Search Results - "Birgitte Zeuner"

Synthesis of Human Milk Oligosaccharides: Protein Engineering Strategies for Improved Enzymatic Transglycosylation by Zeuner, Birgitte, Teze, David, Muschiol, Jan, Meyer, Anne S

“…Human milk oligosaccharides (HMOs) signify a unique group of oligosaccharides in breast milk, which is of major importance for infant health and development…”
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Prebiotic potential of pectin and pectic oligosaccharides to promote anti-inflammatory commensal bacteria in the human colon by Chung, Wing Sun Faith, Meijerink, Marjolein, Zeuner, Birgitte, Holck, Jesper, Louis, Petra, Meyer, Anne S, Wells, Jerry M, Flint, Harry J, Duncan, Sylvia H

“…Dietary plant cell wall carbohydrates are important in modulating the composition and metabolism of the complex gut microbiota, which can impact on health…”
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β-N-Acetylhexosaminidases for Carbohydrate Synthesis via Trans-Glycosylation by Jan Muschiol, Marlene Vuillemin, Anne S. Meyer, Birgitte Zeuner

“…β-N-acetylhexosaminidases (EC 3.2.1.52) are retaining hydrolases of glycoside hydrolase family 20 (GH20). These enzymes catalyze hydrolysis of terminal,…”
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It All Starts with a Sandwich: Identification of Sialidases with Trans-Glycosylation Activity by Nordvang, Rune T, Nyffenegger, Christian, Holck, Jesper, Jers, Carsten, Zeuner, Birgitte, Sundekilde, Ulrik K, Meyer, Anne S, Mikkelsen, Jørn D

“…Sialidases (3.2.1.18) may exhibit trans-sialidase activity to catalyze sialylation of lactose if the active site topology is congruent with that of the…”
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Improved Transglycosylation by a Xyloglucan-Active α-l-Fucosidase from Fusarium graminearum by Zeuner, Birgitte, Vuillemin, Marlene, Holck, Jesper, Muschiol, Jan, Meyer, Anne S

“…produces an α-l-fucosidase, FCO1, which so far appears to be the only known fungal GH29 α-l-fucosidase that catalyzes the release of fucose from fucosylated…”
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Improvement of the Transglycosylation Efficiency of a Lacto-N-Biosidase from Bifidobacterium bifidum by Protein Engineering by Vuillemin, Marlene, Holck, Jesper, Matwiejuk, Martin, Moreno Prieto, Eduardo S., Muschiol, Jan, Molnar-Gabor, Dora, Meyer, Anne S., Zeuner, Birgitte

“…The lacto-N-biosidase LnbB from Bifidobacterium bifidum JCM 1254 was engineered to improve its negligible transglycosylation efficiency with the purpose of…”
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Comparative Characterization of Aspergillus Pectin Lyases by Discriminative Substrate Degradation Profiling by Zeuner, Birgitte, Thomsen, Thore Bach, Stringer, Mary Ann, Krogh, Kristian B. R. M., Meyer, Anne S., Holck, Jesper

“…Fungal genomes often contain several copies of genes that encode carbohydrate active enzymes having similar activity. The copies usually have slight sequence…”
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Characterization and immobilization of engineered sialidases from Trypanosoma rangeli for transsialylation by Zeuner, Birgitte, González-Delgado, Isabel, Holck, Jesper, Morales, Gabriel, López-Muñoz, María-José, Segura, Yolanda, S. Meyer, Anne, Dalgaard Mikkelsen, Jørn

“…A sialidase (EC 3.2.1.18; GH 33) from non-pathogenic Trypanosoma rangeli has been engineered with the aim of improving its transsialylation activity. Recently,…”
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Bio-based surfactants: enzymatic functionalization and production from renewable resources by Agger, Jane W, Zeuner, Birgitte

“…Bio-based surfactants produced from renewable resources are increasing in market demand. In this review, we focus on enzymatic functionalization and coupling…”
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Enzymatic transfucosylation for synthesis of human milk oligosaccharides by Zeuner, Birgitte, Meyer, Anne S.

“…Human milk oligosaccharides (HMOs) are a family of structurally distinct carbohydrate oligomers present in human milk. HMOs protect breastfed babies against…”
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Substrate specificity and transglycosylation capacity of α-L-fucosidases across GH29 assessed by bioinformatics-assisted selection of functional diversity by Perna, Valentina N, Barrett, Kristian, Meyer, Anne S, Zeuner, Birgitte

“…Abstract Glycoside hydrolase family 29 (GH29) encompasses α-L-fucosidases, i.e. enzymes that catalyze the hydrolytic release of fucose from fucosylated…”
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Loop engineering of an α-1,3/4-l-fucosidase for improved synthesis of human milk oligosaccharides by Zeuner, Birgitte, Vuillemin, Marlene, Holck, Jesper, Muschiol, Jan, Meyer, Anne S.

“…[Display omitted] •Targeted loop engineering of a GH29 fucosidase for improved transfucosylation.•3-fold yield increase in the enzyme’s conversion efficacy on…”
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Improved Enzymatic Production of the Fucosylated Human Milk Oligosaccharide LNFP II with GH29B α‑1,3/4‑l‑Fucosidases by Yang, Yaya, Thorhallsson, Albert Thor, Rovira, Carme, Holck, Jesper, Meyer, Anne S., Yang, Huan, Zeuner, Birgitte

“…Five GH29B α-1,3/4-l-fucosidases (EC 3.2.1.111) were investigated for their ability to catalyze the formation of the human milk oligosaccharide…”
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Correction to “Improved Enzymatic Production of the Fucosylated Human Milk Oligosaccharide LNFP II with GH29B α‑1,3/4-L-Fucosidases” by Yang, Yaya, Thorhallsson, Albert Thor, Rovira, Carme, Holck, Jesper, Meyer, Anne S., Yang, Huan, Zeuner, Birgitte

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Bioinformatics-based identification of GH12 endoxyloglucanases in citrus-pathogenic Penicillium spp by Li, Kai, Barrett, Kristian, Agger, Jane W., Zeuner, Birgitte, Meyer, Anne S.

“…Millions of tons of citrus peel waste are produced every year as a byproduct of the juice industry. Citrus peel is rich in pectin and xyloglucan, but while the…”
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Methods for Improving Enzymatic Trans-glycosylation for Synthesis of Human Milk Oligosaccharide Biomimetics by Zeuner, Birgitte, Jers, Carsten, Mikkelsen, Jørn Dalgaard, Meyer, Anne S

“…Recently, significant progress has been made within enzymatic synthesis of biomimetic, functional glycans, including, for example, human milk oligosaccharides…”
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Discovery of Lacto-N-biosidases and a Novel N-Acetyllactosaminidase Activity in the CAZy Family GH20: Functional Diversity and Structural Insights by Vuillemin, Marlene, Muschiol, Jan, Zhang, Yan, Holck, Jesper, Barrett, Kristian, Morth, Jens Preben, Meyer, Anne S, Zeuner, Birgitte

“…The glycoside hydrolase family 20 (GH20) predominantly features N-acetylhexosaminidases (EC 3.2.1.52), with only few known lacto-N-biosidases (EC 3.2.1.140;…”
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Substrate specificity and transfucosylation activity of GH29 α-l-fucosidases for enzymatic production of human milk oligosaccharides by Zeuner, Birgitte, Muschiol, Jan, Holck, Jesper, Lezyk, Mateusz, Gedde, Mattias Raae, Jers, Carsten, Mikkelsen, Jørn Dalgaard, Meyer, Anne S.

“…[Display omitted] •Seven GH29 α-l-fucosidases all possess transfucosylation activity.•α-l-Fucosidase from F. graminearum catalyses formation of 2′FL from…”
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Separation of phenolic acids from monosaccharides by low-pressure nanofiltration integrated with laccase pre-treatments by Luo, Jianquan, Zeuner, Birgitte, Morthensen, Sofie T., Meyer, Anne S., Pinelo, Manuel

“…Separation of phenolic acids from monosaccharides is required for detoxification of lignocellulosic hydrolysates. For the first time, a low-pressure…”
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Juice clarification by protease and pectinase treatments indicates new roles of pectin and protein in cherry juice turbidity by Pinelo, Manuel, Zeuner, Birgitte, Meyer, Anne S.

“…Industrial juice clarification is accomplished by a combination of enzymatic depectinization, gelatin–silica sol, and/or bentonite treatment. The…”
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