoxigenic Phytopathogen Aspergillus flavus and Aflatoxin Contamination
Published in International journal of molecular sciences (26-04-2021)“…The control of the fungal contamination on crops is considered a priority by the sanitary authorities of an increasing number of countries, and this is also…”
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13
Effect of Thiosemicarbazone Derivatives and Fusarium culmorum (Wm.G. Sm.) Sacc. Infection of Winter Wheat Seedlings on Their Health Status and Soil Biological Activity
Published in Agronomy (Basel) (01-01-2022)“…Climate change has an impact on agricultural production, including the greater persistence of plant pathogens in the environment. Therefore, the question…”
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14
Synthesis, characterization and biological activity of Ni, Cu and Zn complexes of isatin hydrazones
Published in Journal of inorganic biochemistry (01-02-2004)“…Nickel, copper, and zinc complexes of isatin (H 2L 1) and N-methylisatin 3-picolinoyl hydrazone (HL 2), were synthesized and characterized by means of…”
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Structural and Magnetic Properties of Carboxylato-Bridged Manganese(II) Complexes Involving Tetradentate Ligands: Discrete Complex and 1D Polymers. Dependence of J on the Nature of the Carboxylato Bridge
Published in Inorganic chemistry (01-12-2003)“…The crystal structure of an inorganic linear polymer consisting of Mn(II) and an N-centered tripodal ligand N,N-bis(2-(6-methyl)pyridylmethyl)glycinate is…”
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A Biotechnological Approach for the Development of New Antifungal Compounds to Protect the Environment and the Human Health
Published in Journal of public health research (17-11-2015)“…Background In the Po Valley aflatoxins play a relevant role: the local food economy is heavily based on cereal cultivations for animal feed and human…”
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17
Effects of Artificial Aging on Polyurethane Resins Used in Geotechnical Works
Published in Journal of materials in civil engineering (01-05-2023)“…AbstractPolyurethane resins are often used in the geotechnical domain to fill fine fissures, small underground cavities, or soil pores to reduce soil…”
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Antibacterial activity of metal complexes based on cinnamaldehyde thiosemicarbazone analogues
Published in Journal of inorganic biochemistry (01-02-2020)“…The development of microbial antibiotic resistance has become one of the biggest threats to global health and the search for new molecules active against…”
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Synthesis, Solution Chemistry, X-ray Structure and Biological Activity of Novel Pyridoxal Thiosemicarbazone Derivatives
Published in Bulletin of the Chemical Society of Japan (2002)“…Novel ligands were obtained by condensation of pyridoxal with thiosemicarbazides substituted with alkyl and aryl moieties on the aminic and/or hydrazinic…”
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20
Bismuth complex of quinoline thiosemicarbazone restores carbapenem sensitivity in NDM-1-positive Klebsiella pneumoniae
Published in Journal of inorganic biochemistry (01-09-2022)“…Resistant bacteria represent an urgent worldwide threat. NDM-1-producing strains are rendering the last line antibiotics less effective. Six bismuth complexes…”
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