Search Results - "Biophysical chemistry"

Self-assembly of surfactants: An overview on general aspects of amphiphiles by Ghosh, Sampad, Ray, Anirban, Pramanik, Nabakumar

“…Surfactants are molecules (ionic or nonionic) that upon adsorption at the air-water interface reduce surface tension of water. Therefore, surfactants are…”
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Biophysical processes underlying cross-seeding in amyloid aggregation and implications in amyloid pathology by Ivanova, Magdalena I., Lin, Yuxi, Lee, Young-Ho, Zheng, Jie, Ramamoorthy, Ayyalusamy

“…Abnormal aggregation of proteins into filamentous aggregates commonly associates with many diseases, such as Alzheimer’s disease, Parkinson’s disease and…”
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Visualizing and trapping transient oligomers in amyloid assembly pathways by Cawood, Emma E., Karamanos, Theodoros K., Wilson, Andrew J., Radford, Sheena E.

“…Oligomers which form during amyloid fibril assembly are considered to be key contributors towards amyloid disease. However, understanding how such…”
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Therapeutic potential of graphitic carbon nitride as a drug delivery system for cisplatin (anticancer drug): A DFT approach by Perveen, Mehvish, Nazir, Sidra, Arshad, Ahmad Wahab, Khan, Muhammad Issa, Shamim, Maria, Ayub, Khurshid, Khan, Muhammad Asif, Iqbal, Javed

“…In the current study, for the first time; the drug loading efficacy of graphitic‑carbon nitride (g-C3N4) for an anticancer drug, cisplatin was evaluated. To…”
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Structures of the intrinsically disordered Aβ, tau and α-synuclein proteins in aqueous solution from computer simulations by Nguyen, Phuong H., Derreumaux, Philippe

“…[Display omitted] •IDPs are involved in neurodegenerative diseases.•Structure determination of the Aβ, tau and α-synuclein proteins is a challenge.•Computer…”
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Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods by Poustforoosh, Alireza, Hashemipour, Hassan, Tüzün, Burak, Pardakhty, Abbas, Mehrabani, Mehrnaz, Nematollahi, Mohammad Hadi

“…Despite all the efforts to treat COVID-19, no particular cure has been found for this virus. Since developing antiviral drugs is a time-consuming process, the…”
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The role of surfaces on amyloid formation by Grigolato, Fulvio, Arosio, Paolo

“…Interfaces can strongly accelerate or inhibit protein aggregation, destabilizing proteins that are stable in solution or, conversely, stabilizing proteins that…”
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Reckoning a fungal metabolite, Pyranonigrin A as a potential Main protease (Mpro) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation by Rao, Priyashi, Shukla, Arpit, Parmar, Paritosh, Rawal, Rakesh M., Patel, Baldev, Saraf, Meenu, Goswami, Dweipayan

“…The novel SARS-CoV-2 is the etiological agent causing the Coronavirus disease 2019 (COVID-19), which continues to become an inevitable pandemic outbreak. Over…”
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Transient disorder along pathways to amyloid by Morgan, Gareth J.

“…High-resolution structures of amyloid fibrils formed from normally-folded proteins have revealed non-native conformations of the polypeptide chains. Attaining…”
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The role of water in the primary nucleation of protein amyloid aggregation by Camino, José D., Gracia, Pablo, Cremades, Nunilo

“…The understanding of the complex conformational landscape of amyloid aggregation and its modulation by relevant physicochemical and cellular factors is a…”
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A mechanistic survey of Alzheimer's disease by Tang, Yijing, Zhang, Dong, Gong, Xiong, Zheng, Jie

“…Alzheimer's disease (AD) is the most common, age-dependent neurodegenerative disorder. While AD has been intensively studied from different aspects, there is…”
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Intrinsically disordered proteins/regions and insight into their biomolecular interactions by Chakrabarti, Pinak, Chakravarty, Devlina

“…Proteins may vary from being rigid to having flexible regions to being completely disordered, either as an intrinsically disordered protein (IDP) or having…”
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Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods by Bursal, Ercan, Yılmaz, Mustafa Abdullah, Izol, Ebubekir, Türkan, Fikret, Atalar, Mehmet Nuri, Murahari, Manikanta, Aras, Abdülmelik, Ahmad, Mushtaq

“…Many plant species have a large diversity of secondary metabolites with different biological activities. This study aims to assess the phenolic constituent,…”
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Cell membrane causes the lipid bilayers to behave as variable capacitors: A resonance with self-induction of helical proteins by Monajjemi, Majid

“…Cell membrane has a unique feature of storing biological energies in a physiologically relevant environment. This study illustrates a capacitor model of…”
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Kinetics theories to understand the mechanism of aggregation of a protein and to design strategies for its inhibition by Sharma, Shilpa, Modi, Priya, Sharma, Gargi, Deep, Shashank

“…Protein aggregation phenomenon is closely related to the formation of amyloids which results in many neurodegenerative diseases like Alzheimer's, Parkinson's,…”
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Protective effect of quercetin and rutin encapsulated liposomes on induced oxidative stress by Bonechi, Claudia, Donati, Alessandro, Tamasi, Gabriella, Leone, Gemma, Consumi, Marco, Rossi, Claudio, Lamponi, Stefania, Magnani, Agnese

“…Natural antioxidants show many pharmacological properties, but poor solubility and inability to cross cell membrane. Liposomes are biocompatible and…”
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Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain by Mukherjee, Shruti, Bhattacharyya, Dipita, Bhunia, Anirban

“…The Envelope (E) protein in SARS Coronavirus (CoV) is a small structural protein, incorporated as part of the envelope. A major fraction of the protein has…”
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Chemical characterization of liposomes containing nutraceutical compounds: Tyrosol, hydroxytyrosol and oleuropein by Bonechi, Claudia, Donati, Alessandro, Tamasi, Gabriella, Pardini, Alessio, Rostom, Hanzadah, Leone, Gemma, Lamponi, Stefania, Consumi, Marco, Magnani, Agnese, Rossi, Claudio

“…Tyrosol, hydroxytyrosol and oleuropein are among the major phenolic compounds in fruits, leaves and oils from Olea europaea L. These natural antioxidants…”
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The role of the lipid environment in the activity of G protein coupled receptors by Baccouch, Rim, Rascol, Estelle, Stoklosa, Kaja, Alves, Isabel D.

“…G protein coupled receptors (GPCRs) are a class of membrane proteins that sense extracellular signals ranging from light to odorants and small molecules and…”
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Allostery, and how to define and measure signal transduction by Nussinov, Ruth, Tsai, Chung-Jung, Jang, Hyunbum

“…Here we ask: What is productive signaling? How to define it, how to measure it, and most of all, what are the parameters that determine it? Further, what…”
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