Search Results - "Bingaman, A. W."

Single‐Center Kidney Paired Donation: The Methodist San Antonio Experience by Bingaman, A. W., Wright Jr, F. H., Kapturczak, M., Shen, L., Vick, S., Murphey, C. L.

“…Many potential kidney transplant recipients are unable to receive a live donor transplant due to crossmatch or blood type incompatibility. Kidney paired…”
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Generation and Functional Capacity of Polyclonal Alloantigen‐Specific Memory CD4 T Cells by Tang, A. L., Bingaman, A. W., Kadavil, E. A., Leeser, D. B., Farber, D. L.

“…Alloreactive memory T cells can significantly impact graft survival due to their enhanced functional capacities, diverse tissue distribution and resistance to…”
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Costimulation Blockade, Busulfan, and Bone Marrow Promote Titratable Macrochimerism, Induce Transplantation Tolerance, and Correct Genetic Hemoglobinopathies with Minimal Myelosuppression by Adams, Andrew B, Durham, Megan M, Kean, Leslie, Shirasugi, Nozomu, Ha, Jongwon, Williams, Matthew A, Rees, Phyllis A, Cheung, Michael C, Mittelstaedt, Stephen, Bingaman, Adam W, Archer, David R, Pearson, Thomas C, Waller, Edmund K, Larsen, Christian P

“…Mixed hemopoietic chimerism has the potential to correct genetic hemological diseases (sickle cell anemia, thalassemia) and eliminate chronic immunosuppressive…”
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Pulsatile pump perfusion of pancreata before human islet cell isolation by Leeser, D.B, Bingaman, A.W, Poliakova, L, Shi, Q, Gage, F, Bartlett, S.T, Farney, A.C

“…Machine pulsatile perfusion for whole pancreas preservation might improve yield, viability, and function of human islets recovered after prolonged cold…”
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Transplantation of the bone marrow microenvironment leads to hematopoietic chimerism without cytoreductive conditioning by BINGAMAN, A. W, WAITZE, S.-Y, ALEXANDER, D. Z, HONG RAE CHO, LIN, A, TUCKER-BURDEN, C, COWAN, S. R, PEARSON, T. C, LARSEN, C. P

“…It has been hypothesized that regimens to induce transplantation tolerance and long-term hematopoietic chimerism require recipient conditioning with whole body…”
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Paired Kidney Donation: A (Virtual) Balancing Act by Bingaman, A. W., Bray, R. A, Gebel, H. M., Newell, K. A.

“…The authors point out that the utility of paired kidney donation programs needs to increasingly be evaluated by real data and real crossmatch results rather…”
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Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection by Trambley, J, Bingaman, A W, Lin, A, Elwood, E T, Waitze, S Y, Ha, J, Durham, M M, Corbascio, M, Cowan, S R, Pearson, T C, Larsen, C P

“…Simultaneous blockade of the CD40 and CD28 costimulatory pathways is an effective treatment strategy to promote allograft acceptance but does not lead to…”
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Cutting Edge: Administration of Anti-CD40 Ligand and Donor Bone Marrow Leads to Hemopoietic Chimerism and Donor-Specific Tolerance Without Cytoreductive Conditioning by Durham, Megan M, Bingaman, Adam W, Adams, Andrew B, Ha, Jongwon, Waitze, Seung-Yeun, Pearson, Thomas C, Larsen, Christian P

“…Transplantation tolerance, defined as allograft acceptance by an immunocompetent recipient in the absence of long-term immunosuppression, has remained an…”
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Vigorous Allograft Rejection in the Absence of Danger by Bingaman, Adam W, Ha, Jongwon, Waitze, Seung-Yeun, Durham, Megan M, Cho, Hong Rae, Tucker-Burden, Carol, Hendrix, Rose, Cowan, Shannon R, Pearson, Thomas C, Larsen, Christian P

“…Tolerance to self is a necessary attribute of the immune system. It is thought that most autoreactive T cells are deleted in the thymus during the process of…”
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Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells by Patke, Deepa S., Ahmadzadeh, Mojgan, Bingaman, Adam W., Farber, Donna L.

“…Anti-CD3 activation of peripheral T cells is used in adoptive immunotherapy for cancer and HIV infection, but the long-term fate of anti-CD3-primed T cells in…”
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Allogeneic Parenchymal and Hematopoietic Tissues Differ in Their Ability to Induce Deletion of Donor‐Reactive T Cells by Jones, Thomas R., Adams, Andrew B., Shirasugi, Nozomu J., Bingaman, Adam W., Durham, Megan M., Pearson and, Thomas C., Larsen, Christian P.

“…The establishment of immune tolerance to self antigen expressed exclusively in the periphery is a crucial yet incompletely understood feature of the immune…”
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A Virtual Crossmatch Protocol Significantly Increases Access of Highly Sensitized Patients to Deceased Donor Kidney Transplantation by BINGATNAN, Adam W, MURPHEY, Cathi L, PALMA-VARGAS, Juan, WRIGHT, Francis

“…Patients with preexisting antihuman leukocyte antigen (HLA) antibodies (sensitized patients) are more likely to have a positive crossmatch with possible donors…”
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Analysis of the CD40 and CD28 pathways on alloimmune responses by CD4+ T cells in vivo by BINGAMAN, Adam W, JONGWON HA, DURHAM, Megan M, WAITZE, Seung-Yeun, TUCKER-BURDEN, Carol, COWAN, Shannon R, PEARSON, Thomas C, LARSEN, Christian P

“…Blockade of the CD40 and CD28 pathways is a powerful strategy to inhibit CD4-mediated alloimmune responses. In this study, we examine the relative roles of the…”
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Fasl is important in costimulation blockade-resistant skin graft rejection by TRAMBLEY, Joel, LIN, Angello, ELWOOD, Eric, BINGAMAN, Adam W, LAKKIS, Fadi, CORBASCIO, Matthias, PEARSON, Thomas C, LARSEN, Christian P

“…Simultaneous blockade of the CD40 and CD28 costimulatory pathways is effective in prolonging allograft survival in murine and primate models. Recent data…”
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The role of CD40L in T cell-dependent nitric oxide production by murine macrophages by Bingaman, Adam W, Pearson, Thomas C, Larsen, Christian P

“…Upon activation, T cells express CD40L, a member of the TNF cytokine superfamily, which serves as a ligand for CD40 on antigen presenting cells, including…”
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Aggressive skin allograft rejection in CD28 −/− mice independent of the CD40/CD40L costimulatory pathway by Ha, Jongwon, Bingaman, Adam W, Durham, Megan M, Pearson, Thomas C, Larsen, Christian P

“…CD28 −/− mice have been utilized to study the role of B7/CD28 and B7-CTLA4 interactions. There is evidence that CTLA4 ligation may be critical for tolerance…”
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A single center experience for kidney paired donation by Murphey, CL, Wright, F, Bingaman, A W

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Memory T Cells in Transplantation: Generation, Function, and Potential Role in Rejection by Bingaman, Adam W., Farber, Donna L.

“…The adaptive immune system is endowed with long‐lived memory to recall previous antigen encounters and respond more effectively to them. Memory immune…”
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Novel phenotypes and migratory properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue by Bingaman, Adam W., Patke, Deepa S., Mane, Vaishali R., Ahmadzadeh, Mojgan, Ndejembi, Modesta, Bartlett, Stephen T., Farber, Donna L.

“…Memory T cells are heterogeneous in expression of lymph node homing receptors, delineating "central‐memory" (TCM, CD62Lhi/CCR7+) and "effector‐memory" (TEM,…”
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ANALYSIS OF T CELL DEPENDENT NITRIC OXIDE PRODUCTION BY MURINE MACROPHAGES by Bingaman, A W, Larsen, C P, Pearson, T C

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