Search Results - "Biomedicine & pharmacotherapy"

Ex vivo transdermal absorption of a liposome formulation of diclofenac by Sacha, Manuel, Faucon, Laetitia, Hamon, Emmanuelle, Ly, Isabelle, Haltner-Ukomadu, Eleonore

“…[Display omitted] •Transdermal drug penetration can be assessed ex-vivo with human skin samples.•3 commercial formulations of diclofenac were tested.•Dermal…”
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Restaging after neoadjuvant chemoradiotherapy for rectal adenocarcinoma: role of F18-FDG PET by CAPIRCI, Carlo, RUBELLO, Domenico, CHIERICHETTI, Franca, CREPALDI, Giorgio, CARPI, Angelo, NICOLINI, Andrea, MANDOLIN, Giovanni, POLICO, Cesare

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Pyroptosis: A new frontier in cancer by Fang, Yuan, Tian, Shengwang, Pan, Yutian, Li, Wei, Wang, Qiming, Tang, Yu, Yu, Tao, Wu, Xi, Shi, Yongkang, Ma, Pei, Shu, Yongqian

“…[Display omitted] •Pyroptosis, is a hot, caspase-1/4/5/11-dependent inflammatory cell death.•Pyroptosis is also an emerging hot spot in cancer.•Pyroptosis…”
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Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management by Rawat, Pushkar Singh, Jaiswal, Aiswarya, Khurana, Amit, Bhatti, Jasvinder Singh, Navik, Umashanker

“…Doxorubicin (Dox) is a secondary metabolite of the mutated strain of Streptomyces peucetius var. Caesius and belongs to the anthracyclines family. The…”
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Photodynamic therapy – mechanisms, photosensitizers and combinations by Kwiatkowski, Stanisław, Knap, Bartosz, Przystupski, Dawid, Saczko, Jolanta, Kędzierska, Ewa, Knap-Czop, Karolina, Kotlińska, Jolanta, Michel, Olga, Kotowski, Krzysztof, Kulbacka, Julita

“…•Photodynamic therapy (PDT) is a contemporary and non-invasive form of anticancer therapy.•PDT dyes characterize by selective accumulation and fluorescent…”
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The emerging role of ferroptosis in inflammation by Sun, Yitian, Chen, Peng, Zhai, Bingtao, Zhang, Mingming, Xiang, Yu, Fang, Jiaheng, Xu, Sinan, Gao, Yufei, Chen, Xin, Sui, Xinbing, Li, Guoxiong

“…•Ferroptosis is triggered by the excessive peroxidation of phospholipid membranes.•Ferroptosis, a kind of regulated necrosis, is immunogenic.•There is a…”
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Adipose tissue and insulin resistance in obese by Ahmed, Bulbul, Sultana, Rifat, Greene, Michael W.

“…[Display omitted] •Long-term overnutrition and obesity develop ectopic fat deposition in different organs causing organelle dysfunctions.•Organelle…”
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Luteolin, a flavonoid, as an anticancer agent: A review by Imran, Muhammad, Rauf, Abdur, Abu-Izneid, Tareq, Nadeem, Muhammad, Shariati, Mohammad Ali, Khan, Imtiaz Ali, Imran, Ali, Orhan, Ilkay Erdogan, Rizwan, Muhammad, Atif, Muhammad, Gondal, Tanweer Aslam, Mubarak, Mohammad S.

“…[Display omitted] Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-cancer compounds. Luteolin (3,4,5,7-tetrahydroxy…”
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Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases by Bai, Jinrong, Zhang, Yunsen, Tang, Ce, Hou, Ya, Ai, Xiaopeng, Chen, Xiaorui, Zhang, Yi, Wang, Xiaobo, Meng, Xianli

“…[Display omitted] Gallic acid (GA), also known as 3,4,5-trihydroxybenzoic acid, is a natural secondary metabolite and widely isolated from various fruits,…”
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Microneedles: A smart approach and increasing potential for transdermal drug delivery system by Waghule, Tejashree, Singhvi, Gautam, Dubey, Sunil Kumar, Pandey, Murali Monohar, Gupta, Gaurav, Singh, Mahaveer, Dua, Kamal

“…The most widely used methods for transdermal administration of the drugs are hypodermic needles, topical creams, and transdermal patches. The effect of most of…”
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Neurobiology and consequences of social isolation stress in animal model—A comprehensive review by Mumtaz, Faiza, Khan, Muhammad Imran, Zubair, Muhammad, Dehpour, Ahmad Reza

“…The brain is a vital organ, susceptible to alterations under genetic influences and environmental experiences. Social isolation (SI) acts as a stressor which…”
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The role of IL-1β and TNF-α in intervertebral disc degeneration by Wang, Yongjie, Che, Mingxue, Xin, Jingguo, Zheng, Zhi, Li, Jiangbi, Zhang, Shaokun

“…•IL-1β and TNF-α are highly expressed in degenerative IVD cells and tissues.•IL-1β and TNF-α play similar and different roles in the pathological process of…”
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The role of m6A RNA methylation in cancer by Sun, Ting, Wu, Ruiyan, Ming, Liang

“…[Display omitted] N6-methyladenosine (m6A), the most abundant internal modification of RNA in eukaryotic cells, has gained increasing attention in recent…”
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Proanthocyanidins: A comprehensive review by Rauf, Abdur, Imran, Muhammad, Abu-Izneid, Tareq, Iahtisham-Ul-Haq, Patel, Seema, Pan, Xiandao, Naz, Saima, Sanches Silva, Ana, Saeed, Farhan, Rasul Suleria, Hafiz Ansar

“…Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because…”
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Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects by Tang, Si-Min, Deng, Xue-Ting, Zhou, Jian, Li, Quan-Peng, Ge, Xian-Xiu, Miao, Lin

“…Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in the daily diet. Previous studies have found that quercetin has many…”
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Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing by Patel, Satish, Srivastava, Shikha, Singh, Manju Rawat, Singh, Deependra

“…[Display omitted] •Diabetes is a multifaceted metabolic disease that effects more than 340 million.•About 20% of them develop diabetic wounds…”
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Cancer immunotherapy: Pros, cons and beyond by Tan, Shuzhen, Li, Dongpei, Zhu, Xiao

“…•Tumor immunotherapy mainly includes ICIs, cellular immunotherapy, exosome immunotherapy, and other novel therapies.•The therapeutic effect of immunotherapy is…”
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Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols by Ansari, Mohammad Yunus, Ahmad, Nashrah, Haqqi, Tariq M

“…[Display omitted] •Here, we discussed the role of oxidative stress and inflammation in OA pathogenesis.•Here, we discussed the antioxidant and…”
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Chlorogenic acid (CGA): A pharmacological review and call for further research by Naveed, Muhammad, Hejazi, Veghar, Abbas, Muhammad, Kamboh, Asghar Ali, Khan, Ghulam Jilany, Shumzaid, Muhammad, Ahmad, Fawwad, Babazadeh, Daryoush, FangFang, Xia, Modarresi-Ghazani, Faezeh, WenHua, Li, XiaoHui, Zhou

“…Phenolic acids have recently gained substantial attention due to their various practical, biological and pharmacological effects. Chlorogenic Acid (CGA, 3-CQA)…”
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EMT, cancer stem cells and autophagy; The three main axes of metastasis by Babaei, Ghader, Aziz, Shiva Gholizadeh-Ghaleh, Jaghi, Nasrin Zare Zavieyh

“…[Display omitted] •EMT, cancer stem cells and autophagy are the three main axes of cancer cell metastasis.•EMT and cancer stem cells are closely related to…”
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