Search Results - "Birnbaum, Mark"
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Studies of OC-STAMP in Osteoclast Fusion: A New Knockout Mouse Model, Rescue of Cell Fusion, and Transmembrane Topology
Published in PloS one (04-06-2015)“…The fusion of monocyte/macrophage lineage cells into fully active, multinucleated, bone resorbing osteoclasts is a complex cell biological phenomenon that…”
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Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation
Published in Journal of cellular physiology (01-05-2008)“…Microarray and real‐time RT‐PCR were used to examine expression changes in primary bone marrow cells and RAW 264.7 cells in response to RANKL. In silico…”
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Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation
Published in ACS chemical biology (20-10-2017)“…Histone acetyltransferases of the MYST family are recruited to chromatin by BRPF scaffolding proteins. We explored functional consequences and the therapeutic…”
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Novel Radiographic Analysis of Guided Growth for Knee Flexion Contractures: A Retrospective Analysis of Anterior-Distal Hemiepiphysiodesis of the Femur via Utilization of Blumensaat's Line
Published in Pediatrics (Evanston) (01-09-2017)“…In 2007, Stevens and Klatt introduced the guided growth concept, which advanced the surgical treatment of knee deformities, particularly in the coronal plane…”
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Outcomes After Salvage Procedures for the Painful Dislocated Hip in Cerebral Palsy
Published in Journal of pediatric orthopaedics (01-07-2013)“…BACKGROUND:The painful dislocated hip in the setting of cerebral palsy is a challenging problem. Many surgical procedures have been reported to treat this…”
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Expression of and Role for Ovarian Cancer G-protein-coupled Receptor 1 (OGR1) during Osteoclastogenesis
Published in The Journal of biological chemistry (18-08-2006)“…Osteoclasts differentiate from hematopoietic mononuclear precursor cells under the control of both colony stimulating factor-1 (CSF-1, or M-CSF) and receptor…”
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Increased Intracapsular Pressures After Unstable Slipped Capital Femoral Epiphysis
Published in Journal of pediatric orthopaedics (01-10-2008)“…BACKGROUND:Osteonecrosis of the femoral head is the most dreaded complication associated with an unstable slipped capital femoral epiphysis (SCFE). We…”
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Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless ( tl ) Osteopetrotic, Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections
Published in The American journal of pathology (01-12-2009)“…The septoclast is a specialized, cathepsin B-rich, perivascular cell type that accompanies invading capillaries on the metaphyseal side of the growth plate…”
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ISRAEL DOES NOT REPRESENT JEWISH VALUES
Published in The Washington report on Middle East affairs (01-01-2024)Get full text
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Role of apoptosis in glucocorticoid-induced osteoporosis and osteonecrosis
Published in Critical reviews in eukaryotic gene expression (2003)“…Bone disease is a side effect of concern regarding chronic glucocorticoid (GC) administration. Most GC-treated patients exhibit a process of bone loss,…”
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False-Positive β-Galactosidase Staining in Osteoclasts by Endogenous Enzyme: Studies in Neonatal and Month-Old Wild-Type Mice
Published in Connective Tissue Research (2006)“…Escherichia coli β-galactosidase (β-gal), encoded by the lacZ gene, has become an essential tool in studies of gene expression and function in higher…”
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Increased Intracapsular Pressures After Unstable Slipped Capital Femoral Epiphysis
Published in Journal of pediatric orthopaedics (01-10-2008)Get full text
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Using osteoclast differentiation as a model for gene discovery in an undergraduate cell biology laboratory
Published in Biochemistry and molecular biology education (01-11-2010)“…A key goal of molecular/cell biology/biotechnology is to identify essential genes in virtually every physiological process to uncover basic mechanisms of cell…”
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Sp1 Trans-Activation of Cell Cycle Regulated Promoters Is Selectively Repressed by Sp3
Published in Biochemistry (Easton) (19-12-1995)“…The transcription factor Sp1 plays a key role in the activation of many cellular and viral gene promoters, including those that are regulated during the cell…”
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Novel Sagittal Plane Radiographic Analysis of Guided Growth for Knee Flexion Contractures: Utilization of Blumensaat’s Line
Published in Pediatrics (Evanston) (01-07-2020)Get full text
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Can Rigid Femoral Nailing Be Used for Pediatric Femoral Shaft Fracture in Children 8 to 10 Years? Use of RIN in Patients With Femoral Shaft Fracture
Published in Journal of pediatric orthopaedics (01-07-2023)“…The treatment modalities for pediatric femoral shaft fractures are determined by their age, weight, and fracture pattern. Rigid intramedullary nailing (RIN) is…”
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Temperature-sensitive Mutations of the CKA1 Gene Reveal a Role for Casein Kinase II in Maintenance of Cell Polarity in Saccharomyces cerevisiae
Published in The Journal of biological chemistry (06-03-1998)“…Casein kinase II (CKII) of Saccharomyces cerevisiae contains two distinct catalytic subunits, α and α′, that are encoded by the CKA1 and -2genes, respectively…”
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Intracapsular Pressures After Stable Slipped Capital Femoral Epiphysis
Published in Journal of pediatric orthopaedics (01-12-2015)“…PURPOSE:Stable slipped capital femoral epiphysis (SCFE) has been shown to have a lower rate of avascular necrosis than unstable SCFE. A recent study found…”
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Biosynthesis of Osteogenic Growth Peptide via Alternative Translational Initiation at AUG85 of Histone H4 mRNA
Published in The Journal of biological chemistry (14-05-1999)“…The osteogenic growth peptide (OGP) is an extracellular mitogen identical to the histone H4 (H4) COOH-terminal residues 90–103, which regulates osteogenesis…”
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