Search Results - "Bindesbøll, Christian"

cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53 by Skah, Seham, Richartz, Nina, Duthil, Eva, Gilljam, Karin M, Bindesbøll, Christian, Naderi, Elin Hallan, Eriksen, Agnete B, Ruud, Ellen, Dirdal, Marta M, Simonsen, Anne, Blomhoff, Heidi Kiil

“…Autophagy is important in regulating the balance between cell death and survival, with the tumor suppressor p53 as one of the key components in this interplay…”
Get full text

MITF has a central role in regulating starvation-induced autophagy in melanoma by Möller, Katrin, Sigurbjornsdottir, Sara, Arnthorsson, Asgeir O., Pogenberg, Vivian, Dilshat, Ramile, Fock, Valerie, Brynjolfsdottir, Solveig H., Bindesboll, Christian, Bessadottir, Margret, Ogmundsdottir, Helga M., Simonsen, Anne, Larue, Lionel, Wilmanns, Matthias, Thorsson, Vesteinn, Steingrimsson, Eirikur, Ogmundsdottir, Margret H.

“…The MITF transcription factor is a master regulator of melanocyte development and a critical factor in melanomagenesis. The related transcription factors TFEB…”
Get full text

NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy by Princely Abudu, Yakubu, Pankiv, Serhiy, Mathai, Benan John, Håkon Lystad, Alf, Bindesbøll, Christian, Brenne, Hanne Britt, Yoke Wui Ng, Matthew, Thiede, Bernd, Yamamoto, Ai, Mutugi Nthiga, Thaddaeus, Lamark, Trond, Esguerra, Camila V., Johansen, Terje, Simonsen, Anne

“…The clearance of damaged or dysfunctional mitochondria by selective autophagy (mitophagy) is important for cellular homeostasis and prevention of disease. Our…”
Get full text

NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease by Bindesbøll, Christian, Aas, Aleksander, Ogmundsdottir, Margret Helga, Pankiv, Serhiy, Reine, Trine, Zoncu, Roberto, Simonsen, Anne

“…Dysregulated cholesterol homeostasis promotes the pathology of atherosclerosis, myocardial infarction and strokes. Cellular cholesterol is mainly regulated at…”
Get full text

Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy by Aas, Aleksander, Isakson, Pauline, Bindesbøll, Christian, Alemu, Endalkachew A, Klungland, Arne, Simonsen, Anne

“…Polymorphic variants of the FTO (fat mass and obesity) gene associate with body mass index in humans, but the underlying molecular mechanisms have not been…”
Get full text

Obesity Increases Disease Activity of Norwegian Patients with Axial Spondyloarthritis: Results from the European Map of Axial Spondyloarthritis Survey by Bindesbøll, Christian, Garrido-Cumbrera, Marco, Bakland, Gunnstein, Dagfinrud, Hanne

“…Objective To investigate the prevalence of overweight and obesity, as well as the association between body mass index (BMI) and disease activity in patients…”
Get full text

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites by Boergesen, Michael, Pedersen, Thomas Åskov, Gross, Barbara, van Heeringen, Simon J., Hagenbeek, Dik, Bindesbøll, Christian, Caron, Sandrine, Lalloyer, Fanny, Steffensen, Knut R., Nebb, Hilde I., Gustafsson, Jan-Åke, Stunnenberg, Hendrik G., Staels, Bart, Mandrup, Susanne

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors by Bindesbøll, Christian, Tan, Susanna, Bott, Debbie, Cho, Tiffany, Tamblyn, Laura, MacPherson, Laura, Grønning-Wang, Line, Nebb, Hilde Irene, Matthews, Jason

“…Members of the poly-ADP-ribose polymerase (PARP) family catalyse the ADP-ribosylation of target proteins and are known to play important roles in many cellular…”
Get more information

Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival by Rahman, Mohummad Aminur, Gras Navarro, Andrea, Brekke, Jorunn, Engelsen, Agnete, Bindesbøll, Christian, Sarowar, Shahin, Bahador, Marzieh, Bifulco, Ersilia, Goplen, Dorota, Waha, Andreas, Lie, Stein Atle, Gjertsen, Bjørn Tore, Selheim, Frode, Enger, Per Øyvind, Simonsen, Anne, Chekenya, Martha

“…Background Resistance to temozolomide (TMZ) is due in part to enhanced DNA repair mediated by high expression of O 6 -methyl guanine DNA methyltransferase (…”
Get full text

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity by Gomez, Alvin, Bindesbøll, Christian, Satheesh, Somisetty V, Grimaldi, Giulia, Hutin, David, MacPherson, Laura, Ahmed, Shaimaa, Tamblyn, Laura, Cho, Tiffany, Nebb, Hilde Irene, Moen, Anders, Anonsen, Jan Haug, Grant, Denis M, Matthews, Jason

“…Here, we report the biochemical characterization of the mono-ADP-ribosyltransferase 2,3,7,8-tetrachlorodibenzo- -dioxin poly-ADP-ribose polymerase…”
Get more information

Through the Eyes of Patients: Understanding Treatment Burden of Intravitreal Anti-VEGF Injections for nAMD Patients in Norway by Reitan, Gudrun, Kjellevold Haugen, Inga Britt, Andersen, Kristoffer, Bragadottir, Ragnheidur, Bindesbøll, Christian

“…Patients with neovascular age-related macular degeneration (nAMD) are treated with frequent intravitreal injections to maintain vision. The treatment frequency…”
Get full text

The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy by Herzog, Laura K., Kevei, Éva, Marchante, Ricardo, Böttcher, Claudia, Bindesbøll, Christian, Lystad, Alf Håkon, Pfeiffer, Annika, Gierisch, Maria E., Salomons, Florian A., Simonsen, Anne, Hoppe, Thorsten, Dantuma, Nico P.

“…The pathology of spinocerebellar ataxia type 3, also known as Machado‐Joseph disease, is triggered by aggregation of toxic ataxin‐3 (ATXN3) variants containing…”
Get full text

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S] by Bindesbøll, Christian, Fan, Qiong, Nørgaard, Rikke C., MacPherson, Laura, Ruan, Hai-Bin, Wu, Jing, Pedersen, Thomas Å., Steffensen, Knut R., Yang, Xiaoyong, Matthews, Jason, Mandrup, Susanne, Nebb, Hilde I., Grønning-Wang, Line M.

“…Liver X receptor (LXR)α and LXRβ play key roles in hepatic de novo lipogenesis through their regulation of lipogenic genes, including sterol regulatory…”
Get full text

Fatty acids regulate perilipin5 in muscle by activating PPARδ[S] by Bindesb⊘ll, Christian, Berg, Ole, Arntsen, Borghild, Nebb, Hilde I., Dalen, Knut Tomas

“…The surface of lipid droplets (LDs) in various cell types is coated with perilipin proteins encoded by the Plin genes. Perilipins regulate LD metabolism by…”
Get full text

Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway by Rahman, Mohummad Aminur, Engelsen, Agnete S T, Sarowar, Shahin, Bindesbøll, Christian, Birkeland, Even, Goplen, Dorota, Lotsberg, Maria L, Knappskog, Stian, Simonsen, Anne, Chekenya, Martha

“…Glioblastoma (GBM) is invariably resistant to temozolomide (TMZ) chemotherapy. Inhibiting the proteasomal pathway is an emerging strategy to accumulate damaged…”
Get full text

BEACH domain proteins function as cargo-sorting adaptors in secretory and endocytic pathways by Pankiv, Serhiy, Dahl, Anette Kathinka, Aas, Aleksander, Andersen, Rosa Linn, Brech, Andreas, Holland, Petter, Singh, Sakshi, Bindesbøll, Christian, Simonsen, Anne

“…We identify BEACH domain–containing proteins (BDCPs) as novel membrane coat proteins involved in the sorting of transmembrane proteins (TMPs) on the…”
Get full text

LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice by Fan, Qiong, Nørgaard, Rikke C, Bindesbøll, Christian, Lucas, Christin, Dalen, Knut Tomas, Babaie, Eshrat, Itkonen, Harri M, Matthews, Jason, Nebb, Hilde I, Grønning-Wang, Line M

“…Liver X receptors (LXRα/β) and carbohydrate response element-binding proteins (ChREBPα/β) are key players in the transcriptional control of hepatic…”
Get full text

Regulation of angiopoietin‐like protein 4 production during and after exercise by Norheim, Frode, Hjorth, Marit, Langleite, Torgrim M., Lee, Sindre, Holen, Torgeir, Bindesbøll, Christian, Stadheim, Hans K., Gulseth, Hanne L., Birkeland, Kåre I., Kielland, Anders, Jensen, Jørgen, Dalen, Knut T., Drevon, Christian A.

“…Angiopoietin‐like protein 4 (ANGPTL4) may regulate lipoprotein lipase‐dependent plasma clearance of triacylglycerol from skeletal muscle during exercise. The…”
Get full text

LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction by Fan, Qiong, Nørgaard, Rikke Christine, Grytten, Ivar, Ness, Cecilie Maria, Lucas, Christin, Vekterud, Kristin, Soedling, Helen, Matthews, Jason, Lemma, Roza Berhanu, Gabrielsen, Odd Stokke, Bindesbøll, Christian, Ulven, Stine Marie, Nebb, Hilde Irene, Grønning-Wang, Line Mariann, Sæther, Thomas

“…The cholesterol-sensing nuclear receptor liver X receptor (LXR) and the glucose-sensing transcription factor carbohydrate responsive element-binding protein…”
Get full text

Perilipin 4 in human skeletal muscle: localization and effect of physical activity by Pourteymour, Shirin, Lee, Sindre, Langleite, Torgrim M., Eckardt, Kristin, Hjorth, Marit, Bindesbøll, Christian, Dalen, Knut T., Birkeland, Kåre I., Drevon, Christian A., Holen, Torgeir, Norheim, Frode

“…Perilipins (PLINs) coat the surface of lipid droplets and are important for the regulation of lipid turnover. Knowledge about the physiological role of the…”
Get full text