Search Results - "Bioorganicheskaia khimiia"
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Streptokinase and Staphylokinase: Differences in the Kinetics and Mechanism of Their Interaction with Plasminogen, Inhibitors and Fibrin
Published in Bioorganicheskaia khimiia (01-09-2015)“…Comparative in vitro study of the kinetics of various reactions involved in the process of thrombolysis initiated by streptokinase (SK) and staphylokinase…”
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IDENTIFCATION AND VALIDATION OF NOVEL microRNA MOLECULE FROM THE PELODISCUS SINENSIS BY BIOINFORMATICS APPROACHES
Published in Bioorganicheskaia khimiia (01-07-2015)“…MicroRNAs (miRNAs) are a group of endogenous, short non-coding RNAs with the length of about 22 nt, which mediate gene expression at the post-transcriptional…”
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3
The Qualitative Analysis of the Amide Derivative of HLDF-6 Peptide and Its Metabolites with the Use of Tritium- and Deuterium-Labeled Derivatives
Published in Bioorganicheskaia khimiia (01-11-2015)“…The goal of the study was to elaborate the pharmacokinetics methods of the amide derivative of peptide HLDF-6 (TGENHR-NH2) and its range of nootropic and…”
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4
PiRNAs biogenesis and its functions
Published in Bioorganicheskaia khimiia (01-05-2014)“…piRNAs (piwi-interacting RNA) are a novel class of non-coding small single-stranded RNAs with the length of 26-33 nt. The piRNAs play important biological role…”
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5
Immunization witha synthetic fragment 155-164 of neurotrophin receptor p75 prevents memory loss and decreases beta-amyloid level in mice with experimentally induced Alzheimer's disease
Published in Bioorganicheskaia khimiia (01-07-2014)“…Neurotoxic beta-amyloid peptide plays an important role in the pathology of Alzheimer's disease. In aggregated form it binds to several proteins on the surface…”
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Preparation of Transmembrane Fragments Growth Hormone Receptor GHR in a Cell-Free Expression System for Structural Studies
Published in Bioorganicheskaia khimiia (01-11-2015)“…Growth hormone somatotropin and its membrane receptor GHR, belonging to a superfamily of the type I receptors possessing tyrosine kinase activity, are involved…”
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Functionalized Metal Chelates Based on Diethylenetriaminetetraacetic Acids for Chemical Modification of Proteins and Small Biomolecules
Published in Bioorganicheskaia khimiia (01-11-2015)“…Bifunctional reagents based on diethylenetriaminetetraacetic acid containing a bound metal ion and a reactive functional group for the interaction with…”
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SYNTHESIS AND BIOLOGICAL EFFICACY OF NOVEL PIPERAZINE ANALOGUES BEARING QUINOLINE AND PYRIDINE MOIETIES
Published in Bioorganicheskaia khimiia (01-09-2015)“…A series of novel piperazine analogues bearing quinolin-8-yloxy-butan--ones/pyridin-2-yloxy-ethanones were synthesized by a simple and convenient approach…”
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Protein Identification of Blood Nucleoprotein Complexes
Published in Bioorganicheskaia khimiia (01-11-2015)“…Circulating nucleoprotein complexes were isolated-from blood plasma by affinity chromatography using immobilized polyclonal anti-histone antibodies. It was…”
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10
Modulation of Ca(2+)-Dependent Proteiolysis under the Action of Weak Low-Frequency Magnetic Fields
Published in Bioorganicheskaia khimiia (01-11-2015)“…The study aimed to determine the molecular targets of magnetic fields in living objects. Time-dependent effects of weak low-frequency magnetic field tuned to…”
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11
Fragment of Receptor for Advanced Glycation End Products Improves Memory State in a Model of Alzheimer's Disease
Published in Bioorganicheskaia khimiia (01-11-2015)“…A number of synthetic peptides corresponding to potentially important regions in the sequence of the four membrane proteins known as beta-amyloid cell…”
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12
Interaction of Arenicin-1 with C1q Protein
Published in Bioorganicheskaia khimiia (01-11-2015)“…The interaction between arenicin-1, that is an antimicrobial peptide from polychaeta Arenicola marina, and human complement system protein C1q was studied…”
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13
Synthesis and Neurotropic Activity of 2,4-pyrano[4',3':4,5pyrido[2,3-bthieno[3,2-dPyrimidines
Published in Bioorganicheskaia khimiia (01-11-2015)“…2,4-Disubstituted derivatives of pyrano[4',3':4,5]pyrido[2,3-b]thieno[3,2-d] pyrimidines were synthesized and their pharmacological studies was carried out at…”
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14
Intracellular Protein Degradation in Growth of Atlantic Salmon, Salmo salar L
Published in Bioorganicheskaia khimiia (01-11-2015)“…A brief review on the common characteristics and specific features of proteolytic machinery in fish skeletal muscles (based on Atlantic salmon, Salmo salar L.,…”
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15
Ph-Sensor Properties of a Fluorescent Protein from Dendronephthya sp
Published in Bioorganicheskaia khimiia (01-11-2015)“…Genetically encoded biosensors based on fluorescent proteins are now widely applicable for monitoring pH changes in live cells. Here, we have shown that a…”
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16
Inhibitory Properties of Nitrogen-Containing Adamantane Derivatives with Monoterpenoid Fragments Against Tyrosyl-DNA Phosphodiesterase I
Published in Bioorganicheskaia khimiia (01-11-2015)“…It was found that compounds combining diazaadamantane and monoterpenoid fragments are potent inhibitors of new structural type of human recombinant DNA repair…”
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17
The Point Mutation in NOGGIN2 Protein That Enhances Its Ability to Bind Activin
Published in Bioorganicheskaia khimiia (01-11-2015)“…Earlier we have revealed the ability of Noggin family proteins to bind a member of the TUF-β superfamily, ActivinB, and to repress the Activin-dependent Smad2…”
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Interaction of DNA Aptamers with the ATP-Dependent Lon Protease from Escherichia coli
Published in Bioorganicheskaia khimiia (01-11-2015)“…ATP-dependent Lon protease of E. coli (Ec-Lon) is a key enzyme of the quality control system of the cell proteome. Ec-Lon subunit comprises N-terminal…”
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Anti-Inflammatory Activity of the Polypeptide of the Sea Anemone, Heteractis crispa
Published in Bioorganicheskaia khimiia (01-11-2015)“…The anti-inflammatory effect of the recombinant polypeptide HCGS 1.20, a Kunitz-type serine protease inhibitor of the sea anemone Heteractis crispa, was…”
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Pioneer Transcription Factors in Normal Development and in Carcinogenesis
Published in Bioorganicheskaia khimiia (01-11-2015)“…Pioneer transcription factors constitute a heterogeneous group of regulatory proteins of animals, which, unlike other transcription factors, are able to…”
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