Search Results - "Biomedicines"

Resveratrol: A Double-Edged Sword in Health Benefits by Salehi, Bahare, Mishra, Abhay Prakash, Nigam, Manisha, Sener, Bilge, Kilic, Mehtap, Sharifi-Rad, Mehdi, Fokou, Patrick Valere Tsouh, Martins, Natália, Sharifi-Rad, Javad

“…Resveratrol (3,5,4'-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group, possessing two phenol rings linked to each other by an ethylene…”
Get full text

Inflammatory Mechanisms Contributing to Endothelial Dysfunction by Theofilis, Panagiotis, Sagris, Marios, Oikonomou, Evangelos, Antonopoulos, Alexios S., Siasos, Gerasimos, Tsioufis, Costas, Tousoulis, Dimitris

“…Maintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including…”
Get full text

Advances in Nanomaterial-Mediated Photothermal Cancer Therapies: Toward Clinical Applications by Han, Hwa Seung, Choi, Ki Young

“…Photothermal therapy (PTT) has attracted extensive research attention as a noninvasive and selective treatment strategy for numerous cancers. PTT functions via…”
Get full text

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics by Bhalani, Dixit V, Nutan, Bhingaradiya, Kumar, Avinash, Singh Chandel, Arvind K

“…The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different…”
Get full text

Modern Wound Dressings: Hydrogel Dressings by Brumberg, Valentin, Astrelina, Tatiana, Malivanova, Tatiana, Samoilov, Alexander

“…Chronic wounds do not progress through the wound healing process in a timely manner and are considered a burden for healthcare system; they are also the most…”
Get full text

The Role of IL-6 in Skin Fibrosis and Cutaneous Wound Healing by Johnson, Blair Z, Stevenson, Andrew W, Prêle, Cecilia M, Fear, Mark W, Wood, Fiona M

“…The timely resolution of wound healing is critical for restoring the skin as a protective barrier. The switch from a proinflammatory to a reparative…”
Get full text

The Role of Angiogenesis in Cancer Treatment by Rajabi, Mehdi, Mousa, Shaker A

“…A number of anti-angiogenesis drugs have been FDA-approved and are being used in cancer treatment, and a number of other agents are in different stages of…”
Get full text

Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway by Tanaka, Masaru, Tóth, Fanni, Polyák, Helga, Szabó, Ágnes, Mándi, Yvette, Vécsei, László

“…The tryptophan (TRP)-kynurenine (KYN) metabolic pathway is a main player of TRP metabolism through which more than 95% of TRP is catabolized. The pathway is…”
Get full text

Zebrafish Larvae as a Behavioral Model in Neuropharmacology by Basnet, Ram Manohar, Zizioli, Daniela, Taweedet, Somrat, Finazzi, Dario, Memo, Maurizio

“…Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark conditions, following the development of a swim bladder at 4 days…”
Get full text

Current FDA-Approved Therapies for High-Grade Malignant Gliomas by Fisher, Jacob P, Adamson, David C

“…The standard of care (SOC) for high-grade gliomas (HGG) is maximally safe surgical resection, followed by concurrent radiation therapy (RT) and temozolomide…”
Get full text

Long-Term Impact of COVID-19: A Systematic Review of the Literature and Meta-Analysis by Sanchez-Ramirez, Diana C., Normand, Kaylene, Zhaoyun, Yang, Torres-Castro, Rodrigo

“…Background: The long-term impact of COVID-19 is still unknown. This study aimed to explore post COVID-19 effects on patients chest computed tomography (CT),…”
Get full text

Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases by Stolfi, Carmine, Maresca, Claudia, Monteleone, Giovanni, Laudisi, Federica

“…The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a critical player in gut homeostasis maintenance as it ensures…”
Get full text

Neuroinflammation in Alzheimer’s Disease by Onyango, Isaac G., Jauregui, Gretsen V., Čarná, Mária, Bennett, James P., Stokin, Gorazd B.

“…Alzheimer’s disease (AD) is a neurodegenerative disease associated with human aging. Ten percent of individuals over 65 years have AD and its prevalence…”
Get full text

Reasons for Failed Trials of Disease-Modifying Treatments for Alzheimer Disease and Their Contribution in Recent Research by Yiannopoulou, Konstantina G, Anastasiou, Aikaterini I, Zachariou, Venetia, Pelidou, Sygkliti-Henrietta

“…Despite all scientific efforts and many protracted and expensive clinical trials, no new drug has been approved by FDA for treatment of Alzheimer disease (AD)…”
Get full text

Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma by Sun, Eun Jin, Wankell, Miriam, Palamuthusingam, Pranavan, McFarlane, Craig, Hebbard, Lionel

“…Despite advances in the treatment of cancers through surgical procedures and new pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains…”
Get full text

Polycrystalline Diamond as a Potential Material for the Hard-on-Hard Bearing of Total Hip Prosthesis: Von Mises Stress Analysis by Ammarullah, Muhammad Imam, Hartono, Rachmad, Supriyono, Toto, Santoso, Gatot, Sugiharto, S, Permana, Muki Satya

“…Due to polymeric wear debris causing osteolysis from polymer, metal ions causing metallosis from metal, and brittle characteristic causing fracture failure…”
Get full text

The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection by Oppedisano, Francesca, Macrì, Roberta, Gliozzi, Micaela, Musolino, Vincenzo, Carresi, Cristina, Maiuolo, Jessica, Bosco, Francesca, Nucera, Saverio, Caterina Zito, Maria, Guarnieri, Lorenza, Scarano, Federica, Nicita, Caterina, Coppoletta, Anna Rita, Ruga, Stefano, Scicchitano, Miriam, Mollace, Rocco, Palma, Ernesto, Mollace, Vincenzo

“…Polyunsaturated fatty acids (n-3 PUFAs) are long-chain polyunsaturated fatty acids with 18, 20 or 22 carbon atoms, which have been found able to counteract…”
Get full text

Modulation of Intracellular Copper Levels as the Mechanism of Action of Anticancer Copper Complexes: Clinical Relevance by Babak, Maria V., Ahn, Dohyun

“…Copper (Cu) is a vital element required for cellular growth and development; however, even slight changes in its homeostasis might lead to severe toxicity and…”
Get full text

Cutaneous Squamous Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches by Fania, Luca, Didona, Dario, Di Pietro, Francesca Romana, Verkhovskaia, Sofia, Morese, Roberto, Paolino, Giovanni, Donati, Michele, Ricci, Francesca, Coco, Valeria, Ricci, Francesco, Candi, Eleonora, Abeni, Damiano, Dellambra, Elena

“…Cutaneous squamous cell carcinoma (cSCC), a non-melanoma skin cancer, is a keratinocyte carcinoma representing one of the most common cancers with an…”
Get full text

Arginine and Endothelial Function by Gambardella, Jessica, Khondkar, Wafiq, Morelli, Marco Bruno, Wang, Xujun, Santulli, Gaetano, Trimarco, Valentina

“…Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle,…”
Get full text