Search Results - "Biomolecules (Basel, Switzerland)"
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Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
Published in Biomolecules (Basel, Switzerland) (13-11-2019)“…Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate…”
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Immunology of Acute and Chronic Wound Healing
Published in Biomolecules (Basel, Switzerland) (08-05-2021)“…Skin wounds greatly affect the global healthcare system, creating a substantial burden on the economy and society. Moreover, the situation is exacerbated by…”
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Role of Glutathione in Cancer: From Mechanisms to Therapies
Published in Biomolecules (Basel, Switzerland) (09-10-2020)“…Glutathione (GSH) is the most abundant non-protein thiol present at millimolar concentrations in mammalian tissues. As an important intracellular antioxidant,…”
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TGF-β Signaling
Published in Biomolecules (Basel, Switzerland) (23-03-2020)“…Transforming growth factor-β (TGF-β) represents an evolutionarily conserved family of secreted polypeptide factors that regulate many aspects of physiological…”
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Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives
Published in Biomolecules (Basel, Switzerland) (04-04-2022)“…Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and progression of non-enzymatic glycation reaction with proteins and lipids…”
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Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities
Published in Biomolecules (Basel, Switzerland) (30-01-2020)“…Herbal medicinal products have been documented as a significant source for discovering new pharmaceutical molecules that have been used to treat serious…”
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Antidiabetic Potential of Medicinal Plants and Their Active Components
Published in Biomolecules (Basel, Switzerland) (30-09-2019)“…Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood…”
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Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo
Published in Biomolecules (Basel, Switzerland) (19-01-2018)“…Antibiotic resistance is projected as one of the greatest threats to human health in the future and hence alternatives are being explored to combat resistance…”
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Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels
Published in Biomolecules (Basel, Switzerland) (01-09-2019)“…Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming incidence rate and a huge burden on health care providers. DM is…”
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Advanced Hydrogels as Wound Dressings
Published in Biomolecules (Basel, Switzerland) (11-08-2020)“…Skin is the largest organ of the human body, protecting it against the external environment. Despite high self-regeneration potential, severe skin defects will…”
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Phytohormones Regulate Accumulation of Osmolytes Under Abiotic Stress
Published in Biomolecules (Basel, Switzerland) (17-07-2019)“…Plants face a variety of abiotic stresses, which generate reactive oxygen species (ROS), and ultimately obstruct normal growth and development of plants. To…”
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Therapeutic Potential of α- and β-Pinene: A Miracle Gift of Nature
Published in Biomolecules (Basel, Switzerland) (14-11-2019)“…α- and β-pinene are well-known representatives of the monoterpenes group, and are found in many plants' essential oils. A wide range of pharmacological…”
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Paclitaxel's Mechanistic and Clinical Effects on Breast Cancer
Published in Biomolecules (Basel, Switzerland) (27-11-2019)“…Paclitaxel (PTX), the most widely used anticancer drug, is applied for the treatment of various types of malignant diseases. Mechanisms of PTX action represent…”
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Research Progress on the Relationship between Atherosclerosis and Inflammation
Published in Biomolecules (Basel, Switzerland) (23-08-2018)“…Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture, vascular stenosis, or occlusion caused by platelet aggregation and…”
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Neuroprotective Effects of Quercetin in Alzheimer's Disease
Published in Biomolecules (Basel, Switzerland) (30-12-2019)“…Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic potential. It is widely distributed among plants and found commonly in…”
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Role of p53 in the Regulation of Cellular Senescence
Published in Biomolecules (Basel, Switzerland) (08-03-2020)“…The p53 transcription factor plays a critical role in cellular responses to stress. Its activation in response to DNA damage leads to cell growth arrest,…”
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Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology
Published in Biomolecules (Basel, Switzerland) (17-02-2020)“…Reactive oxygen species (ROS) are byproducts of aerobic respiration and signaling molecules that control various cellular functions. Nrf2 governs the gene…”
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Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis
Published in Biomolecules (Basel, Switzerland) (22-06-2021)“…Kaempferol has been shown to protect cells against cerebral ischemia/reperfusion injury through inhibition of apoptosis. In the present study, we sought to…”
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CD44: A Multifunctional Mediator of Cancer Progression
Published in Biomolecules (Basel, Switzerland) (09-12-2021)“…CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated as a cancer stem cell (CSC) marker in several cancers. Cells…”
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Molecular Biomarkers in Cancer
Published in Biomolecules (Basel, Switzerland) (23-07-2022)“…Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer, occurrence of cancer, or patient outcome. They may include germline or…”
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