Search Results - "Birch, Louise M"
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The design and synthesis of inhibitors of pantothenate synthetase
Published in Organic & biomolecular chemistry (01-01-2006)“…Pantothenate synthetase catalyses the ATP-dependent condensation of D-pantoate and beta-alanine to form pantothenate. Ten analogues of the reaction…”
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2
Identification of Tyr58 as the proton donor in the aspartate-alpha-decarboxylase reaction
Published in Chemical communications (Cambridge, England) (21-09-2001)“…The decarboxylation of L-aspartate by E. coli L-aspartate-alpha-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein…”
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Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites
Published in Structure (London) (01-08-2003)“…We report the crystal structure of E. coli ketopantoate hydroxymethyltransferase (KPHMT) at 1.9 A resolution, in complex with its product, ketopantoate. KPHMT…”
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Structure of E. coli Ketopantoate Hydroxymethyl Transferase Complexed with Ketopantoate and Mg 2+, Solved by Locating 160 Selenomethionine Sites
Published in Structure (London) (2003)“…We report the crystal structure of E. coli ketopantoate hydroxymethyltransferase (KPHMT) at 1.9 Å resolution, in complex with its product, ketopantoate. KPHMT…”
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Journal Article