Search Results - "Bioimpacts"

CRISPR-based gene editing in plants: Focus on reagents and their delivery tools by Ebrahimi, Vida, Hashemi, Atieh

“…Introduction: CRISPR-Cas9 technology has revolutionized plant genome editing, providing precise and efficient methods for genetic modification. This study…”
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A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models by Jamshidi, Nazanin, Jamshidi, Negar, Modarresi Chahardehi, Amir, Shams, Elahe, Chaleshi, Vahid

“…Pancreatic ductal adenocarcinoma (PDAC) stands as the fourth leading cause of cancer-related deaths, primarily attributable to its resistance to chemotherapy,…”
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Unveiling the biological effects of radio-frequency and extremelylow frequency electromagnetic fields on the central nervous system performance by Eskandani, Ramin, Zibaii, Mohammad Ismail

“…[...]it is essential to acknowledge that ELF-EMF exposure has also been linked to the induction of anxiety states, oxidative stress, and alterations in…”
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Mesenchymal stromal cells therapy alone does not lead to the complete restoration of the skin parameters in diabetic foot patients within a 3-year follow-up period by Maksimova, Nadezhda V., Michenko, Anna V., Krasilnikova, Olga A., Klabukov, Ilya D., Gadaev, Igor Yu, Krasheninnikov, Michael E., Belkov, Pavel A., Lyundup, Aleksey V.

“…Introduction: Mesenchymal stromal cells (MSCs) administration is an effective option for the treatment of diabetic foot ulcers (DFUs). However, to date,…”
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STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis by Sohrabi, Sepideh, Alipour, Shiva, Ghahramanipour, Zahra, Masoumi, Javad, Baradaran, Behzad

“…Introduction: Signal transducer and activator of transcriptions (STATs) factors as critical proteins in cell signaling regulate diverse biological processes…”
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Cancer treatment comes to age: from one-size-fits-all to nextgeneration sequencing (NGS) technologies by Parvizpour, Sepideh, Beyrampour-Basmenj, Hanieh, Razmara, Jafar, Farhadi, Farhad, Shamsir, Mohd Shahir

“…[...]of this success and the increased accessibility and reliability of sequencing, genomic research has now entered clinical practice. Cancer genomics has…”
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A procedure for DNA methylation assessment in osteoporosis-related gene promoters of umbilical cord blood: A study on the Prospective Epidemiological Research Studies in Iran (PERSIAN) birth cohort by Baradaran Mahdavi, Sadegh, Javadirad, Seyed Morteza, Rafieian, Mahsa, Poursafa, Parnian, Azimian Zavareh, Vajihe, Daniali, Seyede Shahrbanoo, Heidari-Beni, Motahar, Goodarzi-Khoigani, Masoomeh, Vahdatpour, Babak, Mirhendi, Hossein, Kelishadi, Roya

“…Introduction: It is believed that DNA methylation can modify disease susceptibility in response to environmental factors as early as the perinatal period. In…”
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Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues by Ebrahimian Vargahan, Sepideh, Barati, Mahmood, Roudbari, Masoud, Eini, Maryam, Hosseini, Arshad

“…Introduction: Increasing evidence has reported gene expression alterations in breast cancer (BC) tissues, necessitating their investigating to highlight the…”
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The effectiveness of antioxidant agents in delaying progression of diabetic nephropathy: A systematic review of randomized controlled trials by Rahayu, Ika, Arfian, Nur, Kustanti, Christina Yeni, Wahyuningsih, Mae Sri Hartati

“…Introduction: Oxidative stress plays a central role in the pathophysiology of diabetes mellitus and its complications, including diabetic nephropathy…”
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Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells by Tohidast, Maryam, Amini, Mohammad, Doustvandi, Mohammad Amin, Hosseini, Seyed Samad, Bilan, Farzaneh, Mozammel, Nazila, Sameti, Pouryia, Mokhtarzadeh, Amir Ali, Baradaran, Behzad

“…Introduction: Colorectal cancer (CRC) is regarded as a serious global issue and is presently ranked second in the classification of gastrointestinal (GI)…”
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Promising leads against lung cancer from the plants in Lamiaceae family by Rahimlouy Aghdam, Alireza, Hamedeyazdan, Sanaz

“…Introduction: Ceaselessly, management of cancer has been the major global challenge for healthcare professionals. As regards, lung cancer (LC) has been…”
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Intraocular drug delivery systems for Diabetic retinopathy: Current and future prospective by Taheri, Sayed Latif, Poorirani, Safoora, Mostafavi, Sayed Abolfazl

“…In pharmaceutical research and development, novel drug delivery systems represent a significant advancement aimed at enhancing the efficacy of therapeutic…”
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Long-term pulmonary complications in sulfur mustard-exposed patients: gene expression and DNA methylation of OGG1 by Zamani, Mohammad Saber, Ghazanfari, Tooba

“…Introduction: It is well established that tissues exposed to sulfur mustard (SM) generate high levels of reactive oxygen species. This leads to oxidative…”
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Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates by Zarei, Hooman, Movahedin, Mansoureh, Ganji, Fariba, Ghiaseddin, Ali

“…Introduction: The use of releasing scaffolds is promising for testes tissue engineering. Chitosan (CS) is a natural biopolymer extensively used as a delivery…”
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An update on a technical method of cartilage decellularization: (a physical-based protocol) by Dortaj, Hengameh, Vaez, Ahmad, Hassanpour-Dehnavie, Ashraf, Alizadeh, Ali Akbar

“…Introduction: Despite advances in orthopedic surgery, the lack of effective conventional treatment for cartilage defects has led to research in cartilage…”
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SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels by He, Gang, Liu, Mei, Chen, Tang cong, Huang, Li fen, Ke, You qiang

“…Introduction: Fatty acid binding protein 5 (FABP5) exhibits heightened expression levels in triple-negative breast cancer. The inhibitor of FABP5, Stony Brook…”
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Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective by Mortazavi, Seyedeh Maryam, Mohammadi Vadoud, Seyyed Ali, Moghimi, Hamid Reza

“…Introduction: Peptides are promising and attractive anti-wrinkle active ingredients, amongst which glycyl-histidyl-lysine peptide (GHK) is one of the most…”
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Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect by Banimohamad-Shotorbani, Behnaz, Rahbarghazi, Reza, Jarolmasjed, Seyedhosein, Mehdipour, Ahmad, Shafaei, Hajar

“…Introduction: To date, different strategies have been used for co-transplantation of cell-loaded biomaterials for bone tissue regeneration. This study aimed to…”
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Mosaic vaccine design targeting mutational spike protein of SARS- CoV-2: An immunoinformatics approach by Ysrafil, Ysrafil, Imran, Arlan K., Wicita, Prisca Syafriani, Kamba, Vyani, Mohamad, Fihrina, Ismail, Ismail, Nurung, Ayyub Harly, Gama, Noviyanty Indjar, Pratiwi, Sari Eka, Astuti, Indwiani, Nainu, Firzan, Emran, Talha Bin

“…Introduction: Presently, the development of effective vaccines against SARS-CoV-2 is absolutely necessary, especially regarding the emergence of new variants…”
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Oil-in-water nanoemulsions for glaucoma treatment: An insight into the latest trends by Kishore, Ankita, Mahor, Alok Kumar, Singh, Niraj Kumar, Singh, Prem Prakash, Rathore, Priyanka, Bansal, Kuldeep Kumar

“…Glaucoma is a serious eye disease characterized by elevated intraocular pressure, which can ultimately lead to blindness, making it the second leading cause of…”
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