Search Results - "Bird, Alan"

Therapeutic targets in age-related macular disease by Bird, Alan C

“…Age-related macular disease (AMD) accounts for more than 50% of blind registration in Western society. Patients with AMD are classified as having early…”
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Geographic atrophy: a histopathological assessment by Bird, Alan C, Phillips, Rachel L, Hageman, Gregory S

“…Geographic atrophy (GA) is the major cause of blind registration in Western communities, although, with few exceptions, it is less common than choroidal…”
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The X-linked retinopathies: Physiological insights, pathogenic mechanisms, phenotypic features and novel therapies by De Silva, Samantha R., Arno, Gavin, Robson, Anthony G., Fakin, Ana, Pontikos, Nikolas, Mohamed, Moin D., Bird, Alan C., Moore, Anthony T., Michaelides, Michel, Webster, Andrew R., Mahroo, Omar A.

“…X-linked retinopathies represent a significant proportion of monogenic retinal disease. They include progressive and stationary conditions, with and without…”
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Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3 by Sadda, Srinivas R, Guymer, Robyn, Holz, Frank G, Schmitz-Valckenberg, Steffen, Curcio, Christine A, Bird, Alan C, Blodi, Barbara A, Bottoni, Ferdinando, Chakravarthy, Usha, Chew, Emily Y, Csaky, Karl, Danis, Ronald P, Fleckenstein, Monika, Freund, K Bailey, Grunwald, Juan, Hoyng, Carel B, Jaffe, Glenn J, Liakopoulos, Sandra, Monés, Jordi M, Pauleikhoff, Daniel, Rosenfeld, Philip J, Sarraf, David, Spaide, Richard F, Tadayoni, Ramin, Tufail, Adnan, Wolf, Sebastian, Staurenghi, Giovanni

“…To develop consensus terminology and criteria for defining atrophy based on OCT findings in the setting of age-related macular degeneration (AMD). Consensus…”
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Macular telangiectasia type 2 by Charbel Issa, Peter, Gillies, Mark C., Chew, Emily Y., Bird, Alan C., Heeren, Tjebo F.C., Peto, Tunde, Holz, Frank G., Scholl, Hendrik P.N.

“…Macular telangiectasia type 2 is a bilateral disease of unknown cause with characteristic alterations of the macular capillary network and neurosensory…”
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Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 4 by Guymer, Robyn H, Rosenfeld, Philip J, Curcio, Christine A, Holz, Frank G, Staurenghi, Giovanni, Freund, K Bailey, Schmitz-Valckenberg, Steffen, Sparrow, Janet, Spaide, Richard F, Tufail, Adnan, Chakravarthy, Usha, Jaffe, Glenn J, Csaky, Karl, Sarraf, David, Monés, Jordi M, Tadayoni, Ramin, Grunwald, Juan, Bottoni, Ferdinando, Liakopoulos, Sandra, Pauleikhoff, Daniel, Pagliarini, Sergio, Chew, Emily Y, Viola, Francesco, Fleckenstein, Monika, Blodi, Barbara A, Lim, Tock Han, Chong, Victor, Lutty, Jerry, Bird, Alan C, Sadda, Srinivas R

“…To describe the defining features of incomplete retinal pigment epithelium (RPE) and outer retinal atrophy (iRORA), a consensus term referring to the OCT-based…”
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Clinical Classification of Age-related Macular Degeneration by Ferris, Frederick L., MD, Wilkinson, C.P., MD, Bird, Alan, MD, Chakravarthy, Usha, MD, Chew, Emily, MD, Csaky, Karl, MD, Sadda, SriniVas R., MD

“…Objective To develop a clinical classification system for age-related macular degeneration (AMD). Design Evidence-based investigation, using a modified Delphi…”
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A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration–Like Lesions at the Peripheral Retina by Lengyel, Imre, PhD, Csutak, Adrienne, MD, PhD, Florea, Daniela, PhD, Leung, Irene, BA, Bird, Alan C., MD, Jonasson, Fridbert, MD, Peto, Tunde, MD, PhD

“…Purpose Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in…”
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Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings by Holz, Frank G, Sadda, SriniVas R, Staurenghi, Giovanni, Lindner, Moritz, Bird, Alan C, Blodi, Barbara A, Bottoni, Ferdinando, Chakravarthy, Usha, Chew, Emily Y, Csaky, Karl, Curcio, Christine A, Danis, Ron, Fleckenstein, Monika, Freund, K Bailey, Grunwald, Juan, Guymer, Robyn, Hoyng, Carel B, Jaffe, Glenn J, Liakopoulos, Sandra, Monés, Jordi M, Oishi, Akio, Pauleikhoff, Daniel, Rosenfeld, Philip J, Sarraf, David, Spaide, Richard F, Tadayoni, Ramin, Tufail, Adnan, Wolf, Sebastian, Schmitz-Valckenberg, Steffen

“…To summarize the results of 2 consensus meetings (Classification of Atrophy Meeting [CAM]) on conventional and advanced imaging modalities used to detect and…”
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Fundus autofluorescence imaging: review and perspectives by Schmitz-Valckenberg, Steffen, Holz, Frank G, Bird, Alan C, Spaide, Richard F

“…Fundus autofluorescence (FAF) imaging is a novel imaging method that allows topographic mapping of lipofuscin distribution in the retinal pigment epithelium…”
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Investigate Oral Zinc as a Prophylactic Treatment for Those at Risk for COVID-19 by McPherson, Scott W., Keunen, Jan E., Bird, Alan C., Chew, Emily Y., van Kuijk, Frederik J.

“…A very recent report identified the interaction between the receptor-binding domain of the spike glycoprotein (S protein) of SARS-CoV-2 and the peptidase…”
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Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye by Thompson, Richard B., Reffatto, Valentina, Bundy, Jacob G., Kortvely, Elod, Flinn, Jane M., Lanzirotti, Antonio, Jones, Emrys A., McPhail, David S., Fearn, Sarah, Boldt, Karsten, Ueffing, Marius, Ratu, Savanjeet Guy Singh, Pauleikhoff, Laurenz, Bird, Alan C., Lengyel, Imre

“…Significance Proteins and lipids accumulating in deposits external to the retinal pigment epithelium (RPE) represent a barrier to metabolic exchange between…”
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Perspectives on Reticular Pseudodrusen in Age-Related Macular Degeneration by Sivaprasad, Sobha, FRCOphth, Bird, Alan, FRCOphth, Nitiahpapand, Rynda, BSc, Nicholson, Luke, FRCOphth, Hykin, Phil, FRCOphth, Chatziralli, Irini, MD, PhD

“…Abstract Drusen have been considered the clinical hallmark of age-related macular degeneration (AMD). Reticular pseudodrusen (RPD), although first described…”
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Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration by Holz, Frank G., MD, FEBO, Sadda, SriniVas R., MD, Staurenghi, Giovanni, MD, FARVO, Lindner, Moritz, MD, Bird, Alan C., MD, FARVO, Blodi, Barbara A., MD, Bottoni, Ferdinando, MD, FEBO, Chakravarthy, Usha, MBBS, PhD, Chew, Emily Y., MD, FARVO, Csaky, Karl, MD, PhD, Curcio, Christine A., PhD, FARVO, Danis, Ron, MD, Fleckenstein, Monika, MD, Freund, K. Bailey, MD, Grunwald, Juan, MD, Guymer, Robyn, MBBS, PhD, Hoyng, Carel B., MD, PhD, Jaffe, Glenn J., MD, FARVO, Liakopoulos, Sandra, MD, Monés, Jordi M., MD, PhD, Oishi, Akio, MD, PhD, Pauleikhoff, Daniel, MD, Rosenfeld, Philip J., MD, PhD, Sarraf, David, MD, Spaide, Richard F., MD, Tadayoni, Ramin, MD, PhD, Tufail, Adnan, MD, FRCOphth, Wolf, Sebastian, MD, PhD, Schmitz-Valckenberg, Steffen, MD, FEBO

“…Purpose To summarize the results of 2 consensus meetings (Classification of Atrophy Meeting [CAM]) on conventional and advanced imaging modalities used to…”
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Progression of Vision Loss in Macular Telangiectasia Type 2 by Heeren, Tjebo F C, Clemons, Traci, Scholl, Hendrik P N, Bird, Alan C, Holz, Frank G, Charbel Issa, Peter

“…To investigate progressive vision loss in patients with macular telangiectasia (MacTel) type 2 and to compare the ability to detect functional decline between…”
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Ciliary Neurotrophic Factor for Macular Telangiectasia Type 2: Results From a Phase 1 Safety Trial by Chew, Emily Y, Clemons, Traci E, Peto, Tunde, Sallo, Ferenc B, Ingerman, Avner, Tao, Weng, Singerman, Lawrence, Schwartz, Steven D, Peachey, Neal S, Bird, Alan C

“…Purpose To evaluate the safety and tolerability of intraocular delivery of ciliary neurotrophic factor (CNTF) using an encapsulated cell implant for the…”
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Complement C3 Variant and the Risk of Age-Related Macular Degeneration by Yates, John R.W, Sepp, Tiina, Matharu, Baljinder K, Khan, Jane C, Thurlby, Deborah A, Shahid, Humma, Clayton, David G, Hayward, Caroline, Morgan, Joanne, Wright, Alan F, Armbrecht, Ana Maria, Dhillon, Baljean, Deary, Ian J, Redmond, Elizabeth, Bird, Alan C, Moore, Anthony T

“…A variant on complement factor 3 is associated with age-related macular degeneration, with a population attributable risk of 22%. This finding underlines the…”
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Scotopic thresholds on dark-adapted chromatic perimetry in healthy aging and age-related macular degeneration by Grewal, Manjot Kaur, Chandra, Shruti, Bird, Alan, Jeffery, Glen, Sivaprasad, Sobha

“…To evaluate the effect of aging, intra- and intersession repeatability and regional scotopic sensitivities in healthy and age-related macular degeneration…”
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Idiopathic multifocal choroiditis: a comment on present and past nomenclature by Essex, Rohan W, Wong, James, Jampol, Lee M, Dowler, Jonathan, Bird, Alan C

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LONGITUDINAL CORRELATION OF ELLIPSOID ZONE LOSS AND FUNCTIONAL LOSS IN MACULAR TELANGIECTASIA TYPE 2 by Heeren, Tjebo F C, Kitka, Diána, Florea, Daniela, Clemons, Traci E, Chew, Emily Y, Bird, Alan C, Pauleikhoff, Daniel, Issa, Peter Charbel, Holz, Frank G, Peto, Tunde

“…To compare ellipsoid zone (EZ) loss and functional loss in macular telangiectasia (MacTel) type 2 longitudinally. Prospective natural history study. Ellipsoid…”
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