Search Results - "Birkholz, Erica A"

The Phage Nucleus and PhuZ Spindle: Defining Features of the Subcellular Organization and Speciation of Nucleus-Forming Jumbo Phages by Chaikeeratisak, Vorrapon, Birkholz, Erica A., Pogliano, Joe

“…Bacteriophages and their bacterial hosts are ancient organisms that have been co-evolving for billions of years. Some jumbo phages, those with a genome size…”
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Selective transport of fluorescent proteins into the phage nucleus by Nguyen, Katrina T, Sugie, Joseph, Khanna, Kanika, Egan, MacKennon E, Birkholz, Erica A, Lee, Jina, Beierschmitt, Christopher, Villa, Elizabeth, Pogliano, Joe

“…Upon infection of Pseudomonas cells, jumbo phages 201Φ2-1, ΦPA3, and ΦKZ assemble a phage nucleus. Viral DNA is enclosed within the phage-encoded proteinaceous…”
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Viral speciation through subcellular genetic isolation and virogenesis incompatibility by Chaikeeratisak, Vorrapon, Birkholz, Erica A., Prichard, Amy M., Egan, MacKennon E., Mylvara, Avani, Nonejuie, Poochit, Nguyen, Katrina T., Sugie, Joseph, Meyer, Justin R., Pogliano, Joe

“…Understanding how biological species arise is critical for understanding the evolution of life on Earth. Bioinformatic analyses have recently revealed that…”
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Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity by Lau, Rebecca K., Ye, Qiaozhen, Birkholz, Erica A., Berg, Kyle R., Patel, Lucas, Mathews, Ian T., Watrous, Jeramie D., Ego, Kaori, Whiteley, Aaron T., Lowey, Brianna, Mekalanos, John J., Kranzusch, Philip J., Jain, Mohit, Pogliano, Joe, Corbett, Kevin D.

“…Bacteria possess an array of defenses against foreign invaders, including a broadly distributed bacteriophage defense system termed CBASS (cyclic…”
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HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity by Ye, Qiaozhen, Lau, Rebecca K., Mathews, Ian T., Birkholz, Erica A., Watrous, Jeramie D., Azimi, Camillia S., Pogliano, Joe, Jain, Mohit, Corbett, Kevin D.

“…Bacteria are continually challenged by foreign invaders, including bacteriophages, and have evolved a variety of defenses against these invaders. Here, we…”
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Architecture and self-assembly of the jumbo bacteriophage nuclear shell by Laughlin, Thomas G., Deep, Amar, Prichard, Amy M., Seitz, Christian, Gu, Yajie, Enustun, Eray, Suslov, Sergey, Khanna, Kanika, Birkholz, Erica A., Armbruster, Emily, McCammon, J. Andrew, Amaro, Rommie E., Pogliano, Joe, Corbett, Kevin D., Villa, Elizabeth

“…Bacteria encode myriad defences that target the genomes of infecting bacteriophage, including restriction–modification and CRISPR–Cas systems 1 . In response,…”
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An intron endonuclease facilitates interference competition between coinfecting viruses by Birkholz, Erica A, Morgan, Chase J, Laughlin, Thomas G, Lau, Rebecca K, Prichard, Amy, Rangarajan, Sahana, Meza, Gabrielle N, Lee, Jina, Armbruster, Emily, Suslov, Sergey, Pogliano, Kit, Meyer, Justin R, Villa, Elizabeth, Corbett, Kevin D, Pogliano, Joe

“…Introns containing homing endonucleases are widespread in nature and have long been assumed to be selfish elements that provide no benefit to the host…”
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A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli by Birkholz, Erica A., Laughlin, Thomas G., Armbruster, Emily, Suslov, Sergey, Lee, Jina, Wittmann, Johannes, Corbett, Kevin D., Villa, Elizabeth, Pogliano, Joe

“…Nucleus-forming jumbo phages establish an intricate subcellular organization, enclosing phage genomes within a proteinaceous shell called the phage nucleus…”
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An essential and highly selective protein import pathway encoded by nucleus-forming phage by Morgan, Chase J, Enustun, Eray, Armbruster, Emily G, Birkholz, Erica A, Prichard, Amy, Forman, Taylor, Aindow, Ann, Wannasrichan, Wichanan, Peters, Sela, Inlow, Koe, Shepherd, Isabelle L, Razavilar, Alma, Chaikeeratisak, Vorrapon, Adler, Benjamin A, Cress, Brady F, Doudna, Jennifer A, Pogliano, Kit, Villa, Elizabeth, Corbett, Kevin D, Pogliano, Joe

“…Targeting proteins to specific subcellular destinations is essential in prokaryotes, eukaryotes, and the viruses that infect them. Chimalliviridae phages…”
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Architecture and self-assembly of the jumbo phage nucleus-like compartment by Laughlin, Thomas G., Deep, Amar, Prichard, Amy M., Seitz, Christian, Gu, Yajie, Enustun, Eray, Suslov, Sergey, Khanna, Kanika, Birkholz, Erica A., Armbruster, Emily, Amaro, Rommie E., Pogliano, Joe, Corbett, Kevin D., Villa, Elizabeth

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Nucleus-Forming Jumbo Phage: Disrupting the Landscape of Phage Replication and Viral Speciation by Birkholz, Erica A

“…This dissertation investigates the diversity and competition of nucleus-forming jumbo phage. The first chapter provides a brief history of the discovery of…”
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Selective transport of fluorescent proteins into the phage nucleus by Katrina T Nguyen, Joseph Sugie, Kanika Khanna, MacKennon E Egan, Erica A Birkholz, Jina Lee, Christopher Beierschmitt, Elizabeth Villa, Joe Pogliano

“…Upon infection of Pseudomonas cells, jumbo phages 201Φ2-1, ΦPA3, and ΦKZ assemble a phage nucleus. Viral DNA is enclosed within the phage-encoded proteinaceous…”
Get full text