Search Results - "Birk, D. E."

Intrinsic aging vs. photoaging: a comparative histopathological, immunohistochemical, and ultrastructural study of skin by El-Domyati, M., Attia, S., Saleh, F., Brown, D., Birk, D. E., Gasparro, F., Ahmad, H., Uitto, J.

“…: Cutaneous aging is a complex biological phenomenon affecting the different constituents of the skin. To compare the effects of intrinsic and extrinsic aging…”
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Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model by Gordon, J.A, Freedman, B.R, Zuskov, A, Iozzo, R.V, Birk, D.E, Soslowsky, L.J

“…Abstract Achilles tendons are a common source of pain and injury, and their pathology may originate from aberrant structure function relationships. Small…”
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Type V collagen: heterotypic type I/V collagen interactions in the regulation of fibril assembly by Birk, D E

“…Type V collagen is a quantitatively minor fibrillar collagen with a broad tissue distribution. The most common type V collagen isoform is alpha1(V)(2)…”
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Differential Expression of Lumican and Fibromodulin Regulate Collagen Fibrillogenesis in Developing Mouse Tendons by Ezura, Yoichi, Chakravarti, Shukti, Oldberg, Åke, Chervoneva, Inna, Birk, David E.

“…Collagen fibrillogenesis is finely regulated during development of tissue-specific extracellular matrices. The role(s) of a leucine-rich repeat protein…”
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Corneal Opacity in Lumican-Null Mice: Defects in Collagen Fibril Structure and Packing in the Posterior Stroma by Chakravarti, Shukti, Petroll, W. Matthew, Hassell, John R, Jester, James V, Lass, Jonathan H, Paul, Jennifer, Birk, David E

“…Gene targeted lumican-null mutants (lum(tm1sc)/lum(tm1sc)) have cloudy corneas with abnormally thick collagen fibrils. The purpose of the present study was to…”
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Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis by Han, B., Li, Q., Wang, C., Chandrasekaran, P., Zhou, Y., Qin, L., Liu, X.S., Enomoto-Iwamoto, M., Kong, D., Iozzo, R.V., Birk, D.E., Han, L.

“…To delineate the activities of decorin and biglycan in the progression of post-traumatic osteoarthritis (PTOA). Three-month-old inducible biglycan (BgniKO) and…”
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Collagen Type I and Type V Are Present in the Same Fibril in the Avian Corneal Stroma by Birk, David E., Fitch, John M., Babiarz, Joanne P., Linsenmayer, Thomas F.

“…The distribution, supramolecular form, and arrangement of collagen types I and V in the chicken embryo corneal stroma were studied using electron microscopy,…”
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Extracellular Compartments in Tendon Morphogenesis: Collagen Fibril, Bundle, and Macroaggregate Formation by Birk, David E., Trelstad, Robert L.

“…The formation of collagen fibrils, fibril bundles, and tissue-specific collagen macroaggregates by chick embryo tendon fibroblasts was studied using…”
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Type V collagen: molecular structure and fibrillar organization of the chicken alpha 1(V) NH2-terminal domain, a putative regulator of corneal fibrillogenesis by Linsenmayer, T F, Gibney, E, Igoe, F, Gordon, M K, Fitch, J M, Fessler, L I, Birk, D E

“…Previous work from our laboratories has demonstrated that: (a) the striated collagen fibrils of the corneal stroma are heterotypic structures composed of type…”
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Altered Corneal Stromal Matrix Organization is Associated with Mucopolysaccharidosis I, III and VI by ALROY, JOSEPH, HASKINS, MARK, BIRK, DAVID E.

“…The presence of cloudy corneas is a prominent feature of mucopolysaccharidosis (MPS) types I and VI, but not MPS IIIA or IIIB. The cause of corneal cloudiness…”
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Collagen fibrillogenesis in vitro: interaction of types I and V collagen regulates fibril diameter by BIRK, D. E, FITCH, J. M, BABIARZ, J. P, DOANE, K. J, LINSENMAYER, T. F

“…The small-diameter fibrils of the chick corneal stroma are heterotypic, composed of both collagen types I and V. This tissue has a high concentration of type V…”
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Reduction of Type V Collagen Using a Dominant-Negative Strategy Alters the Regulation of Fibrillogenesis and Results in the Loss of Corneal-Specific Fibril Morphology by Marchant, Jeffrey K., Hahn, Rita A., Linsenmayer, Thomas F., Birk, David E.

“…A number of factors have been implicated in the regulation of tissue-specific collagen fibril diameter. Previous data suggest that assembly of heterotypic…”
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Extracellular Compartments in Matrix Morphogenesis: Collagen Fibril, Bundle, and Lamellar Formation by Corneal Fibroblasts by Birk, David E., Trelstad, Robert L.

“…The regulation of collagen fibril, bundle, and lamella formation by the corneal fibroblasts, as well as the organization of these elements into an orthogonal…”
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Collagen Fibrillogenesis in situ: Fibril Segments are Intermediates in Matrix Assembly by Birk, David E., Zycband, Emanuel I., Winkelmann, Donald A., Trelstad, Robert L.

“…The assembly of discontinuous fibril segments and bundles was studied in 14-day chicken embryo tendons by using serial sections, transmission electron…”
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Assembly of the tendon extracellular matrix during development by Birk, D E, Zycband, E

“…The assembly of the collagenous extracellular matrix during tendon development was studied to determine the mechanisms involved in collagen fibril growth…”
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Altered wound healing in mice lacking a functional osteopontin gene (spp1) by Liaw, L, Birk, D E, Ballas, C B, Whitsitt, J S, Davidson, J M, Hogan, B L

“…Osteopontin (OPN) is an arginine-glycine-aspartate (RGD)- containing glycoprotein encoded by the gene secreted phosphoprotein 1 (spp1). spp1 is expressed…”
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Type V Collagen Controls the Initiation of Collagen Fibril Assembly by Wenstrup, Richard J., Florer, Jane B., Brunskill, Eric W., Bell, Sheila M., Chervoneva, Inna, Birk, David E.

“…Vertebrate collagen fibrils are heterotypically composed of a quantitatively major and minor fibril collagen. In non-cartilaginous tissues, type I collagen…”
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Organization of collagen types I and V in the embryonic chicken cornea by Birk, DE, Fitch, JM, Linsenmayer, TF

“…The distribution and organization of type I and type V collagens were studied in the embryonic chicken cornea using anti-collagen, type specific, monoclonal…”
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Fibroblasts retain their tissue phenotype when grown in three-dimensional collagen gels by Doane, K J, Birk, D E

“…Fibroblasts are responsible for the synthesis, assembly, deposition, and organization of extracellular matrix molecules, and thus determine the morphology of…”
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Localization of collagen types I, III and V during tendon development. Changes in collagen types I and III are correlated with changes in fibril diameter by Birk, D E, Mayne, R

“…Collagen types I, III and V were localized at different stages of tendon development: a stage when tendon architecture is established, but immature (14-day), a…”
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