Search Results - "Binz, Sara K"

Replication Protein A Directs Loading of the DNA Damage Checkpoint Clamp to 5′-DNA Junctions by Majka, Jerzy, Binz, Sara K., Wold, Marc S., Burgers, Peter M.J.

“…The heterotrimeric checkpoint clamp comprises the Saccharomyces cerevisiae Rad17, Mec3, and Ddc1 subunits (Rad17/3/1, the 9-1-1 complex in humans). This DNA…”
Get full text

Replication Protein A phosphorylation and the cellular response to DNA damage by Binz, Sara K., Sheehan, Anne M., Wold, Marc S.

“…Defects in cellular DNA metabolism have a direct role in many human disease processes. Impaired responses to DNA damage and basal DNA repair have been…”
Get full text

Regulatory Functions of the N-terminal Domain of the 70-kDa Subunit of Replication Protein A (RPA) by Binz, Sara K., Wold, Marc S.

“…Replication protein A (RPA) is the major single-stranded DNA-binding protein in eukaryotes. RPA is composed of three subunits of 70, 32, and 14 kDa. The…”
Get full text

Functional assays for replication protein A (RPA) by Binz, Sara K, Dickson, Anne M, Haring, Stuart J, Wold, Marc S

“…Replication protein A (RPA) is a heterotrimeric, single-stranded DNA-binding protein. RPA is conserved in all eukaryotes and is essential for DNA replication,…”
Get more information

Catalysis of Strand Annealing by Replication Protein A Derives from Its Strand Melting Properties by Bartos, Jeremy D., Willmott, Lyndsay J., Binz, Sara K., Wold, Marc S., Bambara, Robert A.

“…Eukaryotic DNA-binding protein replication protein A (RPA) has a strand melting property that assists polymerases and helicases in resolving DNA secondary…”
Get full text

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures by Northam, Matthew R, Moore, Elizabeth A, Mertz, Tony M, Binz, Sara K, Stith, Carrie M, Stepchenkova, Elena I, Wendt, Kathern L, Burgers, Peter M J, Shcherbakova, Polina V

“…DNA polymerase ζ (Pol ζ) and Rev1 are key players in translesion DNA synthesis. The error-prone Pol ζ can also participate in replication of undamaged DNA when…”
Get full text

Cellular Functions of Human RPA1: MULTIPLE ROLES OF DOMAINS IN REPLICATION, REPAIR, AND CHECKPOINTS by Haring, Stuart J, Mason, Aaron C, Binz, Sara K, Wold, Marc S

“…In eukaryotes, the single strand DNA (ssDNA)-binding protein, replication protein A (RPA), is essential for DNA replication, repair, and recombination. RPA is…”
Get full text

Lesion bypass by S. cerevisiae Pol ζ alone by Stone, Jana E., Kumar, Dinesh, Binz, Sara K., Inase, Aki, Iwai, Shigenori, Chabes, Andrei, Burgers, Peter M., Kunkel, Thomas A.

“…► Pol ζ participates in translesion synthesis (TLS) of DNA adducts that stall replication fork progression. ► We quantified bypass of abasic sites, cis-syn…”
Get full text

The phosphorylation domain of the 32-kDa subunit of replication protein A (RPA) modulates RPA-DNA interactions. Evidence for an intersubunit interaction by Binz, Sara K, Lao, Ye, Lowry, David F, Wold, Marc S

“…Replication protein A (RPA) is a heterotrimeric (subunits of 70, 32, and 14 kDa) single-stranded DNA-binding protein that is required for DNA replication,…”
Get full text

Replication Protein A Interactions with DNA:  Differential Binding of the Core Domains and Analysis of the DNA Interaction Surface by Wyka, Iwona M, Dhar, Kajari, Binz, Sara K, Wold, Marc S

“…Human replication protein A (RPA) is a heterotrimeric (70, 32, and 14 kDa subunits), eukaryotic single-stranded DNA (ssDNA) binding protein required for DNA…”
Get full text

Cellular Functions of Human RPA1 by Haring, Stuart J., Mason, Aaron C., Binz, Sara K., Wold, Marc S.

“…In eukaryotes, the single strand DNA (ssDNA)-binding protein, replication protein A (RPA), is essential for DNA replication, repair, and recombination. RPA is…”
Get full text

The Phosphorylation Domain of the 32-kDa Subunit of Replication Protein A (RPA) Modulates RPA-DNA Interactions by Binz, Sara K., Lao, Ye, Lowry, David F., Wold, Marc S.

“…Replication protein A (RPA) is a heterotrimeric (subunits of 70, 32, and 14 kDa) single-stranded DNA-binding protein that is required for DNA replication,…”
Get full text

ATP as an Allosteric Modulator and Chelator of Fe 3+ from Fe 3+ ‐transferrin. Is ATP a Major Fe 3+ Carrier by Cowart, Richard E., Shaffer, Tyler B., O'Hara, Ryan D., Campbell, Jacquelyn A., Schneider‐Tugan, Lori L., Binz, Sara K., Pope, Mitchell A., Gregory, Robert B.

“…Abstract only The objectives of this study were to examine two chelators in the removal of Fe 3+ from Fe 3+ ‐transferrin. One was pyrophosphate (PPi) as it is…”
Get full text

ATP as an Allosteric Modulator and Chelator of Fe3+ from Fe3+‐transferrin. Is ATP a Major Fe3+ Carrier by Cowart, Richard E., Shaffer, Tyler B., O'Hara, Ryan D., Campbell, Jacquelyn A., Schneider‐Tugan, Lori L., Binz, Sara K., Pope, Mitchell A., Gregory, Robert B.

“…The objectives of this study were to examine two chelators in the removal of Fe3+ from Fe3+‐transferrin. One was pyrophosphate (PPi) as it is a reasonably…”
Get full text

Replication Protein A Directs Loading of the DNA Damage Checkpoint Clamp to 5′-DNA Junctions by Jerzy Majka, Sara K. Binz, Marc S. Wold, Peter M. J. Burgers

“…The heterotrimeric checkpoint clamp comprises the Saccharomyces cerevisiae Rad17, Mec3, and Ddc1 subunits (Rad17/3/1, the 9-1-1 complex in humans). This DNA…”
Get full text

Replication Protein A phosphorylation and the cellular response to DNA damage: Bridge over broken ends: The cellular response to DNA breaks in health and disease by BINZ, Sara K, SHEEHAN, Anne M, WOLD, Marc S

Get full text