Search Results - "Birch, Rolfe"

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain by Chessell, Iain P., Hatcher, Jonathan P., Bountra, Chas, Michel, Anton D., Hughes, Jane P., Green, Paula, Egerton, Julie, Murfin, Melanie, Richardson, Jill, Peck, Wendy L., Grahames, Caroline B.A., Casula, Maria Anna, Yiangou, Yiangos, Birch, Rolfe, Anand, Praveen, Buell, Gary N.

“…The P2X7 purinoceptor is a ligand-gated cation channel, expressed predominantly by cells of immune origin, with a unique phenotype which includes release of…”
Get full text

Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy by Facer, Paul, Casula, Maria A, Smith, Graham D, Benham, Christopher D, Chessell, Iain P, Bountra, Chas, Sinisi, Marco, Birch, Rolfe, Anand, Praveen

“…Transient receptor potential (TRP) receptors expressed by primary sensory neurons mediate thermosensitivity, and may play a role in sensory pathophysiology. We…”
Get full text

Trench Foot or Non-Freezing Cold Injury As a Painful Vaso-Neuropathy: Clinical and Skin Biopsy Assessments by Anand, Praveen, Privitera, Rosario, Yiangou, Yiangos, Donatien, Philippe, Birch, Rolfe, Misra, Peter

“…Trench foot, or non-freezing cold injury (NFCI), results from cold exposure of sufficient severity and duration above freezing point, with consequent sensory…”
Get full text

Peroneal intraneural ganglia: the importance of the articular branch. Clinical series by SPINNER, Robert J, ATKINSON, John L. D, SCHEITHAUER, Bernd W, ROCK, Michael G, BIRCH, Rolfe, KIM, Thomas A, KLIOT, Michel, KLINE, David G, TIEL, Robert L

“…The peroneal nerve is the most common site of intraneural ganglia. The neurological deficit associated with these cysts is often severe and the operation to…”
Get full text

Brachial Plexus Injury: The London Experience with Supraclavicular Traction Lesions by Birch, Rolfe, MChir, FRCS&P (Glas), FRCS (Edin), FRCS (Eng)

“…In this article, the author details the experiences of his hospital and other London hospitals in treating brachial plexus injury. As noted, important advances…”
Get full text

Iatrogenous lesions of nerves and arteries in the leg and foot by Birch, Rolfe, MChir, FRCS

Get full text

Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study by Durrenberger, Pascal F, Facer, Paul, Casula, Maria A, Yiangou, Yiangos, Gray, Roy A, Chessell, Iain P, Day, Nicola C, Collins, Sue D, Bingham, Sharon, Wilson, Alex W, Elliot, David, Birch, Rolfe, Anand, Praveen

“…Recent studies show that inflammatory processes may contribute to neuropathic pain. Cyclooxygenase-2 (Cox-2) is an inducible enzyme responsible for production…”
Get full text

Long-term trans-synaptic glial responses in the human thalamus after peripheral nerve injury by Banati, Richard B, Cagnin, Annachiara, Brooks, David J, Gunn, Roger N, Myers, Ralph, Jones, Terry, Birch, Rolfe, Anand, Praveen

“…Limb denervation leads to reorganization of the representational zones of the somatosensory cortex. Using [C](R)-PK11195, a sensitive in vivo marker of glial…”
Get full text

Increased acid-sensing ion channel ASIC-3 in inflamed human intestine by YIANGOS YIANGOU, FACER, Paul, SMITH, Jacqueline A. M, SANGAMESWARAN, Lakshmi, EGLEN, Richard, BIRCH, Rolfe, KNOWLES, Charles, WILLIAMS, Norman, ANAND, Praveen

“…Acid-sensing ion channels (ASICs) are expressed by rat sensory neurons and may mediate pain associated with tissue acidosis after inflammation or injury. Our…”
Get full text

Nerve fibers in lumbar spine structures and injured spinal roots express the sensory neuron-specific sodium channels SNS/PN3 and NaN/SNS2 by BUCKNILL, Andrew T, COWARD, Kevin, PLUMPTON, Christopher, TATE, Simon, BOUNTRA, Chas, BIRCH, Rolfe, SANDISON, Ann, HUGHES, Sean P. F, ANAND, Praveen

“…This prospective study examined the innervation of lumbar spine in tissues from patients with lower back pain and spine nerve roots from patients with…”
Get full text

Cyclooxygenase-2 (Cox-2) in injured human nerve and a rat model of nerve injury by Durrenberger, Pascal F., Facer, Paul, Gray, Roy  A., Chessell, Iain P., Naylor, Alan, Bountra, Chas, Banati, Richard B., Birch, Rolfe, Anand, Praveen

“…Inflammation associated with nerve injury produces a number of pathogenic chemical mediators of which prostanoids are a potent component. Cyclooxygenases…”
Get full text

CAUSALGIA: A RESTATEMENT by BIRCH, Rolfe

“…Forty-eight cases of causalgia are described. The syndrome was caused by missile injury in 33 patients. There was a major arterial injury in 22 patients…”
Get full text

Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial by Berman, Jonathan S., Symonds, Catherine, Birch, Rolfe

“…The objective was to investigate the effectiveness of cannabis-based medicines for treatment of chronic pain associated with brachial plexus root avulsion…”
Get full text

Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons by Anand, Uma, Otto, William R., Sanchez-Herrera, Daniel, Facer, Paul, Yiangou, Yiangos, Korchev, Yuri, Birch, Rolfe, Benham, Christopher, Bountra, Chas, Chessell, Iain P., Anand, Praveen

“…Cannabinoid receptor 2 (CB2) agonists provide the potential for treating chronic pain states without CNS effects associated with CB1 receptor activation…”
Get full text

Capsaicin 8% patch treatment for amputation stump and phantom limb pain: a clinical and functional MRI study by Privitera, Rosario, Birch, Rolfe, Sinisi, Marco, Mihaylov, Iordan R, Leech, Robert, Anand, Praveen

“…The aim of this study was to measure the efficacy of a single 60 min application of capsaicin 8% patch in reducing chronic amputation stump and phantom limb…”
Get full text

The examination and management of nerve injury in supracondylar fractures of the humerus by Quick, Tom J, Macquillan, Anthony, Sinisi, Marco, Fox, Mike, Birch, Rolfe

Get full text

Peripheral nerve palsies associated with closed fractures and dislocations by Kato, Naoki, Birch, Rolfe

“…We have studied 178 consecutive cases of 203 patients admitted to this unit between 1999 and 2003 with diagnosis of peripheral nerve palsies associated with…”
Get full text

Localized and non-contact mechanical stimulation of dorsal root ganglion sensory neurons using scanning ion conductance microscopy by Sánchez, Daniel, Anand, Uma, Gorelik, Julia, Benham, Christopher D., Bountra, Chas, Lab, Max, Klenerman, David, Birch, Rolfe, Anand, Praveen, Korchev, Yuri

“…Mechanosensitive ion channels convert external mechanical force into electrical and chemical signals in cells, but their physiological function in different…”
Get full text

Commentary 1.5 - The reaction of peripheral nerves to injury by Birch, Rolfe, Anand, Praveen

Get full text

Increased levels of SV2A botulinum neurotoxin receptor in clinical sensory disorders and functional effects of botulinum toxins A and E in cultured human sensory neurons by Yiangou, Yiangos, Anand, Uma, Otto, William R, Sinisi, Marco, Fox, Michael, Birch, Rolfe, Foster, Keith A, Mukerji, Gaurav, Akbar, Ayesha, Agarwal, Sanjiv K, Anand, Praveen

“…There is increasing evidence that botulinum neurotoxin A may affect sensory nociceptor fibers, but the expression of its receptors in clinical pain states, and…”
Get full text