Search Results - "Biscaia, Isabela"
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Synthesis and Characterization of Ezetimibe Pharmaceutical Cocrystal: A Reaction Crystallization Method to Improve Physicochemical Properties and Hypolipemic Activity Evaluation
Published in Journal of the Brazilian Chemical Society (2024)“…Ezetimibe has significant lipid-lowering activity but presents low aqueous solubility. Co-crystallization techniques can be used to overcome this limitation…”
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Development of a First-Order Derivative UV Spectrophotometric Method for the Assay and Solubility Evaluation of Lamotrigine and Nicotinamide Cocrystals
Published in Journal of the Brazilian Chemical Society (01-12-2020)“…Pharmaceutical cocrystals are composed of a drug and a coformer and are currently gaining attention due to their possibility of improving drug solubility…”
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Solid-State Characterization and Compatibility Studies of Penciclovir, Lysine Hydrochloride, and Pharmaceutical Excipients
Published in Materials (27-09-2019)“…The physical and chemical characterization of the solid-state properties of drugs and excipients is fundamental for planning new formulations and developing…”
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Polymer selection to increase in vitro supersaturation generated by lamotrigine nicotinamide monohydrate cocrystal: An evaluation with predissolved and solid polymers
Published in Journal of drug delivery science and technology (01-07-2022)“…Cocrystals can improve drug dissolution by generating supersaturated drug delivery systems. However, supersaturation is a high-energetic state with a tendency…”
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Obtaining Cocrystals by Reaction Crystallization Method: Pharmaceutical Applications
Published in Pharmaceutics (17-06-2021)“…Cocrystals have gained attention in the pharmaceutical industry due to their ability to improve solubility, stability, in vitro dissolution rate, and…”
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Cocrystals Enhance Biopharmaceutical and Antimicrobial Properties of Norfloxacin
Published in Pharmaceutics (26-08-2023)“…A solvate cocrystal of the antimicrobial norfloxacin (NFX) was formed by using isonicotinamide (INA) as a coformer with the solvent evaporation technique. The…”
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