Search Results - "Biringer, Kamil"
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Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person
Published in The EPMA journal (01-12-2021)“…Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein homeostasis, and DNA-methylation presenting, therefore, key pathways…”
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Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine
Published in The EPMA journal (01-06-2022)“…Mitochondria are the “gatekeeper” in a wide range of cellular functions, signaling events, cell homeostasis, proliferation, and apoptosis. Consequently,…”
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Caution, “normal” BMI: health risks associated with potentially masked individual underweight—EPMA Position Paper 2021
Published in The EPMA journal (01-09-2021)“…An increasing interest in a healthy lifestyle raises questions about optimal body weight. Evidently, it should be clearly discriminated between the…”
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miRNA Expression Profiles in Luminal A Breast Cancer-Implications in Biology, Prognosis, and Prediction of Response to Hormonal Treatment
Published in International journal of molecular sciences (17-10-2020)“…Breast cancer, which is the most common malignancy in women, does not form a uniform nosological unit but represents a group of malignant diseases with…”
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Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles
Published in The EPMA journal (01-06-2021)“…Cost-efficacy of currently applied treatments is an issue in overall cancer management challenging healthcare and causing tremendous economic burden to…”
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Implications of flavonoids as potential modulators of cancer neovascularity
Published in Journal of cancer research and clinical oncology (01-12-2020)“…Purpose The formation of new blood vessels from previous ones, angiogenesis, is critical in tissue repair, expansion or remodeling in physiological processes…”
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Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression—3PM pathways
Published in The EPMA journal (01-12-2021)“…Inflammation is an essential pillar of the immune defense. On the other hand, chronic inflammation is considered a hallmark of cancer initiation and…”
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Is the Physiological Composition of the Vaginal Microbiome Altered in High-Risk HPV Infection of the Uterine Cervix?
Published in Viruses (27-09-2022)“…Background: Cervical cancer is the fourth most common malignancy and fourth leading cause of cancer death in women worldwide. More than 99.7% of cases are…”
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Droplet digital PCR analysis of CDH13 methylation status in Slovak women with invasive ductal breast cancer
Published in Scientific reports (26-06-2024)“…Identifying novel epigenetic biomarkers is a promising way to improve the clinical management of patients with breast cancer. Our study aimed to determine the…”
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Genoprotective activities of plant natural substances in cancer and chemopreventive strategies in the context of 3P medicine
Published in The EPMA journal (01-06-2020)“…Severe durable changes may occur to the DNA structure caused by exogenous and endogenous risk factors initiating the process of carcinogenesis. By evidence, a…”
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Protective Effects of Flavonoids Against Mitochondriopathies and Associated Pathologies: Focus on the Predictive Approach and Personalized Prevention
Published in International journal of molecular sciences (11-08-2021)“…Multi-factorial mitochondrial damage exhibits a “vicious circle” that leads to a progression of mitochondrial dysfunction and multi-organ adverse effects…”
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Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care
Published in The EPMA journal (14-04-2022)“…Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer management is associated with challenges considering risk…”
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13
Glycoprotein VI Gene Variants Affect Pregnancy Loss in Patients With Platelet Hyperaggregability
Published in Clinical and applied thrombosis/hemostasis (01-12-2018)“…The aim of our study was to evaluate GP6 gene in patients with sticky platelet syndrome (SPS) and fetal loss. Platelet aggregability was tested with…”
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Phytochemical-based nanodrugs going beyond the state-of-the-art in cancer management-Targeting cancer stem cells in the framework of predictive, preventive, personalized medicine
Published in Frontiers in pharmacology (23-03-2023)“…Cancer causes many deaths worldwide each year, especially due to tumor heterogeneity leading to disease progression and treatment failure. Targeted treatment…”
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Anti-prostate cancer protection and therapy in the framework of predictive, preventive and personalised medicine — comprehensive effects of phytochemicals in primary, secondary and tertiary care
Published in The EPMA journal (08-07-2022)“…According to the GLOBOCAN 2020, prostate cancer (PCa) is the most often diagnosed male cancer in 112 countries and the leading cancer-related death in 48…”
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Exploring the Bioactive Mycocompounds (Fungal Compounds) of Selected Medicinal Mushrooms and Their Potentials against HPV Infection and Associated Cancer in Humans
Published in Life (Basel, Switzerland) (01-01-2023)“…Medicinal mushrooms have been used as a medicinal tool for many centuries and, nowadays, are used in the prevention and therapy of various diseases, including…”
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Evaluating Thromboprophylaxis Strategies for High-Risk Pregnancy: A Current Perspective
Published in Pharmaceuticals (Basel, Switzerland) (13-06-2024)“…Venous thromboembolism (VTE) represents one of the leading causes of death during pregnancy. The greatest risk for it is the presence of medical or family…”
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Aronia melanocarpa L. fruit peels show anti-cancer effects in preclinical models of breast carcinoma: The perspectives in the chemoprevention and therapy modulation
Published in Frontiers in oncology (07-10-2024)“…Within oncology research, there is a high effort for new approaches to prevent and treat cancer as a life-threatening disease. Specific plant species that…”
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Therapy-resistant breast cancer in focus: Clinically relevant mitigation by flavonoids targeting cancer stem cells
Published in Frontiers in pharmacology (06-04-2023)“…Significant limitations of the reactive medical approach in breast cancer management are clearly reflected by alarming statistics recorded worldwide. According…”
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Carotenoids in Cancer Metastasis-Status Quo and Outlook
Published in Biomolecules (Basel, Switzerland) (10-12-2020)“…Metastasis represents a major obstacle in cancer treatment and the leading cause of cancer-related deaths. Therefore, the identification of compounds targeting…”
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