Search Results - "Biru, Tsigereda"

Effective and targeted latency reversal in CD4 + T cells from individuals on long term combined antiretroviral therapy initiated during chronic HIV-1 infection by Ngo, Minh Ha, Pankrac, Joshua, Ho, Ryan C Y, Ndashimye, Emmanuel, Pawa, Rahul, Ceccacci, Renata, Biru, Tsigereda, Olabode, Abayomi S, Klein, Katja, Li, Yue, Kovacs, Colin, Assad, Robert, Jacobson, Jeffrey M, Canaday, David H, Tomusange, Stephen, Jamiru, Samiri, Anok, Aggrey, Kityamuweesi, Taddeo, Buule, Paul, Galiwango, Ronald M, Reynolds, Steven J, Quinn, Thomas C, Redd, Andrew D, Prodger, Jessica L, Mann, Jamie F S, Arts, Eric J

“…To date, an affordable, effective treatment for an HIV-1 cure remains only a concept with most "latency reversal" agents (LRAs) lacking specificity for the…”
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A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system by Pankrac, Joshua, Klein, Katja, McKay, Paul F., King, Deborah F. L., Bain, Katie, Knapp, Jason, Biru, Tsigereda, Wijewardhana, Chanuka N., Pawa, Rahul, Canaday, David H., Gao, Yong, Fidler, Sarah, Shattock, Robin J., Arts, Eric J., Mann, Jamie F. S.

“…First identified as the etiological agent behind Acquired Immunodeficiency Syndrome (AIDS) in the early 1980s, HIV-1 has continued to spread into a global…”
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The anti-tumoral drug enzastaurin inhibits natural killer cell cytotoxicity via activation of glycogen synthase kinase-3β by Ogbomo, Henry, Biru, Tsigereda, Michaelis, Martin, Loeschmann, Nadine, Doerr, Hans Wilhelm, Cinatl, Jindrich

“…Enzastaurin is a selective protein kinase Cβ inhibitor which is shown to have direct antitumor effect as well as suppress glycogen synthase kinase-3β (GSK-3β)…”
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