Search Results - "Bis, J."
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The Alzheimer's Disease Sequencing Project: Study design and sample selection
Published in Neurology. Genetics (01-10-2017)Get full text
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A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly
Published in Molecular psychiatry (01-12-2014)“…Amyloid beta (Aβ) peptides are the major components of senile plaques, one of the main pathological hallmarks of Alzheimer disease (AD). However, Aβ peptides'…”
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Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
Published in BMJ (19-02-2011)“…Objective To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease.Design…”
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PP025-SUN OXIDATIVE DNA DAMAGE IN ACUTE MYOCARDIAL INFARCTION
Published in Clinical nutrition (Edinburgh, Scotland) (01-09-2013)Get full text
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Relative effects of LDL-C on ischemic stroke and coronary disease: A Mendelian randomization study
Published in Neurology (12-03-2019)“…OBJECTIVETo examine the causal relevance of lifelong differences in low-density lipoprotein cholesterol (LDL-C) for ischemic stroke (IS) relative to that for…”
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The role of VEGF in the elderly diabetic patients undergoing endovascular therapy of advanced atherosclerotic aortic valve stenosis
Published in Atherosclerosis (01-08-2014)Get full text
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Lipoprotein-Associated Phospholipase A2 Mass Level Is Increased in Elderly Subjects with Type 2 Diabetes Mellitus
Published in Journal of diabetes research (2014)“…Objective. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is extensively expressed by advanced atherosclerotic lesions and may play a role in plaque…”
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Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility
Published in Molecular psychiatry (01-04-2014)“…Bipolar disorder (BD) is a polygenic disorder that shares substantial genetic risk factors with major depressive disorder (MDD). Genetic analyses have reported…”
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The role of VEGF in the diabetic patients undergoing endovascular therapy of symptomatic aortic valve stenosis
Published in Physiological research (01-01-2014)“…The aim of this study was to explore changes in plasma vascular endothelial growth factor (VEGF) in aged patients who undergone transcatheter aortic valve…”
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Genome‐wide association studies of cardiovascular risk factors: design, conduct and interpretation
Published in Journal of thrombosis and haemostasis (01-07-2009)“…Relying on known biology, candidate‐gene studies have been only modestly successful in identifying genetic variants associated with cardiovascular risk…”
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Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables
Published in Statistics in medicine (30-05-2010)“…Genetic markers can be used as instrumental variables, in an analogous way to randomization in a clinical trial, to estimate the causal relationship between a…”
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Variation in 24 hemostatic genes and associations with non‐fatal myocardial infarction and ischemic stroke
Published in Journal of thrombosis and haemostasis (01-01-2008)“…Background: Arterial thrombosis involves platelet aggregation and clot formation, yet little is known about the contribution of genetic variation in…”
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Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry
Published in The pharmacogenomics journal (01-06-2020)“…Hypertension (HTN) is a significant risk factor for cardiovascular morbidity and mortality. Metabolic abnormalities, including adverse cholesterol and…”
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Collaborative Pooled Analysis of Data on C-Reactive Protein Gene Variants and Coronary Disease: Judging Causality by Mendelian Randomisation
Published in European journal of epidemiology (2008)“…Many prospective studies have reported associations between circulating C-reactive protein (CRP) levels and risk of coronary heart disease (CHD), but causality…”
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Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus
Published in Molecular psychiatry (01-12-2015)“…We investigated the genetic overlap between Alzheimer’s disease (AD) and Parkinson’s disease (PD). Using summary statistics ( P -values) from large recent…”
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Failure of noninvasive prediction of pulmonary hypertension in patients with idiopathic pulmonary fibrosis
Published in Monaldi archives for chest disease (01-09-2011)“…Pulmonary hypertension (PH) in patients with advanced idiopathic pulmonary fibrosis (IPF) is a complication connected with unfavorable prognosis. Great efforts…”
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Time-course of tissue factor plasma level in patients with acute coronary syndrome
Published in Physiological research (01-01-2009)“…Enhanced expression of tissue factor (TF) may result in thrombosis contributing to acute clinical consequences of coronary artery disease. Several studies…”
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Plasma tissue factor in coronary artery disease: further step to the understanding of the basic mechanisms of coronary artery thrombosis
Published in Physiological research (2008)“…Tissue factor is a cell surface protein that is expressed constitutively by monocytes, macrophages and fibroblasts, but also by some other cells in response to…”
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