Search Results - "Binienda, Z"

Histopathological and electrophysiological indices of rotenone-evoked dopaminergic toxicity: Neuroprotective effects of acetyl-l-carnitine by Sarkar, S., Gough, B., Raymick, J., Beaudoin, M.A., Ali, S.F., Virmani, A., Binienda, Z.K.

“…•Rotenone evoked dopaminergic neuronal and transporter damage.•Motor conduction velocity and motor latency were affected by rotenone.•A co-treatment with…”
Get full text

Acetyl- l -carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain by Alves, E, Binienda, Z, Carvalho, F, Alves, C.J, Fernandes, E, de Lourdes Bastos, M, Tavares, M.A, Summavielle, T

“…Abstract 3,4-Methylenedioximethamphetamine (MDMA, ecstasy) is a worldwide abused stimulant drug, with persistent neurotoxic effects and high prevalence among…”
Get full text

Propentophylline increases striatal dopamine release but dampens methamphetamine-induced dopamine dynamics: A microdialysis study by Gough, B., Pereira, F.C., Fontes Ribeiro, C.A., Ali, S.F., Binienda, Z.K.

“…While there are currently no medications approved for methamphetamine (METH) addiction, it has been shown that propentofylline (PPF), an atypical…”
Get full text

Acetyl-L-Carnitine Modulates TP53 and IL10 Gene Expression Induced by 3-NPA Evoked Toxicity in PC12 Cells by Virmani, A, Koverech, A, Ali, S F, Binienda, Z K

“…The neurotoxicity induced by the mitochondrial inhibitor 3-nitropropionic acid (3-NPA) is associated with a decrease of ATP synthesis and an increase of free…”
Get full text

Analysis of Electrical Brain Waves in Neurotoxicology: Gamma- Hydroxybutyrate by Binienda, Z K, Beaudoin, M A, Thorn, B T, Ali, S F

“…Advances in computer technology have allowed quantification of the electroencephalogram (EEG) and expansion of quantitative EEG (qEEG) analysis in…”
Get full text

l -Carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture by Wang, C, Sadovova, N, Ali, H.K, Duhart, H.M, Fu, X, Zou, X, Patterson, T.A, Binienda, Z.K, Virmani, A, Paule, M.G, Slikker, W, Ali, S.F

“…Abstract 1-Methyl-4-phenylpyridinium ion (MPP+ ), an inhibitor of mitochondrial complex I, has been widely used as a neurotoxin because it elicits a severe…”
Get full text

Striatal dopamine in the response of brain and liver unsaturated and saturated free fatty acids following administration of C75 in CD-1 mice by Binienda, Z.K., Ross, I.A., Gough, B., Riccio, T., Kim, C.S., Ali, S.F.

“…In order to clarify the mechanism of action of cerulenin analog, C75, known to suppress feeding behavior, food intake was measured in adult CD-1 male mice n =…”
Get full text

Increase in levels of total free fatty acids in rat brain regions following 3-nitropropionic acid administration by Binienda, Zbigniew, Kim, Chung S

“…Acute exposure to a neurotoxin, 3-nitropropionic acid (3-NPA), in rats results in an increase in total free fatty acid (FFA) concentration in selective brain…”
Get full text

Biomarkers of 3-Nitropropionic Acid (3-NPA)-Induced Mitochondrial Dysfunction as Indicators of Neuroprotection by SCALLET, A.C., NONY, P.L., ROUNTREE, R.L., BINIENDA, Z.K.

“…: In humans or animals, symptoms of mitochondrial energy dysfunction may be produced by mutations or inborn errors of the necessary enzymes, as well as by…”
Get full text

Neuroprotective role of l-carnitine in the 3-nitropropionic acid induced neurotoxicity by Binienda, Zbigniew K, Ali, Syed F

“…l-carnitine (LC) plays an important regulatory role in the mitochondrial transport of long-chain free fatty acids (FFA). 3-Nitropropionic acid (3-NPA) is known…”
Get full text

Transplacental Pharmacokinetics and Fetal Distribution of Azidothymidine, Its Glucuronide, and Phosphorylated Metabolites in Late-Term Rhesus Macaques after Maternal Infusion by Tucker A. Patterson, Zbigniew K. Binienda, George W. Lipe, Michael P. Gillam, William Slikker, Jr, Jennifer A. Sandberg

“…3′-Azido-3′-deoxythymidine (AZT) is currently prescribed to pregnant women infected with human immunodeficiency virus to reduce the risk of vertical…”
Get full text

Domoic acid-treated cynomolgus monkeys (M. fascicularis): effects of dose on hippocampal neuronal and terminal degeneration by Scallet, A C, Binienda, Z, Caputo, F A, Hall, S, Paule, M G, Rountree, R L, Schmued, L, Sobotka, T, Slikker, Jr, W

“…Domoic acid is a tricarboxylic amino acid (structurally related to kainic acid and glutamic acid) that is found in the environment as a contaminant of some…”
Get more information

3-Nitropropionic acid (3-NPA) produces hypothermia and inhibits histochemical labeling of succinate dehydrogenase (SDH) in rat brain by NONY, P. A, SCALLET, A. C, ROUNTREE, R. L, YE, X, BINIENDA, Z

“…3-Nitropropionic acid (3-NPA) is a toxin sometimes produced on moldy crops (sugarcane, peanuts, etc.) in amounts sufficient to cause severe neurological…”
Get full text

Introducing Black-Gold II, a highly soluble gold phosphate complex with several unique advantages for the histochemical localization of myelin by Schmued, Larry, Bowyer, John, Cozart, Matthew, Heard, David, Binienda, Zbigniew, Paule, Merle

“…Abstract A novel gold phosphate complex called Black-Gold II with improved myelin staining properties has been developed. It differs from its predecessor,…”
Get full text

Construction of a Physiologically Based Pharmacokinetic Model for 2,4-Dichlorophenoxyacetic Acid Dosimetry in the Developing Rabbit Brain by Kim, C.S., Binienda, Z., Sandberg, J.A.

“…A physiologically based pharmacokinetic (PBPK) model that describes the kinetics of organic anions by using 2,4-dichlorophenoxyacetic acid (2,4-D) as a…”
Get full text

The effect of chronic cocaine exposure during pregnancy on maternal and infant outcomes in the rhesus monkey by Morris, P, Biniendaa, Z, Gillam, M.P, Harkey, M.R, Zhou, C, Henderson, G.L, Paule, M.G

“…To explore the effects of gestational cocaine exposure in a nonhuman primate model, pregnant rhesus monkeys were treated from about 1 month of gestation until…”
Get full text

The effect of chronic cocaine exposure throughout pregnancy on maternal and infant outcomes in the rhesus monkey by Morris, P., Binienda, Z., Gillam, M.P., Klein, J., McMartin, K., Koren, G., Duhart, H.M., Slikker, W., Paule, M.G.

“…To explore the effects of gestational cocaine exposure in a nonhuman primate model, pregnant rhesus monkeys were either treated ( N = 10) with escalating doses…”
Get full text

Effects of Metabolic Modifiers Such as Carnitines, Coenzyme Q10, and PUFAs against Different Forms of Neurotoxic Insults: Metabolic Inhibitors, MPTP, and Methamphetamine by VIRMANI, A.

Get full text

Transplacental pharmacokinetics and maternal/fetal plasma concentrations of cocaine in pregnant macaques near term by Binienda, Z, Bailey, J R, Duhart, H M, Slikker, Jr, W, Paule, M G

“…The transplacental pharmacokinetics of cocaine were studied in three pregnant rhesus monkeys (Macaca mulatta) at 150-154 days of pregnancy (term approximately…”
Get more information

Molecular aspects of dopaminergic neurodegeneration: gene-environment interaction in parkin dysfunction by Ali, Syed F, Binienda, Zbigniew K, Imam, Syed Z

“…Parkinson's disease (PD) is a common neurodegenerative movement disorder that is characterized pathologically by a progressive loss of midbrain dopaminergic…”
Get full text