Search Results - "Bisaillon, Richard"

Genetic characterization of ABT-199 sensitivity in human AML by Bisaillon, Richard, Moison, Céline, Thiollier, Clarisse, Krosl, Jana, Bordeleau, Marie-Eve, Lehnertz, Bernhard, Lavallée, Vincent-Philippe, MacRae, Tara, Mayotte, Nadine, Labelle, Caroline, Boucher, Geneviève, Spinella, Jean-François, Boivin, Isabel, D’Angelo, Giovanni, Lavallée, Sylvie, Marinier, Anne, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy

“…Acute myeloid leukemias (AML) with mutations in the NPM1 gene (NPM1c+) represent a large AML subgroup with varying response to conventional treatment,…”
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Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells by Tomellini, Elisa, Fares, Iman, Lehnertz, Bernhard, Chagraoui, Jalila, Mayotte, Nadine, MacRae, Tara, Bordeleau, Marie-Ève, Corneau, Sophie, Bisaillon, Richard, Sauvageau, Guy

“…Transplantation of expanded hematopoietic stem cells (HSCs) and gene therapy based on HSC engineering have emerged as promising approaches for the treatment of…”
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Genetic Characterization of ABT-199 Sensitivity in Human AML by Bordeleau, Marie-Eve, Bisaillon, Richard, Thiollier, Clarisse, Krosl, Jana, Lehnertz, Bernhard, Lavallee, Vincent-Philippe, MacRae, Tara, Caroline, Labelle, Boucher, Geneviève, Boivin, Isabel, D'Angelo, Giovanni, Lavallée, Sylvie, Marinier, Anne, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy

“…Acute myeloid leukemias (AML) are aggressive blood cancers characterized by an overall survival of 27% at 5 years. The main challenge in AML treatment…”
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Targeted therapy in aml: looking beyond mutations with leucegene project by Sauvageau, Guy, Marinier, Anne, Lemieux, Sébastien, Thiollier, Clarisse, Simon, Laura, Bisaillon, Richard, Baccelli, Irene, Lavallée, Vincent, Hébert, Josée

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Identification of MEIS-PBX inhibitors as potential anti-leukemic agents using a high-throughput bret-based assay by Bisaillon, Richard, Schmidt, Eva, Guenier, Anne-Sophie, Sauvageau, Guy

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C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein by Bisaillon, Richard, Wilhelm, Brian T., Krosl, Jana, Sauvageau, Guy

“…The three-amino-acid loop extension (TALE) class homeodomain proteins MEIS1 and PKNOX1 (PREP1) share the ability to interact with PBX and HOX family members…”
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Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia by Krosl, Jana, Bordeleau, Marie-Eve, Moison, Céline, MacRae, Tara, Boivin, Isabel, Mayotte, Nadine, Gracias, Deanne, Baccelli, Irène, Lavallée, Vincent-Philippe, Bisaillon, Richard, Lehnertz, Bernhard, Mendoza-Sanchez, Rodrigo, Ruel, Réjean, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, Boucher, Geneviève, Noronha, Nandita, Pabst, Caroline, Tyers, Mike, Gendron, Patrick, Lemieux, Sébastien, Barabé, Frédéric, Marinier, Anne, Hébert, Josée, Sauvageau, Guy

“…Cholesterol homeostasis has been proposed as one mechanism contributing to chemoresistance in AML and hence, inclusion of statins in therapeutic regimens as…”
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Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation by Mamo, Aline, Krosl, Jana, Kroon, Evert, Bijl, Janet, Thompson, Alexander, Mayotte, Nadine, Girard, Simon, Bisaillon, Richard, Beslu, Nathalie, Featherstone, Mark, Sauvageau, Guy

“…The Hoxa9 and Meis1 genes represent important oncogenic collaborators activated in a significant proportion of human leukemias with genetic alterations in the…”
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